National Healthcare Quality and Disparities Report
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- Adverse Events (1)
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- (-) Respiratory Conditions (18)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 18 of 18 Research Studies DisplayedWickwire EM, Bailey MD, Somers VK
CPAP adherence is associated with reduced inpatient utilization among older adult Medicare beneficiaries with pre-existing cardiovascular disease.
The purpose of this study was to examine the impact of adherence to continuous positive airway pressure (CPAP) therapy on health care utilization among a nationally representative and sample of older adults with multiple morbidities and pre-existing cardiovascular disease and subsequently diagnosed with obstructive sleep apnea in the United States. The investigators concluded that in this nationally representative sample of older Medicare beneficiaries with multiple morbidities and relative to low adherers, high adherers demonstrated reduced inpatient utilization.
AHRQ-funded; HS024560.
Citation: Wickwire EM, Bailey MD, Somers VK .
CPAP adherence is associated with reduced inpatient utilization among older adult Medicare beneficiaries with pre-existing cardiovascular disease.
J Clin Sleep Med 2022 Jan;18(1):39-45. doi: 10.5664/jcsm.9478..
Keywords: Elderly, Medicare, Sleep Problems, Cardiovascular Conditions, Patient Adherence/Compliance, Hospitalization, Healthcare Utilization, Respiratory Conditions
Tandan M, Zimmerman S, Sloane PD
Which nursing home residents with pneumonia are managed on-site and which are hospitalized? Results from 2 years' surveillance in 14 US homes.
Pneumonia is a frequent cause of hospitalization among nursing home (NH) residents, but little information is available as to how clinical presentation and other characteristics relate to hospitalization, and the differential use of antimicrobials based on hospitalization status. This study examined how hospitalized and nonhospitalized NH residents with pneumonia differ. The investigators concluded that respiratory rate was associated with hospitalization but was not documented for more than a quarter of residents.
AHRQ-funded; HS022298.
Citation: Tandan M, Zimmerman S, Sloane PD .
Which nursing home residents with pneumonia are managed on-site and which are hospitalized? Results from 2 years' surveillance in 14 US homes.
J Am Med Dir Assoc 2020 Dec;21(12):1862-68.e3. doi: 10.1016/j.jamda.2020.07.028..
Keywords: Elderly, Nursing Homes, Pneumonia, Respiratory Conditions, Hospitalization
Iyer AS, Goodrich CA, Dransfield MT
End-of-life spending and healthcare utilization among older adults with chronic obstructive pulmonary disease.
This study examined end-of-life spending and healthcare utilization among Medicare beneficiaries aged 65 years or older with chronic obstructive pulmonary disease (COPD) who died during the period 2013-2014. Data on 146,240 decedents with COPD was investigated from 306 hospital referral regions (HRRs). The overall spending during the last 2 years of life varied significantly nationwide. Inpatient care accounted for 40.2% of spending, with 82% of decedents admitted to the hospital for 13.7±3.1 days and 55%±11% admitted to an intensive care unit for 3-7 days. Skilled nursing facilities accounted for 11.6% of spending and were utilized by 31-45% of decedents for 14-23 days. Hospitals were utilized by 39-56% of decedents and accounted for 10.3% of spending.
AHRQ-funded; HS023009.
Citation: Iyer AS, Goodrich CA, Dransfield MT .
End-of-life spending and healthcare utilization among older adults with chronic obstructive pulmonary disease.
Am J Med 2020 Jul;133(7):817-24.e1. doi: 10.1016/j.amjmed.2019.11.024..
Keywords: Elderly, Healthcare Utilization, Respiratory Conditions, Chronic Conditions, Healthcare Costs, Palliative Care
Singh M, Duarte AG, Hsu ES
Trends and factors associated with nebulized therapy prescription in older adults with chronic obstructive pulmonary disease from 2008 to 2015.
Medical management of patients with chronic obstructive pulmonary disease (COPD) includes nebulized therapy as an option for inhalational drug delivery. A broad variety of short- and long-acting bronchodilators and inhaled corticosteroids in the nebulized form are available. Despite this, limited information exists on the pattern and predictors of nebulized prescription. In this retrospective cross-sectional study, the investigators examined the trend and factors associated with prescription of nebulized therapy among Medicare beneficiaries with COPD.
AHRQ-funded; HS020642.
Citation: Singh M, Duarte AG, Hsu ES .
Trends and factors associated with nebulized therapy prescription in older adults with chronic obstructive pulmonary disease from 2008 to 2015.
J Aerosol Med Pulm Drug Deliv 2020 Jun;33(3):161-69. doi: 10.1089/jamp.2019.1582..
Keywords: Elderly, Respiratory Conditions, Chronic Conditions, Medication
Makam AN, Nguyen OK, Xuan L
Long-term acute care hospital use of non-mechanically ventilated hospitalized older adults.
In this observational cohort study, the investigators sought to determine why non-mechanically ventilated hospitalized older adults are transferred to long-term acute care (LTAC) hospitals rather than remaining in the hospital. The authors found that nearly half of the variation in LTAC use is independent of illness severity and is explained by which hospital and what region the individual was hospitalized in.
AHRQ-funded; HS022418.
Citation: Makam AN, Nguyen OK, Xuan L .
Long-term acute care hospital use of non-mechanically ventilated hospitalized older adults.
J Am Geriatr Soc 2018 Nov;66(11):2112-19. doi: 10.1111/jgs.15564..
Keywords: Elderly, Hospitalization, Long-Term Care, Respiratory Conditions
Chaaban MR, Zhang D, Resto V
Factors influencing recurrent emergency department visits for epistaxis in the elderly.
The objective of the study was to determine the risk factors associated with recurrent epistaxis requiring emergency department (ED) visits in the elderly. The investigators concluded that additional ED visits for epistaxis were more common in the elderly and in males. Congestive heart failure, diabetes mellitus and obstructive sleep apnea were found to be independent risk factors.
AHRQ-funded; HS022134.
Citation: Chaaban MR, Zhang D, Resto V .
Factors influencing recurrent emergency department visits for epistaxis in the elderly.
Auris Nasus Larynx 2018 Aug;45(4):760-64. doi: 10.1016/j.anl.2017.11.010..
Keywords: Elderly, Emergency Department, Risk, Respiratory Conditions, Healthcare Utilization
Iyer AS, Benzo RP, Bakitas MA
Easing the tension between palliative care and intensive care in chronic obstructive pulmonary disease.
This editorial discusses palliative care and intensive care in chronic obstructive pulmonary disease and comments on an article by Shen, et al., published, in 2018, in the Journal of Palliative Care, entitled “Life-sustaining procedures, palliative care consultation, and do-not resuscitate status in dying patients with COPD in US hospitals: 2010-2014.”
AHRQ-funded; HS023009.
Citation: Iyer AS, Benzo RP, Bakitas MA .
Easing the tension between palliative care and intensive care in chronic obstructive pulmonary disease.
J Palliat Care 2018 Jul;33(3):123-24. doi: 10.1177/0825859718782505..
Keywords: Chronic Conditions, Respiratory Conditions, Critical Care, Elderly, Palliative Care, Quality of Care
Wei YJ, Simoni-Wastila L, Albrecht JS
The association of antidepressant treatment with COPD maintenance medication use and adherence in a comorbid Medicare population: a longitudinal cohort study.
Researchers examined the association between antidepressant treatment and use of and adherence to chronic obstructive pulmonary disease (COPD) maintenance medications among patients with new-onset COPD and comorbid depression. They concluded that regularly treated depression may increase use of and adherence to necessary maintenance medications for COPD.
AHRQ-funded; HS024560.
Citation: Wei YJ, Simoni-Wastila L, Albrecht JS .
The association of antidepressant treatment with COPD maintenance medication use and adherence in a comorbid Medicare population: a longitudinal cohort study.
Int J Geriatr Psychiatry 2018 Feb;33(2):e212-e20. doi: 10.1002/gps.4772.
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Keywords: Medication, Respiratory Conditions, Elderly, Patient Adherence/Compliance
Albrecht JS, Khokhar B, Huang TY
Adherence and healthcare utilization among older adults with COPD and depression.
The researchers quantified the independent effects of adherence to antidepressants and chronic obstructive pulmonary disease (COPD) maintenance medications on healthcare utilization among individuals co-diagnosed with COPD and depression. They found that, compared to no use,higher levels of adherence to COPD maintenance medications were associated with decreased risk of ED visits and hospitalizations. Similarly, higher levels of adherence to antidepressants resulted in decreased risk of ED visits and hospitalization.
AHRQ-funded; HS024560.
Citation: Albrecht JS, Khokhar B, Huang TY .
Adherence and healthcare utilization among older adults with COPD and depression.
Respir Med 2017 Aug;129:53-58. doi: 10.1016/j.rmed.2017.06.002.
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Keywords: Elderly, Healthcare Utilization, Respiratory Conditions, Depression, Patient Adherence/Compliance
Sinha SS, Sjoding MW, Sukul D
Changes in primary noncardiac diagnoses over time among elderly cardiac intensive care unit patients in the United States.
This study examined changes in primary noncardiac diagnoses among elderly patients admitted to a cardiac intensive care unit (CICU) during the past decade. More than half of all elderly patients with a CICU stay across the United States now have primary noncardiac diagnoses at discharge. These patients receive different types of care and have worse outcomes than patients with primary cardiac diagnoses.
AHRQ-funded; HS020672.
Citation: Sinha SS, Sjoding MW, Sukul D .
Changes in primary noncardiac diagnoses over time among elderly cardiac intensive care unit patients in the United States.
Circ Cardiovasc Qual Outcomes 2017 Aug;10(8):e003616. doi: 10.1161/circoutcomes.117.003616.
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Keywords: Elderly, Heart Disease and Health, Intensive Care Unit (ICU), Outcomes, Respiratory Conditions
Albrecht JS, Park Y, Hur P
Adherence to maintenance medications among older adults with chronic obstructive pulmonary disease. the role of depression.
The objective of this study was to assess the impact of depression on COPD maintenance medication adherence among of Medicare beneficiaries newly diagnosed with COPD. Average monthly adherence to COPD maintenance medications was low, peaking at 57 percent in the month after first fill and decreasing to 35 percent within 6 months. In the adjusted regression model, depression was associated with decreased adherence to COPD maintenance medications.
AHRQ-funded; HS024560.
Citation: Albrecht JS, Park Y, Hur P .
Adherence to maintenance medications among older adults with chronic obstructive pulmonary disease. the role of depression.
Ann Am Thorac Soc 2016 Sep;13(9):1497-504. doi: 10.1513/AnnalsATS.201602-136OC.
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Keywords: Respiratory Conditions, Elderly, Medication, Patient Adherence/Compliance, Depression
Nishi SP, Zhang W, Kuo YF
Pulmonary rehabilitation utilization in older adults with chronic obstructive pulmonary disease, 2003 to 2012.
The authors assessed the trends in pulmonary rehabilitation (PR) utilization and factors associated with its use in older adults with chronic obstructive pulmonary disease (COPD). They concluded that utilization of PR during the study period increased only 1.1% in these Medicare beneficiaries with COPD and remained low.
AHRQ-funded; HS020642; HS022134.
Citation: Nishi SP, Zhang W, Kuo YF .
Pulmonary rehabilitation utilization in older adults with chronic obstructive pulmonary disease, 2003 to 2012.
J Cardiopulm Rehabil Prev 2016 Sep-Oct;36(5):375-82. doi: 10.1097/hcr.0000000000000194.
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Keywords: Respiratory Conditions, Elderly, Patient-Centered Outcomes Research, Rehabilitation
Hasegawa K, Camargo CA, Jr.
Prevalence of blood eosinophilia in hospitalized patients with acute exacerbation of COPD.
In this first study to investigate the prevalence of eosinophilia among inpatients with acute exacerbation of COPD, the authors found that 17% had blood eosinophilia, and that such patients had higher frequency of readmission during a one-year follow-up period.
AHRQ-funded; HS023305.
Citation: Hasegawa K, Camargo CA, Jr. .
Prevalence of blood eosinophilia in hospitalized patients with acute exacerbation of COPD.
Respirology 2016 May;21(4):761-4. doi: 10.1111/resp.12724.
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Keywords: Respiratory Conditions, Elderly, Hospitalization, Outcomes, Hospital Readmissions
Bell ML, Son JY, Peng RD
Ambient PM2.5 and risk of hospital admissions: do risks differ for men and women?
The researchers conducted a multi-site time-series analysis of short-term fine particulate matter (PM) exposure and cardiovascular and respiratory hospital admissions among older persons to examine whether effects differ by sex. They found that women may be more susceptible to PM2.5-related hospitalizations for some respiratory and cardiovascular causes.
AHRQ-funded; HS021991.
Citation: Bell ML, Son JY, Peng RD .
Ambient PM2.5 and risk of hospital admissions: do risks differ for men and women?
Epidemiology 2015 Jul;26(4):575-9. doi: 10.1097/ede.0000000000000310..
Keywords: Elderly, Hospitalization, Respiratory Conditions, Cardiovascular Conditions
Shah T, Churpek MM, Coca Perraillon M
Understanding why patients with COPD get readmitted: a large national study to delineate the Medicare population for the readmissions penalty expansion.
The Hospital Readmissions Reduction Program (HRRP) penalizes hospitals for 30-day readmissions and was extended to COPD in October 2014. The authors investigated readmission risk factors and reasons for readmission in order to guide hospitals in initiating programs to reduce COPD readmissions. They found that patients discharged home without home care were more likely to be readmitted for COPD than patients discharged to post-acute care, and those readmitted were more likely to be dually enrolled in Medicare and Medicaid, have a longer median length of stay, and have more comorbidities. They concluded that the addition of COPD to the readmissions penalty may further worsen the disproportionately high penalties seen in safety net hospitals.
AHRQ-funded; HS021877.
Citation: Shah T, Churpek MM, Coca Perraillon M .
Understanding why patients with COPD get readmitted: a large national study to delineate the Medicare population for the readmissions penalty expansion.
Chest 2015 May;147(5):1219-26. doi: 10.1378/chest.14-2181.
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Keywords: Respiratory Conditions, Elderly, Medicare, Hospital Readmissions
Sharma G, Meena R, Goodwin JS
Burn injury associated with home oxygen use in patients with chronic obstructive pulmonary disease.
The researchers quantified the risk of burn injury associated with home oxygen use and examined the risk factors associated with the development of this injury. They found that the absolute risk of burn injury in patients prescribed oxygen therapy was 2.98 per 1000 patients compared with 1.69 per 1000 patients not prescribed oxygen during a 22-month period.
AHRQ-funded; HS020642; HS022134.
Citation: Sharma G, Meena R, Goodwin JS .
Burn injury associated with home oxygen use in patients with chronic obstructive pulmonary disease.
Mayo Clin Proc 2015 Apr;90(4):492-9. doi: 10.1016/j.mayocp.2014.12.024..
Keywords: Injuries and Wounds, Adverse Events, Risk, Respiratory Conditions, Elderly
Nishi SP, Zhang W, Kuo YF
Oxygen therapy use in older adults with chronic obstructive pulmonary disease.
The researchers examined national trends and factors associated with the use of oxygen therapy and sustained oxygen therapy in older adults with COPD between 2001 and 2010. They found an increase in oxygen therapy use but a decrease in sustained oxygen therapy in fee-for-service Medicare beneficiaries with COPD from 2001 to 2010.
AHRQ-funded; HS022134; HS020642.
Citation: Nishi SP, Zhang W, Kuo YF .
Oxygen therapy use in older adults with chronic obstructive pulmonary disease.
PLoS One 2015 Mar 18;10(3):e0120684. doi: 10.1371/journal.pone.0120684..
Keywords: Elderly, Medicare, Respiratory Conditions
Shear TC, Balachandran JS, Mokhlesi B
Risk of sleep apnea in hospitalized older patients.
This study assessed the prevalence of undiagnosed obstructive sleep apnea (OSA) among general medical inpatients and to investigate whether OSA risk is associated with in-hospital sleep quantity and quality. It found that two of every 5 inpatients older than 50 years screened at high risk for OSA. Those screening at high risk have worse in-hospital sleep quantity and quality.
AHRQ-funded; HS016967.
Citation: Shear TC, Balachandran JS, Mokhlesi B .
Risk of sleep apnea in hospitalized older patients.
J Clin Sleep Med 2014 Oct 15;10(10):1061-6. doi: 10.5664/jcsm.4098..
Keywords: Elderly, Sleep Problems, Risk, Respiratory Conditions