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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 1 of 1 Research Studies DisplayedPepper DJ, Demirkale CY, Sun J
Does obesity protect against death in sepsis? A retrospective cohort study of 55,038 adult patients.
The purpose of this study was to estimate the relationship between body mass index and sepsis mortality using detailed clinical data for case detection and risk adjustment. In adults with clinically-defined sepsis, results demonstrated lower short-term mortality in patients with higher body mass indices compared with those with normal body mass indices and higher short-term mortality in those with low body mass indices. Understanding how obesity improves survival in sepsis would inform prognostic and therapeutic strategies.
AHRQ-funded; HS025008.
Citation: Pepper DJ, Demirkale CY, Sun J .
Does obesity protect against death in sepsis? A retrospective cohort study of 55,038 adult patients.
Crit Care Med 2019 May;47(5):643-50. doi: 10.1097/ccm.0000000000003692..
Keywords: Sepsis, Obesity, Mortality