National Healthcare Quality and Disparities Report
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
26 to 45 of 45 Research Studies Displayedde Cordova PB, Johansen ML, Martinez ME
Emergency department weekend presentation and mortality in patients with acute myocardial infarction.
The purpose of this research was to determine if weekend and holiday presentation is associated with increased mortality in EDs among patients with acute myocardial infarction (AMI) in New Jersey. It found that weekend/holiday presentation to the ED for AMI was associated with increased mortality. The effect may be related to the limited availability of resources on weekend/holidays compared to weekdays.
AHRQ-funded; HS024339.
Citation: de Cordova PB, Johansen ML, Martinez ME .
Emergency department weekend presentation and mortality in patients with acute myocardial infarction.
Nurs Res 2017 Jan/Feb;66(1):20-27. doi: 10.1097/nnr.0000000000000196.
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Keywords: Emergency Medical Services (EMS), Emergency Department, Mortality, Heart Disease and Health, Risk
Salinas JL, Rentsch C, Marconi VC
Baseline, time-updated, and cumulative HIV care metrics for predicting acute myocardial infarction and all-cause mortality.
The researchers studied prediction rates of myocardial infarction in those with HIV. They found that the Veterans Aging Cohort Study (VACS) Index provided better acute myocardial infarction and mortality prediction than CD4 count and HIV-1 RNA, concluding that current health determines risk more accurately than prior history.
AHRQ-funded; HS018372.
Citation: Salinas JL, Rentsch C, Marconi VC .
Baseline, time-updated, and cumulative HIV care metrics for predicting acute myocardial infarction and all-cause mortality.
Clin Infect Dis 2016 Dec 1;63(11):1423-30. doi: 10.1093/cid/ciw564.
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Keywords: Human Immunodeficiency Virus (HIV), Mortality, Heart Disease and Health, Risk
Durstenfeld MS, Ogedegbe O, Katz SD
Racial and ethnic differences in heart failure readmissions and mortality in a large municipal healthcare system.
This study sought to determine whether racial and ethnic differences exist among patients with similar access to care. It examined outcomes after heart failure hospitalization within a large municipal health system and determined that racial and ethnic differences in outcomes were present.
AHRQ-funded; HS023683.
Citation: Durstenfeld MS, Ogedegbe O, Katz SD .
Racial and ethnic differences in heart failure readmissions and mortality in a large municipal healthcare system.
JACC Heart Fail 2016 Nov;4(11):885-93. doi: 10.1016/j.jchf.2016.05.008.
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Keywords: Heart Disease and Health, Hospital Readmissions, Hospitalization, Mortality, Outcomes, Racial and Ethnic Minorities
Mukherjee JT, Beshansky JR, Ruthazer R
In-hospital measurement of left ventricular ejection fraction and one-year outcomes in acute coronary syndromes: results from the IMMEDIATE Trial.
The relationships between reduced left ventricular ejection fraction (LVEF) measured during index acute coronary syndrome (ACS) hospitalization and mortality and heart failure (HF) within 1 year are not well-defined. The researchers performed a retrospective analysis of 445 patients who had LVEF measured by left ventriculography or echocardiogram during hospitalization. They found that among patients with ACS, lower in-hospital LVEF is associated with increased 1-year mortality or hospitalization for HF.
AHRQ-funded; HS000060.
Citation: Mukherjee JT, Beshansky JR, Ruthazer R .
In-hospital measurement of left ventricular ejection fraction and one-year outcomes in acute coronary syndromes: results from the IMMEDIATE Trial.
Cardiovasc Ultrasound 2016 Aug 3;14(1):29. doi: 10.1186/s12947-016-0068-1.
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Keywords: Cardiovascular Conditions, Care Management, Heart Disease and Health, Mortality, Outcomes
Wang Y, Eldridge N, Metersky ML
AHRQ Author: Eldridge N
Association between hospital performance on patient safety and 30-day mortality and unplanned readmission for Medicare fee-for-service patients with acute myocardial infarction.
The researchers studied the relationship between hospital performance on adverse event rates and hospital performance on 30-day mortality and unplanned readmission rates for Medicare fee-for-service patients hospitalized for acute myocardial infarction (AMI). They found that for Medicare fee-for-service patients discharged with AMI, hospitals with poorer patient safety performance were also more likely to have poorer performance on 30-day all-cause mortality and on unplanned readmissions.
AHRQ-authored.
Citation: Wang Y, Eldridge N, Metersky ML .
Association between hospital performance on patient safety and 30-day mortality and unplanned readmission for Medicare fee-for-service patients with acute myocardial infarction.
J Am Heart Assoc 2016 Jul;5(7):pii: e003731. doi: 10.1161/jaha.116.003731.
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Keywords: Adverse Events, Hospital Readmissions, Hospitals, Medicare, Mortality, Heart Disease and Health, Patient Safety, Provider Performance
Chen J, Hsieh AF, Dharmarajan K
National trends in heart failure hospitalization after acute myocardial infarction for Medicare beneficiaries: 1998-2010.
This study used a complete national sample of 2 789 943 AMI hospitalizations of Medicare fee-for-service beneficiaries from 1998 through 2010, we evaluated annual changes in the incidence of subsequent heart failure (HF) hospitalization and mortality using Poisson and survival analysis models. It found that HF hospitalization after AMI decreased from 1998 to 2010, which may indicate improvements in the management of AMI.
AHRQ-funded; HS018781.
Citation: Chen J, Hsieh AF, Dharmarajan K .
National trends in heart failure hospitalization after acute myocardial infarction for Medicare beneficiaries: 1998-2010.
Circulation 2013 Dec 17;128(24):2577-84. doi: 10.1161/circulationaha.113.003668..
Keywords: Hospitalization, Medicare, Heart Disease and Health, Mortality
Spatz ES, Beckman AL, Wang Y
Geographic variation in trends and disparities in acute myocardial infarction hospitalization and mortality by income levels, 1999-2013.
The researchers sought to determine whether trends in US county-level, risk-standardized acute myocardial infarction (AMI) hospitalization and mortality rates varied by county-based median income level. They concluded that hospitalization and mortality rates of AMI declined among counties of all income levels, although hospitalization rates among low-income counties lag behind those of the higher income groups.
AHRQ-funded; HS023000.
Citation: Spatz ES, Beckman AL, Wang Y .
Geographic variation in trends and disparities in acute myocardial infarction hospitalization and mortality by income levels, 1999-2013.
JAMA Cardiol 2016 Jun 1;1(3):255-65. doi: 10.1001/jamacardio.2016.0382.
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Keywords: Disparities, Hospitalization, Heart Disease and Health, Mortality, Social Determinants of Health
Blecker S, Park H, Katz SD
Association of HbA1c with hospitalization and mortality among patients with heart failure and diabetes.
Comorbid diabetes is common in heart failure and associated with increased hospitalization and mortality. Nonetheless, the association between glycemic control and outcomes among patients with heart failure and diabetes remains poorly characterized, particularly among low income and minority patients. This study found that among a cohort of primarily minority and low income patients with heart failure and diabetes, an increased risk of hospitalization was observed.
AHRQ-funded; HS023683.
Citation: Blecker S, Park H, Katz SD .
Association of HbA1c with hospitalization and mortality among patients with heart failure and diabetes.
BMC Cardiovasc Disord 2016 May 20;16:99. doi: 10.1186/s12872-016-0275-6.
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Keywords: Diabetes, Heart Disease and Health, Mortality, Hospitalization, Racial and Ethnic Minorities
Brown JR, Rezaee ME, Nichols EL
Incidence and in-hospital mortality of acute kidney injury (AKI) and dialysis-requiring AKI (AKI-D) after cardiac catheterization in the National Inpatient Sample.
This study examined cardiac catheterization or percutaneous coronary intervention (PCI) hospital discharges from the nationally representative National Inpatient Sample to determine annual population incidence rates for AKI and AKI-D in the United States from 2001 to 2011. It found that the incidence of AKI among cardiac catheterization and PCI patients has increased sharply in the United States; however, mortality has significantly declined.
AHRQ-funded; HS018443.
Citation: Brown JR, Rezaee ME, Nichols EL .
Incidence and in-hospital mortality of acute kidney injury (AKI) and dialysis-requiring AKI (AKI-D) after cardiac catheterization in the National Inpatient Sample.
J Am Heart Assoc 2016 Mar 15;5(3):e002739. doi: 10.1161/jaha.115.002739.
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Keywords: Healthcare Cost and Utilization Project (HCUP), Adverse Events, Mortality, Patient Safety, Surgery, Heart Disease and Health, Cardiovascular Conditions, Kidney Disease and Health, Dialysis, Hospitals
Hollis RH, Singletary BA, McMurtrie JT
Blood transfusion and 30-day mortality in patients with coronary artery disease and anemia following noncardiac surgery.
The researchers evaluated the association between postoperative blood transfusion and mortality in patients with coronary artery disease and postoperative MI following noncardiac surgery. Their findings support a restrictive postoperative transfusion strategy in patients with stable coronary artery disease following noncardiac surgery.
AHRQ-funded; HS013852.
Citation: Hollis RH, Singletary BA, McMurtrie JT .
Blood transfusion and 30-day mortality in patients with coronary artery disease and anemia following noncardiac surgery.
JAMA Surg 2016 Feb;151(2):139-45. doi: 10.1001/jamasurg.2015.3420.
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Keywords: Mortality, Surgery, Heart Disease and Health, Patient-Centered Outcomes Research
Zeitler EP, Hellkamp AS, Schulte PJ
Comparative effectiveness of implantable cardioverter defibrillators for primary prevention in women.
The researchers examined clinical practice data to compare survival rates among women with heart failure with or without a primary prevention implantable cardioverter defibrillator (ICD). Theyn found that among patients with heart failure with reduced left ventricular ejection fraction, a primary prevention ICD was associated with a significant survival advantage among women and among men.
AHRQ-funded; HS021092.
Citation: Zeitler EP, Hellkamp AS, Schulte PJ .
Comparative effectiveness of implantable cardioverter defibrillators for primary prevention in women.
Circ Heart Fail 2016 Jan;9(1):e002630. doi: 10.1161/circheartfailure.115.002630.
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Keywords: Medical Devices, Comparative Effectiveness, Prevention, Heart Disease and Health, Mortality
Lim E, Cheng Y, Reuschel C
Risk-adjusted in-hospital mortality models for congestive heart failure and acute myocardial infarction: Value of clinical laboratory data and race/ethnicity.
This study examined the impact of key laboratory and race/ethnicity data on the prediction of in-hospital mortality for congestive heart failure (CHF) and acute myocardial infarction (AMI). It found that adding a simple three-level summary measure based on the number of abnormal laboratory data observed to hospital administrative claims data significantly improved the model prediction for inpatient mortality.
AHRQ-funded; HS019990.
Citation: Lim E, Cheng Y, Reuschel C .
Risk-adjusted in-hospital mortality models for congestive heart failure and acute myocardial infarction: Value of clinical laboratory data and race/ethnicity.
Health Serv Res 2015 Aug;50 Suppl 1:1351-71. doi: 10.1111/1475-6773.12325..
Keywords: Heart Disease and Health, Mortality, Data, Inpatient Care
Kabra R, Cram P, Girotra S
Effect of race on outcomes (stroke and death) in patients >65 years with atrial fibrillation.
The researchers sought to determine whether there are any racial differences in the outcomes of death and stroke in patients with newly diagnosed AF in patients >65 years. They found that the risks of death and stroke are higher in blacks and Hispanics compared with whites. The increased risk was eliminated or significantly reduced after adjusting for preexisting co-morbidities.
AHRQ-funded; HS021992.
Citation: Kabra R, Cram P, Girotra S .
Effect of race on outcomes (stroke and death) in patients >65 years with atrial fibrillation.
Am J Cardiol 2015 Jul 15;116(2):230-5. doi: 10.1016/j.amjcard.2015.04.012..
Keywords: Elderly, Heart Disease and Health, Cardiovascular Conditions, Racial and Ethnic Minorities, Stroke, Mortality, Risk
Qian F, Hannan EL, Pine M
Can adding laboratory values improve risk-adjustment mortality models using clinical percutaneous cardiac intervention registry data?
The authors predicted in-hospital/30-day mortality with and without appended laboratory data using New York's percutaneous coronary intervention registry data from 2008-2010. They found that adding laboratory data did not significantly improve the risk-adjustment mortality models' performance and did not dramatically change the quality assessment of hospitals.
AHRQ-funded; HS019965.
Citation: Qian F, Hannan EL, Pine M .
Can adding laboratory values improve risk-adjustment mortality models using clinical percutaneous cardiac intervention registry data?
J Invasive Cardiol 2015 Jul;27(7):E117-24.
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Keywords: Heart Disease and Health, Mortality, Registries, Risk
Lopes RD, Gharacholou SM, Holmes DN
Cumulative incidence of death and rehospitalization among the elderly in the first year after NSTEMI.
The researchers evaluated mortality and cause-specific rehospitalization rates in elderly non-ST-segment elevation myocardial infarction survivors with ischemic heart disease. They found that rehospitalization rates do not rise substantially with advancing age, and rehospitalization is often for noncardiac diagnoses.
AHRQ-funded; HS021092.
Citation: Lopes RD, Gharacholou SM, Holmes DN .
Cumulative incidence of death and rehospitalization among the elderly in the first year after NSTEMI.
Am J Med 2015 Jun;128(6):582-90. doi: 10.1016/j.amjmed.2014.12.032.
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Keywords: Elderly, Mortality, Heart Disease and Health, Cardiovascular Conditions, Hospital Readmissions
Goldman LE, Chu PW, Bacchetti P
Effect of present-on-admission (POA) reporting accuracy on hospital performance assessments using risk-adjusted mortality.
This study evaluated how the accuracy of present-on-admission (POA) reporting affects hospital 30-day acute myocardial infarction (AMI) mortality assessments. It finds that the use of POA indicators in administrative data significantly alters risk-adjusted hospital assessments that do not incorporate a method for distinguishing between comorbidities and complications.
AHRQ-funded; HS018090.
Citation: Goldman LE, Chu PW, Bacchetti P .
Effect of present-on-admission (POA) reporting accuracy on hospital performance assessments using risk-adjusted mortality.
Health Serv Res 2015 Jun;50(3):922-38. doi: 10.1111/1475-6773.12239.
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Keywords: Hospitals, Mortality, Heart Disease and Health, Quality Indicators (QIs)
Lo AX, Donnelly JP, McGwin G
Impact of gait speed and instrumental activities of daily living on all-cause mortality in adults >/=65 years with heart failure.
This study investigated the impact of gait speed and IADL, separately and combined, on all-cause mortality in adults with incident heart failure who are >65 years. It found that the combined presence of slower gait speed and Instrumental Activities of Daily Living (IADL) impairment was associated with a greater risk of mortality and suggested an additive relation between gait speed and IADL.
AHRQ-funded; HS013852.
Citation: Lo AX, Donnelly JP, McGwin G .
Impact of gait speed and instrumental activities of daily living on all-cause mortality in adults >/=65 years with heart failure.
Am J Cardiol 2015 Mar 15;115(6):797-801. doi: 10.1016/j.amjcard.2014.12.044..
Keywords: Elderly, Heart Disease and Health, Mortality
Alcantara C, Muntner P, Edmondson D
Perfect storm: concurrent stress and depressive symptoms increase risk of myocardial infarction or death.
A recently offered psychosocial perfect storm conceptual model hypothesizes amplified risk will occur in those with concurrent stress and depressive symptoms. The authors tested this hypothesis in a large sample of US adults with coronary heart disease. They found that those with low stress and high depressive symptoms or high stress and low depressive symptoms were not at increased risk, while participants with concurrent high stress and high depressive symptoms had increased risk for myocardial infarction or death relative to those with low stress and low depressive symptoms. They concluded that their results provide initial support for a psychosocial perfect storm conceptual model.
AHRQ-funded; HS023009.
Citation: Alcantara C, Muntner P, Edmondson D .
Perfect storm: concurrent stress and depressive symptoms increase risk of myocardial infarction or death.
Circ Cardiovasc Qual Outcomes 2015 Mar;8(2):146-54. doi: 10.1161/circoutcomes.114.001180.
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Keywords: Depression, Heart Disease and Health, Mortality, Risk, Stress
Conlon TW, Falkensammer CB, Hammond RS
Association of left ventricular systolic function and vasopressor support with survival following pediatric out-of-hospital cardiac arrest.
This study characterizes the association of hospital discharge survival with left ventricular systolic function evaluated by transthoracic echocardiography and vasoactive infusion support following return of spontaneous circulation after pediatric out-of-hospital cardiac arrest. It found that in patients receiving transthoracic echocardiography within the first 24 hours, decreased left ventricular systolic function and vasopressor use were common.
AHRQ-funded; HS022464.
Citation: Conlon TW, Falkensammer CB, Hammond RS .
Association of left ventricular systolic function and vasopressor support with survival following pediatric out-of-hospital cardiac arrest.
Pediatr Crit Care Med 2015 Feb;16(2):146-54. doi: 10.1097/pcc.0000000000000305..
Keywords: Children/Adolescents, Hospital Discharge, Mortality, Heart Disease and Health
Chaudhry SI, Khan RF, Chen J
National trends in recurrent AMI hospitalizations 1 year after acute myocardial infarction in Medicare beneficiaries: 1999-2010.
The investigators evaluated changes in the incidence of 1-year recurrent acute myocardial infarction (AMI) hospitalization and mortality. In a national sample of Medicare beneficiaries hospitalized for AMI from 1999 to 2010, they found that hospitalization for recurrent AMI decreased, as did subsequent mortality, albeit to a lesser extent. The risk of recurrent AMI hospitalization declined less in black patients than in whites, increasing observed racial disparities by the end of the study period.
AHRQ-funded; HS018781.
Citation: Chaudhry SI, Khan RF, Chen J .
National trends in recurrent AMI hospitalizations 1 year after acute myocardial infarction in Medicare beneficiaries: 1999-2010.
J Am Heart Assoc 2014 Oct;3(5):e001197. doi: 10.1161/jaha.114.001197.
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Keywords: Hospitalization, Medicare, Mortality, Heart Disease and Health, Risk