National Healthcare Quality and Disparities Report
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 2 of 2 Research Studies DisplayedYin MT, Shiau S, Rimland D
Fracture prediction with modified-FRAX in older HIV-infected and uninfected men.
The authors investigated considering HIV as a cause of secondary osteoporosis when calculating FRAX, a clinical fracture risk calculator, in HIV-infected individuals. They found that modified-FRAX underestimated the fracture rates more in older HIV-infected than in otherwise similar uninfected men. and they recommend further studies to determine how to risk stratify for screening and treatment in older HIV-infected individuals.
AHRQ-funded; HS018372.
Citation: Yin MT, Shiau S, Rimland D .
Fracture prediction with modified-FRAX in older HIV-infected and uninfected men.
J Acquir Immune Defic Syndr 2016 Aug 15;72(5):513-20. doi: 10.1097/qai.0000000000000998.
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Keywords: Clinical Decision Support (CDS), Elderly, Injuries and Wounds, Human Immunodeficiency Virus (HIV), Risk
Crane HM, Heckbert SR, Drozd DR
Lessons learned from the design and implementation of myocardial infarction adjudication tailored for HIV clinical cohorts.
In this study, a team of researchers developed, implemented, and evaluated a myocardial infarction (MI) adjudication protocol for cohort research of human immunodeficiency virus. They found that central adjudication is crucial and that clinical diagnoses alone are insufficient for ascertainment of MI. Over half the events ultimately determined to be MIs were not identified by clinical diagnoses.
AHRQ-funded; HS019515
Citation: Crane HM, Heckbert SR, Drozd DR .
Lessons learned from the design and implementation of myocardial infarction adjudication tailored for HIV clinical cohorts.
Am J Epidemiol. 2014 Apr 15;179(8):996-1005. doi: 10.1093/aje/kwu010..
Keywords: Human Immunodeficiency Virus (HIV), Heart Disease and Health, Clinical Decision Support (CDS), Diagnostic Safety and Quality