National Healthcare Quality and Disparities Report
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Search All Research Studies
Topics
- Adverse Events (1)
- Education: Patient and Caregiver (1)
- Healthcare-Associated Infections (HAIs) (2)
- Hospital Discharge (1)
- Hospitalization (2)
- Hospitals (1)
- Infectious Diseases (1)
- Injuries and Wounds (1)
- (-) Methicillin-Resistant Staphylococcus aureus (MRSA) (6)
- Mortality (1)
- Newborns/Infants (1)
- Patient-Centered Outcomes Research (1)
- Prevention (1)
- (-) Risk (6)
- Surgery (1)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 6 of 6 Research Studies DisplayedHuang SS, Singh R, McKinnell JA
Decolonization to reduce postdischarge infection risk among MRSA carriers.
This study compared postdischarge methicillin-resistant Staphylococcus aureus (MRSA) rates in study participant who received education alone versus decolonization and education. Decolonization was done with chlorhexidine mouthwash and showers, and nasal sprays. Decolonization with education resulted in a 30% reduction in MRSA infection versus education alone.
AHRQ-funded; HS019388.
Citation: Huang SS, Singh R, McKinnell JA .
Decolonization to reduce postdischarge infection risk among MRSA carriers.
N Engl J Med 2019 Feb 14;380(7):638-50. doi: 10.1056/NEJMoa1716771..
Keywords: Education: Patient and Caregiver, Healthcare-Associated Infections (HAIs), Hospital Discharge, Methicillin-Resistant Staphylococcus aureus (MRSA), Prevention, Risk
Muenks CE, Hogan PG, Wang JW
Diversity of Staphylococcus aureus strains colonizing various niches of the human body.
The objectives of this study were to determine whether S. aureus polyclonal colonization exists within one body niche and to determine the optimal sampling sites and culture methodology to capture the diversity of S. aureus strains in community-dwelling individuals. The researchers found S. aureus polyclonality within a single body niche and that culture methodology and sampling sites influenced the analytical sensitivity of S. aureus colonization detection and the robustness of phenotypic and genotypic strain recovery.
AHRQ-funded; HS021736; HS024269.
Citation: Muenks CE, Hogan PG, Wang JW .
Diversity of Staphylococcus aureus strains colonizing various niches of the human body.
J Infect 2016 Jun;72(6):698-705. doi: 10.1016/j.jinf.2016.03.015.
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Keywords: Infectious Diseases, Methicillin-Resistant Staphylococcus aureus (MRSA), Risk
Baker AW, Dicks KV, Durkin MJ
Epidemiology of surgical site infection in a community hospital network.
The researchers described the epidemiology of complex surgical site infection (SSI) following commonly performed surgical procedures in community hospitals and to characterize trends of SSI prevalence rates over time for MRSA and other common pathogens. They found that the prevalence of MRSA SSI decreased from 2008 to 2012. This decrease in MRSA SSI prevalence led to an overall decrease in SSI prevalence.
AHRQ-funded; HS023866.
Citation: Baker AW, Dicks KV, Durkin MJ .
Epidemiology of surgical site infection in a community hospital network.
Infect Control Hosp Epidemiol 2016 May;37(5):519-26. doi: 10.1017/ice.2016.13.
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Keywords: Surgery, Healthcare-Associated Infections (HAIs), Methicillin-Resistant Staphylococcus aureus (MRSA), Injuries and Wounds, Adverse Events, Risk, Hospitals
Ericson JE, Popoola VO, Smith PB
Burden of invasive staphylococcus aureus infections in hospitalized infants.
This study compared demographics and mortality of inf ants with invasive methicillin-resistant S aureus (MRSA) and methicillin-susceptible S aureus (MSSA), to determine the annual proportion of S aureus infections that were MRSA. It found that infant mortality after invasive MRSA and MSSA infections was similar, but MSSA caused more infections and more deaths in infants than MRSA.
AHRQ-funded; HS022872.
Citation: Ericson JE, Popoola VO, Smith PB .
Burden of invasive staphylococcus aureus infections in hospitalized infants.
JAMA Pediatr 2015 Dec;169(12):1105-11. doi: 10.1001/jamapediatrics.2015.2380..
Keywords: Newborns/Infants, Methicillin-Resistant Staphylococcus aureus (MRSA), Mortality, Hospitalization, Risk
Teshome BF, Lee GC, Reveles KR
Application of a methicillin-resistant Staphylococcus aureus risk score for community-onset pneumonia patients and outcomes with initial treatment.
The study objective was to assess the effect of initial MRSA therapy on mortality in community–onset (CO) pneumonia patients that a new MRSA prediction score had classified into low, medium, and high-risk groups based on objective criteria available at baseline. The study demonstrated improved survival with initial MRSA therapy in the 2 percent of CO-pneumonia patients classified as high-risk.
AHRQ-funded; HS022418.
Citation: Teshome BF, Lee GC, Reveles KR .
Application of a methicillin-resistant Staphylococcus aureus risk score for community-onset pneumonia patients and outcomes with initial treatment.
BMC Infect Dis 2015 Sep 18;15:380. doi: 10.1186/s12879-015-1119-1..
Keywords: Methicillin-Resistant Staphylococcus aureus (MRSA), Risk, Patient-Centered Outcomes Research, Hospitalization
Wardyn SE, Forshey BM, Farina SA
Swine farming is a risk factor for infection with and high prevalence of carriage of multidrug-resistant Staphylococcus aureus.
The researchers conducted a large-scale prospective study of 1,342 Iowans, including individuals with livestock contact and a community-based comparison group. They found that current swine workers are 6 times more likely to carry multidrug-resistant S. aureus than those without current swine exposure. Also, they observed active infections caused by livestock-associated S. aureus.
AHRQ-funded; HS019966.
Citation: Wardyn SE, Forshey BM, Farina SA .
Swine farming is a risk factor for infection with and high prevalence of carriage of multidrug-resistant Staphylococcus aureus.
Clin Infect Dis 2015 Jul 1;61(1):59-66. doi: 10.1093/cid/civ234..
Keywords: Risk, Methicillin-Resistant Staphylococcus aureus (MRSA)