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Search All Research Studies
Topics
- Case Study (1)
- Children/Adolescents (3)
- Chronic Conditions (2)
- Electronic Health Records (EHRs) (1)
- Evidence-Based Practice (3)
- (-) Hepatitis (8)
- Medication (1)
- Patient Safety (1)
- Pregnancy (1)
- (-) Prevention (8)
- Public Health (1)
- Screening (6)
- Social Stigma (1)
- U.S. Preventive Services Task Force (USPSTF) (5)
- Vaccination (1)
- Vulnerable Populations (1)
- Women (1)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 8 of 8 Research Studies DisplayedWurcel AG, Reyes J, Zubiago J
"I'm not gonna be able to do anything about it, then what's the point?": A broad group of stakeholders identify barriers and facilitators to HCV testing in a Massachusetts jail.
Despite national guidelines promoting hepatitis C virus (HCV) testing in prisons, there is substantial heterogeneity on the implementation of HCV testing in jails. IN this study, the investigators sought to better understand barriers and opportunities for HCV testing by interviewing a broad group of stakeholders involved in HCV testing and treatment policies and procedures in Massachusetts jails.
AHRQ-funded; HS026008.
Citation: Wurcel AG, Reyes J, Zubiago J .
"I'm not gonna be able to do anything about it, then what's the point?": A broad group of stakeholders identify barriers and facilitators to HCV testing in a Massachusetts jail.
PLoS One 2021 May 26;16(5):e0250901. doi: 10.1371/journal.pone.0250901..
Keywords: Hepatitis, Vulnerable Populations, Screening, Prevention, Public Health, Social Stigma
Mabry-Hernandez I, O'Dowd N
AHRQ Author: Mabry-Hernandez I
Screening for hepatitis B virus infection in adolescents and adults.
This AHRQ-authored Putting Prevention Into Practice (PPIP) quiz is on the Hepatitis B virus (HBV) screening U.S. Preventive Services Task Force (USPSTF) recommendation. Only three questions are included with the answers at the end of the quiz. The questions are about 1) When to screen for HBV; 2) Who are the high-risk groups for HBV; and 3) Which country has the highest prevalence of HBV infection.
AHRQ-authored.
Citation: Mabry-Hernandez I, O'Dowd N .
Screening for hepatitis B virus infection in adolescents and adults.
Am Fam Physician 2021 Apr 15;103(8):493-94..
Keywords: U.S. Preventive Services Task Force (USPSTF), Children/Adolescents, Hepatitis, Screening, Prevention, Case Study
Chou R, Blazina I, Bougatsos C
Screening for hepatitis B virus infection in nonpregnant adolescents and adults: updated evidence report and systematic review for the US Preventive Services Task Force.
The authors updated the 2014 hepatitis B virus (HBV) screening review in nonpregnant adolescents and adults to inform the USPSTF. They found no direct evidence for the clinical benefits and harms of HBV screening vs no screening. Antiviral therapy for HBV infection was associated with improved intermediate outcomes and may improve clinical outcomes.
AHRQ-funded; 290201500009I.
Citation: Chou R, Blazina I, Bougatsos C .
Screening for hepatitis B virus infection in nonpregnant adolescents and adults: updated evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2020 Dec 15;324(23):2423-36. doi: 10.1001/jama.2020.19750..
Keywords: U.S. Preventive Services Task Force (USPSTF), Children/Adolescents, Hepatitis, Chronic Conditions, Screening, Evidence-Based Practice, Prevention
Chou R, Dana T, Fu R
Screening for hepatitis C virus infection in adolescents and adults: updated evidence report and systematic review for the US Preventive Services Task Force.
AHRQ-funded; 290201500009I.
Citation: Chou R, Dana T, Fu R .
Screening for hepatitis C virus infection in adolescents and adults: updated evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2020 Mar 10;323(10):970-75. doi: 10.1001/jama.2019.20788..
Keywords: U.S. Preventive Services Task Force (USPSTF), Children/Adolescents, Hepatitis, Chronic Conditions, Screening, Evidence-Based Practice, Prevention
Henderson JT, Webber EM, Bean SI
Screening for hepatitis B infection in pregnant women: updated evidence report and systematic review for the US Preventive Services Task Force.
In this research letter, the authors described their evidence update conducted to inform the USPSTF in updating its 2009 recommendation. They found that targeted resources are needed to ensure that case management is effectively implemented through health care that reaches vulnerable populations most at risk of perinatal transmission of hepatitis B virus (HBV), including women born in countries where HBV is endemic. They concluded that improving access to prenatal care, screening, and case management are among the strategies to help eliminate perinatal HBV infection in the United States.
AHRQ-funded; 290201500007I.
Citation: Henderson JT, Webber EM, Bean SI .
Screening for hepatitis B infection in pregnant women: updated evidence report and systematic review for the US Preventive Services Task Force.
AHRQ-funded; 290201500007I..
Keywords: Evidence-Based Practice, Hepatitis, Pregnancy, Prevention, Screening, U.S. Preventive Services Task Force (USPSTF), Women
Schmajuk G, Tonner C, Trupin L
Using health-system-wide data to understand hepatitis B virus prophylaxis and reactivation outcomes in patients receiving rituximab.
Hepatitis B virus (HBV) reactivation in the setting of rituximab use is a potentially fatal but preventable safety event. The rate of HBV screening and proportion of patients at risk who receive antiviral prophylaxis in patients initiating rituximab is unknown. This study found wide variations in hepatitis B screening practices among patients receiving rituximab, resulting in unnecessary risks to patients.
AHRQ-funded; HS023558; HS024412.
Citation: Schmajuk G, Tonner C, Trupin L .
Using health-system-wide data to understand hepatitis B virus prophylaxis and reactivation outcomes in patients receiving rituximab.
Medicine 2017 Mar;96(13):e6528. doi: 10.1097/md.0000000000006528.
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Keywords: Hepatitis, Electronic Health Records (EHRs), Medication, Prevention, Patient Safety
Simons BC, Spradling PR, Bruden DJ
A longitudinal hepatitis B vaccine cohort demonstrates long-lasting hepatitis B virus (HBV) cellular immunity despite loss of antibody against HBV surface antigen.
The purpose of this paper is to determine long-lasting protection resulting from hepatitis B vaccine, despite loss of antibody against hepatitis B virus (HBV) surface antigen (anti-HBs). All participants tested positive for tumor necrosis factor α, interleukin 10, or interleukin 6 production by HBV surface antigen-specific T cells. No participant had evidence of breakthrough HBV infection. The authors concluded that protection afforded by primary immunization with plasma-derived hepatitis B vaccine during childhood and adulthood lasts at least 32 years.
AHRQ-funded; HS000046.
Citation: Simons BC, Spradling PR, Bruden DJ .
A longitudinal hepatitis B vaccine cohort demonstrates long-lasting hepatitis B virus (HBV) cellular immunity despite loss of antibody against HBV surface antigen.
J Infect Dis 2016 Jul 15;214(2):273-80. doi: 10.1093/infdis/jiw142.
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Keywords: Hepatitis, Prevention, Vaccination
Mabry-Hernandez I, Lewis P
AHRQ Author: Mabry-Hernandez I
Screening for hepatitis B virus infection in nonpregnant adolescents and adults.
This paper presents a case study and quiz regarding a 35-year-old man whose parents were born in southeast Asia. Although he was born in the United States, he. does not have any vaccination records from his childhood. During an office visit, he mentions that a relative was recently diagnosed with hepatitis B virus (HBV) infection and asks whether he should be screened. Correct answers are based on the U.S. Preventive Services Task Force Recommendation Statement.
AHRQ-authored.
Citation: Mabry-Hernandez I, Lewis P .
Screening for hepatitis B virus infection in nonpregnant adolescents and adults.
Am Fam Physician 2015 Aug 15;92(4):301-2..
Keywords: U.S. Preventive Services Task Force (USPSTF), Screening, Hepatitis, Prevention