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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 3 of 3 Research Studies DisplayedFan T, Uptegraft C
AHRQ Author: Fan T
Screening for ovarian cancer.
This case study addresses the U.S. Preventive Health Service Task Force recommendations and offers a scenario, questions, and answers related to screening for ovarian cancer.
AHRQ-authored.
Citation: Fan T, Uptegraft C .
Screening for ovarian cancer.
Am Fam Physician 2018 Jun 15;97(12):813-14..
Keywords: Cancer: Ovarian Cancer, Case Study, Prevention, Screening, U.S. Preventive Services Task Force (USPSTF)
Henderson JT, Webber EM, Sawaya GF
Screening for ovarian cancer: Updated evidence report and systematic review for the US Preventive Services Task Force.
The researchers systematically reviewed evidence on benefits and harms of ovarian cancer screening among average-risk women to inform the United States Preventive Services Task Force. They concluded that, in randomized trials conducted among average-risk, asymptomatic women, ovarian cancer mortality did not significantly differ between screened women and those with no screening or in usual care.
AHRQ-funded; 290201500007I.
Citation: Henderson JT, Webber EM, Sawaya GF .
Screening for ovarian cancer: Updated evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2018 Feb 13;319(6):595-606. doi: 10.1001/jama.2017.21421.
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Keywords: Evidence-Based Practice, Guidelines, Cancer: Ovarian Cancer, Screening, U.S. Preventive Services Task Force (USPSTF)
Nelson HD, Pappas M, Zakher B
Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women: a systematic review to update the U.S. Preventive Services Task Force recommendation.
This systematic review was done in support of the U.S. Preventive Services Task Force (USPSTF) updated recommendation on the benefit and harms of risk assessment, genetic testing, and genetic counseling for BRCA-related cancer in women. A systematic review was done on literature from 2004 to July 30, 2013 from MEDLINE, PsycINFO, the Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Health Technology Assessment, Scopus, and reference lists. Data on the participants, study design, analysis, follow-up, and results was extracted and a second investigator confirmed key data. The studies were rated on study quality and applicability. The analysis found women with high-risk for breast cancer had decreased risk of breast cancer by 85% to 100% by having a mastectomy, and risk of mortality by 81% to 100% compared to women without surgery. There was also a lower risk of breast and ovarian cancer after having salpingo-oopherectomy surgery.
AHRQ-funded; 290200710057
Citation: Nelson HD, Pappas M, Zakher B .
Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women: a systematic review to update the U.S. Preventive Services Task Force recommendation.
Ann Intern Med 2014 Feb 18;160(4):255-66. doi: 10.7326/m13-1684..
Keywords: U.S. Preventive Services Task Force (USPSTF), Cancer: Breast Cancer, Cancer: Ovarian Cancer, Cancer, Genetics, Screening, Prevention, Guidelines, Evidence-Based Practice, Women, Risk, Family Health and History