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AHRQ Research Studies Date
Topics
- Behavioral Health (2)
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- (-) Patient-Centered Outcomes Research (13)
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- Patient Self-Management (2)
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- Racial and Ethnic Minorities (1)
- Sexual Health (1)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 13 of 13 Research Studies DisplayedKorthuis PT, Cook RR, Lum PJ
HIV clinic-based extended-release naltrexone versus treatment as usual for people with HIV and opioid use disorder: a non-blinded, randomized non-inferiority trial.
Opioid Use Disorder (OUD) treatment medications can improve outcomes for human immunodeficiency virus (HIV) and also reduce opioid use. The purpose of the study was to determine if outpatient naltrexone treatment could also reduce opioid use and improve outcomes for HIV. The researchers reported that enrollment was stopped early because of slower than expected recruitment, resulting in 114 final participants with untreated OUD and HIV, with 62% positive for fentanyl, 60% positive for cocaine, and 47% positive for other opioids at the baseline. The intervention compared treatment as usual (TAU) of methadone or buprenorphine with extended-release naltrexone (XR-NTX) on group differences in viral suppression at 24 weeks and past 30-day use of opioids at 24 weeks. The study reported that at 24 weeks the outcome of viral suppression was similar for TAU and XR-NTX, and that fewer XR-NTX participants initiated medication than TAU participants. The outcome of previous 30-day use of opioids was similar for TAU as compared to XR-NTX. Of those participants who did initiate medication, those administered XR-NTX experienced less days of opioid use when compared with TAU in the prior 30 days. The researchers reported that the study evidence was not conclusive but did support that XR-NTX is not inferior to TAU for HIV viral suppression, and that study participants who started XR-NTX used less opioids at 24 weeks than participants who were administered TAU.
AHRQ-funded; HS026370.
Citation: Korthuis PT, Cook RR, Lum PJ .
HIV clinic-based extended-release naltrexone versus treatment as usual for people with HIV and opioid use disorder: a non-blinded, randomized non-inferiority trial.
Addiction 2022 Jul;117(7):1961-71. doi: 10.1111/add.15836..
Keywords: Human Immunodeficiency Virus (HIV), Opioids, Substance Abuse, Behavioral Health, Medication, Treatments, Patient-Centered Outcomes Research, Outcomes, Evidence-Based Practice
Fredericksen RJ, Harding BN, Ruderman SA
Patient acceptability and usability of a self-administered electronic patient-reported outcome assessment in HIV care: relationship with health behaviors and outcomes.
The authors assessed acceptability/usability of tablet-based patient-reported outcome (PRO) assessments among patients in HIV care and relationships with health outcomes using a modified Acceptability E-Scale (AES) within a self-administered PRO assessment. They found that higher acceptability was associated with better quality of life and adherence while lower acceptability was associated with higher depression symptoms, recent illicit opioid use, and multiple recent sex partners. While patients endorsing depression symptoms, recent opioid use, sex without condoms, or multiple sex partners found PROs less acceptable, overall, patients found the assessments highly acceptable and easy to use.
AHRQ-funded; HS026154.
Citation: Fredericksen RJ, Harding BN, Ruderman SA .
Patient acceptability and usability of a self-administered electronic patient-reported outcome assessment in HIV care: relationship with health behaviors and outcomes.
AIDS Care 2021 Sep;33(9):1167-77. doi: 10.1080/09540121.2020.1845288..
Keywords: Human Immunodeficiency Virus (HIV), Quality of Life, Patient-Centered Outcomes Research, Outcomes, Chronic Conditions
Nijhawan AE, Bhattatiry M, Chansard M
HIV care cascade before and after hospitalization: impact of a multidisciplinary inpatient team in the US South.
Hospitalization represents an opportunity to re-engage out-of-care individuals, improve HIV outcomes, and reduce health disparities. The authors reviewed electronic health records of HIV-positive individuals hospitalized at an urban, public hospital between September 2013 and December 2015. They found that hospitalized patients with HIV had low rates of engagement in care, retention in care, and virologic suppression, though all three outcomes improved after hospitalization. A multidisciplinary transitions team improved care engagement and virologic suppression in those who received the intervention.
AHRQ-funded; HS022418.
Citation: Nijhawan AE, Bhattatiry M, Chansard M .
HIV care cascade before and after hospitalization: impact of a multidisciplinary inpatient team in the US South.
AIDS Care 2020 Nov;32(11):1343-52. doi: 10.1080/09540121.2019.1698704.
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Keywords: Human Immunodeficiency Virus (HIV), Transitions of Care, Inpatient Care, Teams, Hospitalization, Patient and Family Engagement, Patient-Centered Healthcare, Patient-Centered Outcomes Research, Outcomes, Evidence-Based Practice
Wang D
A comparison of in-person and online training in a statewide clinical education program for dissemination of HIV, HCV and STD clinical evidence.
This study compared in-person and online training for dissemination of clinical evidence of HIV, HCV, and STD. The study used 250 clinicians completing four training courses in dual formats over a three-month period. Online training was the preferred format by clinicians.
AHRQ-funded; HS022057.
Citation: Wang D .
A comparison of in-person and online training in a statewide clinical education program for dissemination of HIV, HCV and STD clinical evidence.
Stud Health Technol Inform 2019 Aug 21;264:2003-04. doi: 10.3233/shti190756..
Keywords: Human Immunodeficiency Virus (HIV), Hepatitis, Sexual Health, Evidence-Based Practice, Training, Patient-Centered Outcomes Research
Griffith DC, Farmer C, Gebo KA
Uptake and virological outcomes of single- versus multi-tablet antiretroviral regimens among treatment-naive youth in the HIV Research Network.
Researchers studied the impact of single-tablet regiments (STRs) versus multi-tablet regimens (MTRs) in the treatment of HIV with youth with HIV (YHIV) in the HIV Research Network between the ages of 13 and 24. The use of STRs was associated with greater compliance in their antiretroviral regiments and better outcomes over an 8-year period (2006-2014) at 18 US HIV clinical sites.
AHRQ-funded; 290201100007C.
Citation: Griffith DC, Farmer C, Gebo KA .
Uptake and virological outcomes of single- versus multi-tablet antiretroviral regimens among treatment-naive youth in the HIV Research Network.
HIV Med 2019 Feb;20(2):169-74. doi: 10.1111/hiv.12695..
Keywords: Children/Adolescents, Human Immunodeficiency Virus (HIV), Medication, Outcomes, Patient Adherence/Compliance, Patient-Centered Outcomes Research, Young Adults
Cho H, Porras T, Baik D
Understanding the predisposing, enabling, and reinforcing factors influencing the use of a mobile-based HIV management app: a real-world usability evaluation.
In this study, the authors conducted an in-depth analysis of users' experiences using an HIV self-management app. Usability evaluation in a real-world setting enabled the investigators to measure users' actual experiences when interacting with the app during their everyday lives. They suggest that their work highlighted the importance of using mobile technology for persons living with HIV, specifically those with low income/housing instability.
AHRQ-funded; HS023963.
Citation: Cho H, Porras T, Baik D .
Understanding the predisposing, enabling, and reinforcing factors influencing the use of a mobile-based HIV management app: a real-world usability evaluation.
Int J Med Inform 2018 Sep;117:88-95. doi: 10.1016/j.ijmedinf.2018.06.007..
Keywords: Health Information Technology (HIT), Human Immunodeficiency Virus (HIV), Patient-Centered Outcomes Research, Patient Self-Management
Saag LA, Tamhane AR, Batey DS
Mental health service utilization is associated with retention in care among persons living with HIV at a university-affiliated HIV clinic.
The researchers sought to determine if mental health (MH) service utilization would be associated with improved retention in care for patients with HIV and MH comorbidities. They concluded that even in the absence of documented MH comorbidities, improved retention in care was observed with increasing MH service utilization.
AHRQ-funded; HS023009.
Citation: Saag LA, Tamhane AR, Batey DS .
Mental health service utilization is associated with retention in care among persons living with HIV at a university-affiliated HIV clinic.
AIDS Res Ther 2018 Jan 16;15(1):1. doi: 10.1186/s12981-018-0188-9.
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Keywords: Healthcare Utilization, Human Immunodeficiency Virus (HIV), Behavioral Health, Patient-Centered Outcomes Research
Turan B, Hatcher AM, Weiser SD
Framing mechanisms linking HIV-related stigma, adherence to treatment, and health outcomes.
The authors present a conceptual framework that highlights how unique dimensions of individual-level HIV-related stigma (perceived community stigma, experienced stigma, internalized stigma, and anticipated stigma) might differently affect the health of those living with HIV. Their conceptual framework posits that, in the context of intersectional and structural stigmas, individual-level dimensions of HIV-related stigma operate through interpersonal factors, mental health, psychological resources, and biological stress pathways.
AHRQ-funded; HS013852.
Citation: Turan B, Hatcher AM, Weiser SD .
Framing mechanisms linking HIV-related stigma, adherence to treatment, and health outcomes.
Am J Public Health 2017 Jun;107(6):863-69. doi: 10.2105/ajph.2017.303744.
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Keywords: Human Immunodeficiency Virus (HIV), Medication, Patient Adherence/Compliance, Patient-Centered Outcomes Research, Social Stigma
Cho H, Iribarren S, Schnall R
Technology-mediated interventions and quality of life for persons living with HIV/AIDS. A systematic review.
The aim of this review was to assess the impact of technology-mediated interventions on quality of life (QoL) and to identify the instruments used to measure the QoL of persons living with HIV/AIDS (PLWH). It identified four types of technology-mediated interventions and two types of QoL instruments used to examine the impact of technology-mediated interventions on PLWH. However, the evidence to support the improvement of QoL using technology-mediated interventions was insufficient.
AHRQ-funded; HS023963.
Citation: Cho H, Iribarren S, Schnall R .
Technology-mediated interventions and quality of life for persons living with HIV/AIDS. A systematic review.
Appl Clin Inform 2017 Apr 12;8(2):348-68. doi: 10.4338/aci-2016-10-r-0175.
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Keywords: Evidence-Based Practice, Human Immunodeficiency Virus (HIV), Patient-Centered Outcomes Research, Quality of Life
Merlin JS, Bulls HW, Vucovich LA
Pharmacologic and non-pharmacologic treatments for chronic pain in individuals with HIV: a systematic review.
The authors conducted a systematic review to identify clinical trials and observational studies examining the impact of pharmacologic or non-pharmacologic interventions on pain and/or functional outcomes among HIV-infected individuals with chronic pain in high-development countries. They found that the only included controlled studies with positive results were of capsaicin and cannabis. Among the seven studies of pharmacologic interventions, the authors determined that five had substantial pharmaceutical industry sponsorship. Their findings highlight several important gaps in the HIV/chronic pain literature requiring further research.
AHRQ-funded; HS019465.
Citation: Merlin JS, Bulls HW, Vucovich LA .
Pharmacologic and non-pharmacologic treatments for chronic pain in individuals with HIV: a systematic review.
AIDS Care 2016 Dec;28(12):1506-15. doi: 10.1080/09540121.2016.1191612.
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Keywords: Chronic Conditions, Comparative Effectiveness, Human Immunodeficiency Virus (HIV), Medication, Patient-Centered Outcomes Research
Nijhawan AE, Kitchell E, Etherton SS
Half of 30-day hospital readmissions among HIV-infected patients are potentially preventable.
The researchers assessed whether readmissions among HIV-infected patients were potentially preventable using both published criteria and detailed chart review, how readmissions might have been prevented, and the phase of care deemed suboptimal (inpatient care, discharge planning, post-discharge). They found that among 130 individuals experiencing 30-day readmissions, about half were determined to be potentially preventable using published criteria (53 percent) or implicit chart review (48 percent).
AHRQ-funded; HS022418.
Citation: Nijhawan AE, Kitchell E, Etherton SS .
Half of 30-day hospital readmissions among HIV-infected patients are potentially preventable.
AIDS Patient Care STDS 2015 Sep;29(9):465-73. doi: 10.1089/apc.2015.0096..
Keywords: Human Immunodeficiency Virus (HIV), Hospital Readmissions, Electronic Health Records (EHRs), Patient-Centered Outcomes Research, Prevention
Merlin JS, Walcott M, Ritchie C
'Two pains together': patient perspectives on psychological aspects of chronic pain while living with HIV.
The researchers’ objective was to explore HIV-infected patients’ perspectives on psychological aspects of chronic pain using in-depth qualitative interviews. Key themes that emerged included the close relationship between mood and pain; mood and pain in the context of living with HIV; use of alcohol/drugs to self-medicate for pain; and the challenge of receiving prescription pain medications while dealing with substance use disorders.
AHRQ-funded; HS021694.
Citation: Merlin JS, Walcott M, Ritchie C .
'Two pains together': patient perspectives on psychological aspects of chronic pain while living with HIV.
PLoS One 2014 Nov 3;9(11):e111765. doi: 10.1371/journal.pone.0111765..
Keywords: Care Management, Chronic Conditions, Human Immunodeficiency Virus (HIV), Pain, Patient-Centered Outcomes Research, Patient Self-Management
Sentell T, Marten L, Ahn HJ
Disparities in hospitalizations among HIV positive individuals for native Hawaiians and Asians compared to whites in Hawaii.
This study investigated characteristics and disparities in hospitalizations among HIV positive individuals for Asian American subgroups and Native Hawaiians using data from all hospitalizations in Hawai‘i between December 2006 and December 2010. It concluded that disparities appear to exist in rates of hospitalizations among HIV positive individuals for Native Hawaiians and Asians, as well as in the demographic and, to some degree, the clinical characteristics of those hospitalized.
AHRQ-funded; HS019990.
Citation: Sentell T, Marten L, Ahn HJ .
Disparities in hospitalizations among HIV positive individuals for native Hawaiians and Asians compared to whites in Hawaii.
Hawaii J Med Public Health 2014 Oct;73(10):308-14..
Keywords: Hospitalization, Human Immunodeficiency Virus (HIV), Disparities, Racial and Ethnic Minorities, Patient-Centered Outcomes Research