National Healthcare Quality and Disparities Report
Latest available findings on quality of and access to health care
Data
- Data Infographics
- Data Visualizations
- Data Tools
- Data Innovations
- All-Payer Claims Database
- Healthcare Cost and Utilization Project (HCUP)
- Medical Expenditure Panel Survey (MEPS)
- AHRQ Quality Indicator Tools for Data Analytics
- State Snapshots
- United States Health Information Knowledgebase (USHIK)
- Data Sources Available from AHRQ
Search All Research Studies
AHRQ Research Studies Date
Topics
- Adverse Events (1)
- (-) Brain Injury (8)
- Care Management (1)
- Children/Adolescents (1)
- Clinical Decision Support (CDS) (1)
- Critical Care (1)
- Elderly (1)
- Emergency Department (2)
- Evidence-Based Practice (1)
- Guidelines (1)
- Healthcare Cost and Utilization Project (HCUP) (1)
- Healthcare Costs (1)
- Healthcare Utilization (1)
- Imaging (1)
- Intensive Care Unit (ICU) (1)
- Medication (2)
- Neurological Disorders (3)
- Outcomes (3)
- Patient-Centered Outcomes Research (3)
- Patient Safety (1)
- Quality of Life (1)
- Racial and Ethnic Minorities (1)
- Research Methodologies (1)
- Shared Decision Making (1)
- Sleep Problems (1)
- Trauma (1)
AHRQ Research Studies
Sign up: AHRQ Research Studies Email updates
Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 8 of 8 Research Studies DisplayedWickwire EM, Schnyer DM, Germain A
Sleep, sleep disorders, and circadian health following mild traumatic brain injury in adults: review and research agenda.
A rapidly expanding scientific literature supports the frequent co-occurrence of sleep and circadian disturbances following mild traumatic brain injury (mTBI). In this paper, the authors review relevant literature and present a research agenda to 1) advance understanding of the reciprocal relationships between sleep and circadian factors and mTBI sequelae and 2) advance rapidly the development of sleep-related treatments in this population.
AHRQ-funded; HS024560.
Citation: Wickwire EM, Schnyer DM, Germain A .
Sleep, sleep disorders, and circadian health following mild traumatic brain injury in adults: review and research agenda.
J Neurotrauma 2018 Nov 15;35(22):2615-31. doi: 10.1089/neu.2017.5243..
Keywords: Sleep Problems, Brain Injury, Evidence-Based Practice
Albrecht JS, Perfetto EM, Daniel Mullins C
Safety of antidepressant classes used following traumatic brain injury among Medicare beneficiaries: a retrospective cohort study.
The objective of this study was to compare the risk of several adverse events associated with use of the three most commonly used classes of antidepressants following Traumatic Brain Injury (TBI) in older adults. One of the study’s conclusions was that compared to tricyclic antidepressants, selective serotonin reuptake inhibitor use was associated with increased risk of hemorrhagic stroke.
AHRQ-funded; HS024560
Citation: Albrecht JS, Perfetto EM, Daniel Mullins C .
Safety of antidepressant classes used following traumatic brain injury among Medicare beneficiaries: a retrospective cohort study.
Drugs Aging 2018 Aug;35(8):763-72. doi: 10.1007/s40266-018-0570-2..
Keywords: Adverse Events, Medication, Brain Injury, Elderly, Patient Safety
Sander AM, Lequerica AH, Ketchum JM
Race/ethnicity and retention in traumatic brain injury outcomes research: a traumatic brain injury model systems national database study.
The purpose of this study was to investigate the contribution of race/ethnicity to retention in traumatic brain injury (TBI) research at 1 to 2 years postinjury. The findings emphasized the importance of investigating retention rates separately for blacks and Hispanics rather than combining them or grouping either with other races or ethnicities. The results also suggested the need for implementing procedures to increase retention of Hispanics in longitudinal TBI research.
AHRQ-funded; HS022134.
Citation: Sander AM, Lequerica AH, Ketchum JM .
Race/ethnicity and retention in traumatic brain injury outcomes research: a traumatic brain injury model systems national database study.
J Head Trauma Rehabil 2018 Jul/Aug;33(4):219-27. doi: 10.1097/htr.0000000000000395..
Keywords: Brain Injury, Racial and Ethnic Minorities, Outcomes, Patient-Centered Outcomes Research, Research Methodologies
Chen C, Peng J, Sribnick EA
Trend of age-adjusted rates of pediatric traumatic brain injury in U.S. emergency departments from 2006 to 2013.
The objective of this study was to use the 2006(-)2013 Nationwide Emergency Department Sample (NEDS) database to describe trends of age-adjusted rates of pediatric traumatic brain injuries (TBI) treated in U.S. emergency departments. The investigators found that the overall age-adjusted rates of pediatric TBI-related emergency department (ED) visits increased from 2006 to 2013, which was largely caused by pediatric mild TBIs, especially unspecified injury to the head (ICD-9-CM code 959.01) and concussion.
AHRQ-funded; HS024263.
Citation: Chen C, Peng J, Sribnick EA .
Trend of age-adjusted rates of pediatric traumatic brain injury in U.S. emergency departments from 2006 to 2013.
Int J Environ Res Public Health 2018 Jun 5;15(6). doi: 10.3390/ijerph15061171..
Keywords: Brain Injury, Children/Adolescents, Emergency Department, Healthcare Cost and Utilization Project (HCUP), Trauma
Mahmoud L, Zullo AR, Thompson BB
Outcomes of protocolised analgesia and sedation in a neurocritical care unit.
Researchers conducted a retrospective cohort study of 1197 mechanically ventilated patients admitted to a 12-bed neurocritical care unit (NCCU) over four years in order to evaluate the effect of an analgesia-based sedation protocol on medication use and costs in the NCCU. The protocol resulted in increased in fentanyl use and decreased in propofol use, but their findings indicate no effect on healthcare utilization, healthcare costs, or in-hospital mortality. Based on these results, the researchers suggest that similar NCCUs should consider using population-specific protocols to manage analgesia and sedation.
AHRQ-funded; HS022998.
Citation: Mahmoud L, Zullo AR, Thompson BB .
Outcomes of protocolised analgesia and sedation in a neurocritical care unit.
Brain Inj 2018;32(7):941-47. doi: 10.1080/02699052.2018.1469167..
Keywords: Care Management, Brain Injury, Critical Care, Healthcare Costs, Intensive Care Unit (ICU), Medication, Neurological Disorders, Outcomes, Patient-Centered Outcomes Research
Bush RA, Beaumont JL, Liotta EM
Fever burden and health-related quality of life after intracerebral hemorrhage.
In this prospective observational cohort study, the investigators tested the hypothesis that increased burden of fever is independently associated with decreased health-related quality of life (HRQoL) at follow-up. The authors found that each additional day with a fever was predictive of worse HRQoL domains of Cognitive Function and Mobility after intracerebral hemorrhage up to 1 year. They suggest that HRQoL outcomes may be a sensitive and powerful way to measure the efficacy of fever control in future research.
AHRQ-funded; HS023437.
Citation: Bush RA, Beaumont JL, Liotta EM .
Fever burden and health-related quality of life after intracerebral hemorrhage.
Neurocrit Care 2018 Mar 29;29(2):189-94. doi: 10.1007/s12028-018-0523-y..
Keywords: Brain Injury, Neurological Disorders, Outcomes, Patient-Centered Outcomes Research, Quality of Life
Callahan ML, Binder LM, O'Neil ME
Sensory sensitivity in operation enduring freedom/operation Iraqi freedom veterans with and without blast exposure and mild traumatic brain injury.
To examine factors associated with noise and light sensitivity among returning Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Veterans with a self-reported history of mild traumatic brain injury (mTBI) due to blast exposure, the researchers compared the self-report of noise and light sensitivity of 42 OEF/OIF Veterans diagnosed with mTBI resulting from combat blast-exposure to that of 36 blast-exposed OEF/OIF Veterans without a history of mTBI.
AHRQ-funded; HS022981.
Citation: Callahan ML, Binder LM, O'Neil ME .
Sensory sensitivity in operation enduring freedom/operation Iraqi freedom veterans with and without blast exposure and mild traumatic brain injury.
Appl Neuropsychol Adult 2018 Mar-Apr;25(2):126-36. doi: 10.1080/23279095.2016.1261867..
Keywords: Brain Injury, Neurological Disorders
Sharp AL, Huang BZ, Tang T
Implementation of the Canadian CT Head Rule and Its association with use of computed tomography among patients with head injury.
The researchers evaluated the association of implementation of the Canadian CT Head Rule on head computed tomography (CT) imaging in community emergency departments (EDs). They found that a multicomponent implementation of the Canadian CT Head Rule was associated with a modest reduction in CT use and an increased diagnostic yield of head CTs for adult trauma encounters in community EDs.
AHRQ-funded; HS021271.
Citation: Sharp AL, Huang BZ, Tang T .
Implementation of the Canadian CT Head Rule and Its association with use of computed tomography among patients with head injury.
Ann Emerg Med 2018 Jan;71(1):54-63.e2. doi: 10.1016/j.annemergmed.2017.06.022.
.
.
Keywords: Brain Injury, Clinical Decision Support (CDS), Shared Decision Making, Emergency Department, Guidelines, Healthcare Utilization, Imaging