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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 18 of 18 Research Studies DisplayedShah SC, Tarassishin L, Eisele C
Breastfeeding is associated with lower likelihood of Helicobacter pylori colonization in babies, based on a prospective USA maternal-infant cohort.
The authors evaluated maternal and baby factors associated with likelihood of H. pylori colonization in the babies. They found that H. pylori prevalence was 31.8% in mothers and 19.7% in their babies. Dominant breastfeeding and maternal IBD were associated with significantly lower likelihood of H. pylori colonization among babies; no other clinical factors were associated with H. pylori colonization in the babies. They concluded that dominant breastfeeding may protect against early H. pylori colonization.
AHRQ-funded; HS026395.
Citation: Shah SC, Tarassishin L, Eisele C .
Breastfeeding is associated with lower likelihood of Helicobacter pylori colonization in babies, based on a prospective USA maternal-infant cohort.
Dig Dis Sci 2022 Nov;67(11):5149-57. doi: 10.1007/s10620-021-07371-x..
Keywords: Newborns/Infants, Breast Feeding, Evidence-Based Practice
Safon CB, Heeren TC, Kerr SM
Disparities in breastfeeding among U.S. Black mothers: identification of mechanisms.
Disparities in U.S. breastfeeding rates persist among Black mothers according to birth country and between Black and White mothers, necessitating further investigation of modifiable mediating factors to inform interventions. This study sought to examine the extent that social, maternal, infant factors and Theory of Planned Behavior (TPB) domains (attitudes, perceived control, and subjective norms) mediated the association of maternal race/birth country and breastfeeding continuation.
AHRQ-funded; HS022242.
Citation: Safon CB, Heeren TC, Kerr SM .
Disparities in breastfeeding among U.S. Black mothers: identification of mechanisms.
Breastfeed Med 2021 Feb;16(2):140-49. doi: 10.1089/bfm.2020.0310..
Keywords: Breast Feeding, Racial and Ethnic Minorities, Disparities, Maternal Care, Women
Simpson KR, Lyndon A, Spetz J
Missed nursing care during labor and birth and exclusive breast milk feeding during hospitalization for childbirth.
The purpose of this study was to determine associations between missed nursing care and nurse staffing during labor and birth, and exclusive breast milk feeding at hospital discharge. Exclusive breast milk feeding is a national quality indicator of inpatient maternity care. Nurses have substantial responsibility for direct support of infant feeding during the childbirth hospitalization. The investigators indicate that the results support exclusive breast milk feeding as a nurse-sensitive quality indicator.
AHRQ-funded; HS025715.
Citation: Simpson KR, Lyndon A, Spetz J .
Missed nursing care during labor and birth and exclusive breast milk feeding during hospitalization for childbirth.
MCN Am J Matern Child Nurs 2020 Sep/Oct;45(5):280-88. doi: 10.1097/nmc.0000000000000644..
Keywords: Labor and Delivery, Pregnancy, Maternal Care, Breast Feeding, Inpatient Care, Nursing, Women
Jefferson UT, Zachary I, Majee W
Employing a user-centered design to engage mothers in the development of a mHealth breastfeeding application.
The Mother's Milk Connection mHealth application was designed to improve breastfeeding duration and access to support. This article describes a user-centered design process to engage mothers in the development of the Mother's Milk Connection application. Stakeholder and user engagement indicated the integration of four distinct features acceptable for use as a comprehensive mHealth intervention to improve access to breastfeeding support. Further, mHealth has the potential to be a useful strategy for providing breastfeeding support, and a clinical trial regarding the efficacy of the Mother's Milk Connection application is needed.
AHRQ-funded; HS022140.
Citation: Jefferson UT, Zachary I, Majee W .
Employing a user-centered design to engage mothers in the development of a mHealth breastfeeding application.
Comput Inform Nurs 2019 Oct;37(10):522-31. doi: 10.1097/cin.0000000000000549..
Keywords: Breast Feeding, Maternal Care, Pregnancy, Women, Health Information Technology (HIT), Patient and Family Engagement, Patient Adherence/Compliance, Health Promotion, Education: Patient and Caregiver, Caregiving
Ray KN, Demirci JR, Uscher-Pines L
Geographic access to international board-certified lactation consultants in Pennsylvania.
The goals of this study were to assess geographic access to international board-certified lactation consultants in Pennsylvania, to compare access in rural vs. urban counties, and to compare access by county-level breastfeeding initiation rates. Researchers used geographic information systems methodology and a cross-sectional observational design to calculate the proportion of all young children, children in urban and rural counties, children in counties with low, medium, and high breastfeeding initiation rates who lived within specific distances of board-certified lactation consultants in Pennsylvania. Comparisons were made to answer the research goals. While the results indicate that most Pennsylvania children live in proximity to a board-certified lactation consultant, a lower percentage of children in rural counties and in counties with lower breastfeeding rates do.
AHRQ-funded; HS022989.
Citation: Ray KN, Demirci JR, Uscher-Pines L .
Geographic access to international board-certified lactation consultants in Pennsylvania.
J Hum Lact 2019 Feb;35(1):90-99. doi: 10.1177/0890334418768458..
Keywords: Access to Care, Breast Feeding, Newborns/Infants, Rural Health
Aguirre TM, Koehler AE, Joshi A
Recruitment and retention challenges and successes.
This study presents strategies used to successfully recruit and retain rural Hispanic women during a breastfeeding education intervention. The authors found that phone assessments facilitated participation as transportation was an issue. In addition, accommodating requests to deliver or mail study materials and providing incentives were important. Extra effort was needed to maintain contact when phone service was disrupted or participants moved. Keys to success were persistence, flexibility, and alleviating barriers to participation.
AHRQ-funded; HS021321.
Citation: Aguirre TM, Koehler AE, Joshi A .
Recruitment and retention challenges and successes.
Ethn Health 2018 Jan;23(1):111-19. doi: 10.1080/13557858.2016.1246427..
Keywords: Breast Feeding, Racial and Ethnic Minorities, Education: Patient and Caregiver, Women
Lipira L, Kemp C, Domercant JW
The role of service readiness and health care facility factors in attrition from Option B+ in Haiti: a joint examination of electronic medical records and service provision assessment survey data.
Option B+ is a strategy wherein pregnant or breastfeeding women with HIV are enrolled in lifelong antiretroviral therapy (ART) for prevention of mother-to-child transmission (PMTCT) of HIV. This study explored service readiness and other facility factors as predictors of Option B+ attrition in Haiti. The study found that several facility-level factors were associated with Option B+ attrition.
AHRQ-funded; HS013853.
Citation: Lipira L, Kemp C, Domercant JW .
The role of service readiness and health care facility factors in attrition from Option B+ in Haiti: a joint examination of electronic medical records and service provision assessment survey data.
Int Health 2018 Jan;10(1):54-62. doi: 10.1093/inthealth/ihx060..
Keywords: Breast Feeding, Electronic Health Records (EHRs), Human Immunodeficiency Virus (HIV), Prevention, Women
Abrams EM, Greenhawt M, Fleischer DM
Early solid food introduction: role in food allergy prevention and implications for breastfeeding.
The authors explore the evidence suggesting that introduction of solid foods before age 6 months might reduce the risk of food allergy. In addition, they review the possible implications of earlier solid food introduction on both the benefits of exclusive breastfeeding and the total duration of breastfeeding. Finally, they argue that harmonization of early introduction guidelines with breastfeeding guidelines is needed to maximize the benefits of both exclusive breastfeeding and early complementary food introduction
AHRQ-funded; HS024599.
Citation: Abrams EM, Greenhawt M, Fleischer DM .
Early solid food introduction: role in food allergy prevention and implications for breastfeeding.
J Pediatr 2017 May;184:13-18. doi: 10.1016/j.jpeds.2017.01.053.
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Keywords: Breast Feeding, Newborns/Infants, Newborns/Infants, Nutrition, Prevention
Kato E, Rajupet S
Primary interventions to support breastfeeding.
This case study involves a 26-year-old woman, who presents for a routine prenatal visit at 28 weeks’ gestation. Her medical history is significant for poorly controlled asthma, and her family history is significant for breast cancer diagnosed in her mother. It poses three multiple choice questions together with the U.S. Preventive Services Task Force recommendations and related background information.
AHRQ-authored.
Citation: Kato E, Rajupet S .
Primary interventions to support breastfeeding.
Am Fam Physician 2017 Apr 15;95(8):517-18.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Breast Feeding, Primary Care, Pregnancy, Asthma
Greenhawt M, Venter C
Having your cake and EATing it too: early timing of multiple allergen introduction does not increase the risk of developing food allergy in standard risk, breastfed infants.
This study sought to determine if there is a protective association between early allergen introduction and a reduced risk of developing food allergy in high-risk infants, but not in standard-risk children. Overall, it found no difference in the rate of food allergy development with introduction of potentially allergenic solids at 3 vs 6 months.
AHRQ-funded; HS024599.
Citation: Greenhawt M, Venter C .
Having your cake and EATing it too: early timing of multiple allergen introduction does not increase the risk of developing food allergy in standard risk, breastfed infants.
Evid Based Med 2017 Apr;22(2):60. doi: 10.1136/ebmed-2016-110488.
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Keywords: Breast Feeding, Newborns/Infants, Newborns/Infants
Patnode CD, Henninger ML, Senger CA
Primary care interventions to support breastfeeding: updated evidence report and systematic review for the US Preventive Services Task Force.
This updated report found no significant association between interventions and breastfeeding initiation . There was limited mixed evidence of an association between system-level interventions and rates of breastfeeding from well-controlled studies as well as for harms related to breastfeeding interventions, including maternal anxiety scores, decreased confidence, and concerns about confidentiality.
AHRQ-funded.
Citation: Patnode CD, Henninger ML, Senger CA .
Primary care interventions to support breastfeeding: updated evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2016 Oct 25;316(16):1694-705. doi: 10.1001/jama.2016.8882.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Breast Feeding, Primary Care, Evidence-Based Practice, Guidelines
Burca ND, Gephart SM
Promoting breast milk nutrition in infants with cleft lip and/or palate.
The purpose of this article was to present (1) scientific evidence that supports clinical feeding practices for the infant with cleft lip/palate (CL/P) and (2) teaching strategies for staff and parents. Special considerations for feeding infants with CL/P include assessing the infant's sucking ability, demonstrating proper breastfeeding positioning, supporting mothers to establish and maintain their milk supply, considering adaptive feeding equipment (ie, specialized bottles and nipples), and education about the benefits of human milk.
AHRQ-funded; HS022908.
Citation: Burca ND, Gephart SM .
Promoting breast milk nutrition in infants with cleft lip and/or palate.
Adv Neonatal Care 2016 Oct;16(5):337-44. doi: 10.1097/anc.0000000000000305..
Keywords: Breast Feeding, Education: Patient and Caregiver
Joshi A, Amadi C, Meza J
Comparison of socio-demographic characteristics of a computer based breastfeeding educational intervention among rural Hispanic women.
The purpose of this study was to examine association between socio-demographic characteristics and breastfeeding knowledge, self-efficacy and breastfeeding attrition prediction among rural Hispanic women. It found a significant positive association between self-efficacy and intent to breastfeed. Self-efficacy is an important predictor of intent to breastfeed among rural Hispanic women.
AHRQ-funded; HS021321.
Citation: Joshi A, Amadi C, Meza J .
Comparison of socio-demographic characteristics of a computer based breastfeeding educational intervention among rural Hispanic women.
J Community Health 2015 Oct;40(5):993-1001. doi: 10.1007/s10900-015-0023-3..
Keywords: Breast Feeding, Health Information Technology (HIT), Rural Health, Education: Patient and Caregiver, Racial and Ethnic Minorities
Masho SW, Cha S, Morris MR
Prepregnancy obesity and breastfeeding noninitiation in the United States: an examination of racial and ethnic differences.
This study used a large, nationally representative sample to assess racial/ethnic differences in breastfeeding noninitiation among U.S. women of different body mass index (BMI) classifications. It found that prepregnancy BMI is a significant predictor for breastfeeding noninitiation for non-Hispanic white and non-Hispanic black women.
AHRQ-funded; HS021504.
Citation: Masho SW, Cha S, Morris MR .
Prepregnancy obesity and breastfeeding noninitiation in the United States: an examination of racial and ethnic differences.
Breastfeed Med 2015 Jun;10(5):253-62. doi: 10.1089/bfm.2015.0006..
Keywords: Breast Feeding, Obesity, Racial and Ethnic Minorities, Racial and Ethnic Minorities
Francis DO, Krishnaswami S, Mcpheeters M
Treatment of ankyloglossia and breastfeeding outcomes: a systematic review.
This systematic review of literature on surgical and nonsurgical treatments for infants with ankyloglossia, a condition restricting tongue mobility in infants, found that frenotomy may be associated with mother-reported improvements in breastfeeding, and potentially in nipple pain. Since the existing studies are small and short-term with inconsistent methodology, the strength of the evidence is low to insufficient.
AHRQ-funded; 290201200009I.
Citation: Francis DO, Krishnaswami S, Mcpheeters M .
Treatment of ankyloglossia and breastfeeding outcomes: a systematic review.
Pediatrics 2015 Jun;135(6):e1458-66. doi: 10.1542/peds.2015-0658..
Keywords: Breast Feeding, Outcomes, Comparative Effectiveness, Evidence-Based Practice, Newborns/Infants
Chinnadurai S, Francis DO, Epstein RA
Treatment of ankyloglossia for reasons other than breastfeeding: a systematic review.
The researchers systematically reviewed literature on feeding, speech, and social outcomes of treatments for infants and children with ankyloglossia. After analyzing two randomized controlled trials, 2 cohort studies, and 11 case series assessing the effects of frenotomy on feeding, speech, and social outcomes, they determined that data are currently insufficient for assessing the effects of frenotomy on nonbreastfeeding outcomes that may be associated with ankyloglossia.
AHRQ-funded; 290201200009I.
Citation: Chinnadurai S, Francis DO, Epstein RA .
Treatment of ankyloglossia for reasons other than breastfeeding: a systematic review.
Pediatrics 2015 Jun;135(6):e1467-74. doi: 10.1542/peds.2015-0660..
Keywords: Breast Feeding, Children/Adolescents, Outcomes, Comparative Effectiveness
Joshi A, Perin DM, Amadi C
Evaluating the usability of an interactive, bi-lingual, touchscreen-enabled breastfeeding educational programme: application of Nielson's heuristics.
The study purpose was to conduct heuristic evaluation of an interactive, bilingual touchscreen-enabled breastfeeding educational program for Hispanic women living in rural settings in Nebraska. The results demonstrated that the system was more consistent with Nielsen’s usability heuristics. With Nielsen’s usability heuristics, it is possible to identify problems in a timely manner.
AHRQ-funded; HS021321.
Citation: Joshi A, Perin DM, Amadi C .
Evaluating the usability of an interactive, bi-lingual, touchscreen-enabled breastfeeding educational programme: application of Nielson's heuristics.
J Innov Health Inform 2015 Mar 5;22(2):265-74. doi: 10.14236/jhi.v22i2.71..
Keywords: Health Information Technology (HIT), Education: Patient and Caregiver, Rural Health, Breast Feeding, Racial and Ethnic Minorities
Kadakia A, Joyner B, Tender J
Breastfeeding in African Americans may not depend on sleep arrangement: a mixed-methods study.
The researchers described the association between breastfeeding and bedsharing, elucidating barriers to breastfeeding in African Americans. They found that lower socioeconomic status mothers were more likely to breastfeed exclusively or at all if they bedshared; however, bedsharing was not associated with breastfeeding among higher socioeconomic status mothers. Breast pain, lack of support, and maternal skepticism about breastfeeding benefits were barriers.
AHRQ-funded; HS016892.
Citation: Kadakia A, Joyner B, Tender J .
Breastfeeding in African Americans may not depend on sleep arrangement: a mixed-methods study.
Clin Pediatr 2015 Jan;54(1):47-53. doi: 10.1177/0009922814547565.
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Keywords: Breast Feeding, Racial and Ethnic Minorities, Sleep Problems, Social Determinants of Health, Women, Maternal Care
