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- Adverse Events (1)
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- Skin Conditions (1)
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- Social Determinants of Health (1)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 19 of 19 Research Studies DisplayedSoulsby WD, Lawson E, Okumura M
Socioeconomic factors are associated with severity of hospitalization in pediatric lupus: an analysis of the 2016 Kids' Inpatient Database.
This study’s goal was to investigate the relationship of income level and other socioeconomic factors with length of stay (LOS) in the hospital and severe lupus features using the 2016 Kids' Inpatient Database (KID). The cohort included children aged 2-20 identified with lupus hospitalization in the 2016 KID using International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10) codes (M32). A total of 3,367 unweighted lupus hospitalizations were identified. Income level was found to be a statistically significant predictor of increased LOS in the hospital for those in the lowest income quartile. Black race, "other" race, and public insurance were also associated with severe lupus features.
AHRQ-funded; HS026383.
Citation: Soulsby WD, Lawson E, Okumura M .
Socioeconomic factors are associated with severity of hospitalization in pediatric lupus: an analysis of the 2016 Kids' Inpatient Database.
Arthritis Care Res 2023 Oct; 75(10):2073-81. doi: 10.1002/acr.25121..
Keywords: Healthcare Cost and Utilization Project (HCUP), Children/Adolescents, Hospitalization, Chronic Conditions
Chovatiya R, Silverberg JI
Association of herpes zoster and chronic inflammatory skin disease in US inpatients.
The purpose of this study was to determine whether chronic inflammatory skin disease (CISD) is associated with herpes zoster (HZ). Data from the Nationwide Inpatient Sample 2002-2012 were analyzed. Findings showed that many CISDs are associated with increased hospitalization for HZ, even below the ages recommended for HZ vaccination. Recommendations included additional studies to establish CISD-specific vaccination guidelines.
AHRQ-funded; HS023011.
Citation: Chovatiya R, Silverberg JI .
Association of herpes zoster and chronic inflammatory skin disease in US inpatients.
J Am Acad Dermatol 2021 Dec;85(6):1437-45. doi: 10.1016/j.jaad.2019.12.073..
Keywords: Healthcare Cost and Utilization Project (HCUP), Skin Conditions, Chronic Conditions
Hirayama A, Goto T, Faridi MK
Association of obstructive sleep apnea with all-cause readmissions after hospitalization for asthma exacerbation in adults aged 18-54 years: a population-based study, 2010-2013.
The authors sought to investigate associations between obstructive sleep apnea (OSA) and readmission risk after hospitalization for asthma exacerbation using data from State Inpatient Databases from seven U.S. states. They found that, overall, OSA was associated with a significantly higher incident rate of all-cause readmission. Additionally, OSA was associated with higher incident rates of readmissions for five major diseases: asthma, COPD, respiratory failure, pneumonia, and congestive heart failure, compared to non-OSA.
AHRQ-funded; HS023305.
Citation: Hirayama A, Goto T, Faridi MK .
Association of obstructive sleep apnea with all-cause readmissions after hospitalization for asthma exacerbation in adults aged 18-54 years: a population-based study, 2010-2013.
J Asthma 2021 Sep;58(9):1176-85. doi: 10.1080/02770903.2020.1781887..
Keywords: Healthcare Cost and Utilization Project (HCUP), Sleep Problems, Hospital Readmissions, Asthma, Respiratory Conditions, Chronic Conditions
Lee K, Gani F, Canner JK
Racial disparities in utilization of palliative care among patients admitted with advanced solid organ malignancies.
The primary objective of this study was to describe racial differences in the use of inpatient palliative care consultations (IPCC) for patients with advanced cancer who are admitted to a hospital in the United States. Hospital admissions of patients with advanced cancers were identified through the National Inpatient Dataset. Findings showed that death during hospitalization was a significant modifier of the relationship between race and receipt of palliative care consultation. There were significant racial disparities in the utilization of IPCC for patients with advanced cancer.
AHRQ-funded; HS024736.
Citation: Lee K, Gani F, Canner JK .
Racial disparities in utilization of palliative care among patients admitted with advanced solid organ malignancies.
Am J Hosp Palliat Care 2021 Jun;38(6):539-46. doi: 10.1177/1049909120922779..
Keywords: Healthcare Cost and Utilization Project (HCUP), Palliative Care, Cancer, Disparities, Racial and Ethnic Minorities, Healthcare Utilization, Inpatient Care, Chronic Conditions
Singam V, Patel KR, Silverberg JI
Association of prurigo nodularis and lichen simplex chronicus with hospitalization for mental health disorders in US adults.
Prurigo nodularis (PN) and lichen simplex chronicus (LSC) are debilitating chronic pruritic diseases that can lead to and be exacerbated by psychosocial distress. However, little is known about the mental health (MH) comorbidities of PN/LSC. In this study, the investigators sought to evaluate the likelihood and cost-burden of MH comorbidities and emergencies associated with PN/LSC.
AHRQ-funded; HS023011.
Citation: Singam V, Patel KR, Silverberg JI .
Association of prurigo nodularis and lichen simplex chronicus with hospitalization for mental health disorders in US adults.
Arch Dermatol Res 2020 Oct;312(8):587-93. doi: 10.1007/s00403-020-02046-5..
Keywords: Healthcare Cost and Utilization Project (HCUP), Behavioral Health, Hospitalization, Chronic Conditions
Hirayama A, Goto T, Hasegawa K
Association of acute kidney injury with readmissions after hospitalization for acute exacerbation of chronic obstructive pulmonary disease: a population-based study.
This study examined the association between acute kidney injury (AKI) and readmission with hospitalization for acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Retrospective, population-based cohort data was used from the HCUP State Inpatient Databases from seven states (Arkansas, California, Florida, Iowa, Nebraska, New York, and Utah) from 2010 through 2013. A total of 356,990 patients were identified as hospitalized for AECOPD. Median age was 71 years and 41.9% were male. Of those 7% had a concurrent diagnosis of AKI. Patients with AKI were found to have a significantly higher risk of 30-day all-cause readmission compared to those without AKI as well as a significantly higher risk of 90-day all-cause readmission, particularly for non-respiratory reasons. These reasons included sepsis, acute renal failure, and congestive heart failure.
AHRQ-funded; HS023305.
Citation: Hirayama A, Goto T, Hasegawa K .
Association of acute kidney injury with readmissions after hospitalization for acute exacerbation of chronic obstructive pulmonary disease: a population-based study.
BMC Nephrol 2020 Apr 3;21(1):116. doi: 10.1186/s12882-020-01780-2..
Keywords: Healthcare Cost and Utilization Project (HCUP), Respiratory Conditions, Chronic Conditions, Hospital Readmissions, Hospitalization, Kidney Disease and Health
Goldstein E, Finelli L, O'Halloran A
AHRQ Author: Karaca Z, Steiner C
Hospitalizations associated with respiratory syncytial virus and influenza in children, including children diagnosed with asthma.
This study examined hospitalization rates in children associated with respiratory syncytial virus (RSV) and influenza, including children with asthma. HCUP hospitalization data and additional data to estimate RSV and influenza-associated hospitalization with a respiratory cause was analyzed in different subpopulations of US children between 2003 and 2010. Annual rates of RSV-associated hospitalization was highest in infants and young children, and declined rapidly with age. Influenza hospitalizations also were highest in young children and declined by age 12-17 years. Higher rates of RSV-related and influenza hospitalization in the youngest children with a prior diagnosis of asthma was also found.
AHRQ-authored.
Citation: Goldstein E, Finelli L, O'Halloran A .
Hospitalizations associated with respiratory syncytial virus and influenza in children, including children diagnosed with asthma.
Epidemiology 2019 Nov;30(6):918-26. doi: 10.1097/ede.0000000000001092..
Keywords: Healthcare Cost and Utilization Project (HCUP), Children/Adolescents, Asthma, Influenza, Respiratory Conditions, Hospitalization, Chronic Conditions
Phillips AZ, Rodriguez HP
Adults with diabetes residing in "food swamps" have higher hospitalization rates.
This study examined the relationship between ‘food swamps’ and hospitalization rates among adults with diabetes. Food Swamps are defined and measured by a ratio of fast food outlets to grocery stores within a given area. Data resources for this study included the Blue Cross Blue Shield Association Community Health Management Hub(R), AHRQ’s Health Care Cost and Utilization Project State Inpatient Databases, and HHS’s Area Health Resources File. The study concludes that higher hospitalization rates among adults with diabetes are significantly associated with food swamps, more so in rural than urban communities, and that improvements to local food environments may help to reduce this disparity.
AHRQ-funded; HS022241.
Citation: Phillips AZ, Rodriguez HP .
Adults with diabetes residing in "food swamps" have higher hospitalization rates.
Health Serv Res 2019 Feb;54(Suppl 1):217-25. doi: 10.1111/1475-6773.13102..
Keywords: Chronic Conditions, Diabetes, Disparities, Nutrition, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Social Determinants of Health
Ren Z, Narla S, Hsu DY
Association of serious infections with pemphigus and pemphigoid: analysis of the Nationwide Inpatient Sample.
The purpose of this study was to determine if the blistering disorders pemphigus and pemphigoid are associated with the increased likelihood of serious infections and with the impact of such infections on mortality and cost of care. Data from the 2002 - 2012 Nationwide Inpatient Sample was analyzed. The researchers conclude that adults with pemphigus or pemphigoid had increased infections - cutaneous, respiratory, multi-organ and systemic - associated with considerable inpatient mortality and cost burden. There were also significant clinical and healthcare disparities with respect to infections in patients with pemphigus or pemphigoid.
AHRQ-funded; HS023011.
Citation: Ren Z, Narla S, Hsu DY .
Association of serious infections with pemphigus and pemphigoid: analysis of the Nationwide Inpatient Sample.
J Eur Acad Dermatol Venereol 2018 Oct;32(10):1768-76. doi: 10.1111/jdv.14961..
Keywords: Chronic Conditions, Healthcare Cost and Utilization Project (HCUP)
Basu J, Hanchate A, Koroukian S
AHRQ Author: Basu, J
Multiple chronic conditions and disparities in 30-Day hospital readmissions among nonelderly adults.
This study examined the patterns of 30-day hospital readmissions by race/ethnicity and multiple chronic conditions (MCC) burden among nonelderly adult patients. The authors found considerable heterogeneity in levels of readmission risk among racial/ethnic subgroups stratified by chronic conditions. Among patients with a lowest MCC burden, African Americans had the highest risk of readmission, but with a higher MCC burden, the risk of readmission increased most for Hispanics.
AHRQ-authored.
Citation: Basu J, Hanchate A, Koroukian S .
Multiple chronic conditions and disparities in 30-Day hospital readmissions among nonelderly adults.
J Ambul Care Manage 2018 Oct/Dec;41(4):262-73. doi: 10.1097/jac.0000000000000246..
Keywords: Chronic Conditions, Disparities, Healthcare Cost and Utilization Project (HCUP), Hospital Readmissions, Racial and Ethnic Minorities
Hirayama A, Goto T, Shimada YJ
Acute exacerbation of chronic obstructive pulmonary disease and subsequent risk of emergency department visits and hospitalizations for atrial fibrillation.
Although emerging evidence has suggested the relationship of chronic obstructive pulmonary disease with atrial fibrillation (AF), little is known about whether acute exacerbation of chronic obstructive pulmonary disease (AECOPD) increases the risk of repeated AF-related healthcare utilization. The investigators found that among patients with existing AF, AECOPD was associated with a higher risk of AF-related ED visit or hospitalization in the first 90-day post-AECOPD period.
AHRQ-funded; HS023305.
Citation: Hirayama A, Goto T, Shimada YJ .
Acute exacerbation of chronic obstructive pulmonary disease and subsequent risk of emergency department visits and hospitalizations for atrial fibrillation.
Circ Arrhythm Electrophysiol 2018 Sep;11(9):e006322. doi: 10.1161/circep.118.006322..
Keywords: Healthcare Cost and Utilization Project (HCUP), Emergency Department, Respiratory Conditions, Heart Disease and Health, Cardiovascular Conditions, Chronic Conditions, Hospitalization, Risk, Healthcare Utilization
Goto T, Hirayama A, Faridi MK
Obesity and severity of acute exacerbation of chronic obstructive pulmonary disease.
A study was done to determine if there was an increase in severity and mortality with chronic obstructive pulmonary disease (COPD) patients who were also obese. Researchers used data from 2012-2013 State Inpatient Databases data of seven U.S. states. 17% of COPD patients in the database were defined as obese. Obesity was shown to increase use of ventilation, increased hospital stays but not in-hospital mortality.
AHRQ-funded; HS023305.
Citation: Goto T, Hirayama A, Faridi MK .
Obesity and severity of acute exacerbation of chronic obstructive pulmonary disease.
Ann Am Thorac Soc 2018 Feb;15(2):184-91. doi: 10.1513/AnnalsATS.201706-485OC..
Keywords: Chronic Conditions, Respiratory Conditions, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Mortality, Obesity
Berry JG, Ash AS, Cohen E
Contributions of children with multiple chronic conditions to pediatric hospitalizations in the United States: a retrospective cohort analysis.
Researchers assessed how much of US pediatric inpatient care is used by children with multiple chronic conditions (CMCC) and which chronic conditions are the key drivers of hospital use. CMCC accounted for over one-fourth of acute-care hospitalizations and one-half of all hospital dollars for US pediatric care in 2012. Substantial CMCC hospital resource use involves children with mental health-related conditions.
AHRQ-funded; HS023092.
Citation: Berry JG, Ash AS, Cohen E .
Contributions of children with multiple chronic conditions to pediatric hospitalizations in the United States: a retrospective cohort analysis.
Hosp Pediatr 2017 Jul;7(7):365-72. doi: 10.1542/hpeds.2016-0179.
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Keywords: Children/Adolescents, Chronic Conditions, Healthcare Cost and Utilization Project (HCUP), Healthcare Costs, Behavioral Health
Berry JG, Glotzbecker M, Rodean J
Comorbidities and complications of spinal fusion for scoliosis.
The researchers assessed the relationship between specific chronic conditions of children with medical complexity (CMC) and hospital resource use with spinal fusion for scoliosis, an operation with high cost and morbidity. They concluded that chronic respiratory insufficiency, bladder dysfunction, and epilepsy had significant associations with hospital resource use for CMC undergoing spinal fusion.
AHRQ-funded; HS024453.
Citation: Berry JG, Glotzbecker M, Rodean J .
Comorbidities and complications of spinal fusion for scoliosis.
Pediatrics 2017 Mar;139(3):e20162574. doi: 10.1542/peds.2016-2574.
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Keywords: Healthcare Cost and Utilization Project (HCUP), Children/Adolescents, Chronic Conditions, Adverse Events, Surgery
Stephens JR, Steiner MJ, DeJong N
Healthcare utilization and spending for constipation in children with versus without complex chronic conditions.
The aim of this retrospective cohort study was to examine the prevalence of diagnosis and treatment for constipation among children receiving Medicaid and to compare healthcare utilization and spending for constipation among children based on number of complex chronic conditions (CCCs). The investigators found that although the majority of pediatric constipation treatment occurred in the outpatient setting, inpatient care accounted for a sizable percentage of spending.
AHRQ-funded; HS023092.
Citation: Stephens JR, Steiner MJ, DeJong N .
Healthcare utilization and spending for constipation in children with versus without complex chronic conditions.
J Pediatr Gastroenterol Nutr 2017 Jan;64(1):31-36. doi: 10.1097/mpg.0000000000001210..
Keywords: Children/Adolescents, Chronic Conditions, Healthcare Costs, Healthcare Cost and Utilization Project (HCUP)
Gounder PP, Seeman SM, Holman RC
AHRQ Author: Steiner CA
Potentially preventable hospitalizations for acute and chronic conditions in Alaska, 2010-2012.
The Healthy Alaska 2020 initiative (HA2020) targeted reducing potentially preventable hospitalizations (PPH) for acute and chronic conditions among its health indicators. This study found that among 127,371 total hospitalizations, 4,911 and 6,721 were for acute and chronic PPH conditions, respectively. The overall crude PPH rate was 7.3 (3.1 for acute and 4.2 for chronic conditions).
AHRQ-authored.
Citation: Gounder PP, Seeman SM, Holman RC .
Potentially preventable hospitalizations for acute and chronic conditions in Alaska, 2010-2012.
Prev Med Rep 2016 Dec;4:614-21. doi: 10.1016/j.pmedr.2016.03.017.
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Keywords: Hospitalization, Healthcare Cost and Utilization Project (HCUP), Quality Indicators (QIs), Chronic Conditions, Quality of Care
Basu J, Avila R, Ricciardi R
AHRQ Author: Basu J, Ricciardi R
Hospital readmission rates in U.S. states: are readmissions higher where more patients with multiple chronic conditions cluster?
This study examines small area variations in readmission rates to assess whether higher readmission rate in an area is associated with higher clusters of patients with multiple chronic conditions. It found that areas with higher concentration of patients with increased comorbid conditions are more likely to have higher readmission rates.
AHRQ-authored.
Citation: Basu J, Avila R, Ricciardi R .
Hospital readmission rates in U.S. states: are readmissions higher where more patients with multiple chronic conditions cluster?
Health Serv Res 2016 Jun;51(3):1135-51. doi: 10.1111/1475-6773.12401..
Keywords: Chronic Conditions, Healthcare Cost and Utilization Project (HCUP), Hospital Readmissions, Hospitals
Skinner HG, Coffey R, Jones J
AHRQ Author: Heslin KC, Moy E
The effects of multiple chronic conditions on hospitalization costs and utilization for ambulatory care sensitive conditions in the United States: a nationally representative cross-sectional study.
A purpose of this study was to evaluate how multiple chronic conditions relate to inpatient hospitalization costs. It found that compared with costs for patients with 0 or 1 chronic condition, hospitalization costs per stay for overall ambulatory care sensitive conditions were 19 percent higher for those with 2 or 3 , 32 percent higher for those with 4 or 5, and 31 percent higher for those with 6+ conditions.
AHRQ-authored; AHRQ-funded; 290201300002C.
Citation: Skinner HG, Coffey R, Jones J .
The effects of multiple chronic conditions on hospitalization costs and utilization for ambulatory care sensitive conditions in the United States: a nationally representative cross-sectional study.
BMC Health Serv Res 2016 Mar 1;16:77. doi: 10.1186/s12913-016-1304-y.
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Keywords: Healthcare Cost and Utilization Project (HCUP), Chronic Conditions, Hospitalization, Healthcare Utilization, Healthcare Costs
Steiner CA, Friedman B
AHRQ Author: Steiner CA, Friedman B
Hospital utilization, costs, and mortality for adults with multiple chronic conditions, Nationwide Inpatient Sample, 2009.
The investigators provided a national estimate across all payers of the distribution and cost of selected chronic conditions for hospitalized adults in 2009, stratified by demographic characteristics. They found that there were approximately 28 million adult discharges from US hospitals other than those related to pregnancy and maternity; 39% had 2 to 3 multiple chronic conditions (MCC), and 33% had 4 or more. They concluded that their descriptive analysis of multipayer inpatient data provides a robust national view of the substantial use and costs among adults hospitalized with MCC.
AHRQ-authored.
Citation: Steiner CA, Friedman B .
Hospital utilization, costs, and mortality for adults with multiple chronic conditions, Nationwide Inpatient Sample, 2009.
Prev Chronic Dis 2013 Apr 25;10:E62. doi: 10.5888/pcd10.120292.
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Keywords: Chronic Conditions, Healthcare Costs, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Mortality