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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 8 of 8 Research Studies DisplayedBaker JM, Tate JE, Steiner CA
AHRQ Author: Steiner CA
Longer-term direct and indirect effects of infant rotavirus vaccination across all ages in the US; 2000 - 2013: analysis of a large hospital discharge dataset.
Rotavirus disease dramatically declined among children under 5 years of age since the rotavirus vaccine was introduced in 2006. In this study, data from the Healthcare Cost and Utilization Project State Inpatient Database were used to conduct a time-series analysis of monthly hospital discharges across age groups for acute gastroenteritis and rotavirus from 2000-2013, in order to elucidate population level impacts.
AHRQ-authored.
Citation: Baker JM, Tate JE, Steiner CA .
Longer-term direct and indirect effects of infant rotavirus vaccination across all ages in the US; 2000 - 2013: analysis of a large hospital discharge dataset.
Clin Infect Dis 2019 Mar 15;68(6):976-83. doi: 10.1093/cid/ciy580..
Keywords: Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Infectious Diseases, Vaccination
Shah MP, Lopman BA, Tate JE
AHRQ Author: Steiner CA
Use of Internet search data to monitor rotavirus vaccine impact in the United States, United Kingdom, and Mexico.
In this study, researchers aimed to study the correlation between internet query searches (IQS) for "rotavirus" and rotavirus disease activity in the United States, United Kingdom, and Mexico before and after introduction of rotavirus vaccine. They found positive correlation between the rotavirus IQS and laboratory reports in the United States and United Kingdom and between the rotavirus IQS and acute gastroenteritis hospitalizations in the United States and Mexico for all correlations.
AHRQ-authored.
Citation: Shah MP, Lopman BA, Tate JE .
Use of Internet search data to monitor rotavirus vaccine impact in the United States, United Kingdom, and Mexico.
J Pediatric Infect Dis Soc 2018 Feb 19;7(1):56-63. doi: 10.1093/jpids/pix004.
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Keywords: Healthcare Cost and Utilization Project (HCUP), Vaccination, Web-Based
Pringle KD, Burke RM, Steiner CA
AHRQ Author: Steiner CA
Trends in rate of seizure-associated hospitalizations among children <5 years old before and after rotavirus vaccine introduction in the United Sates, 2000-2013.
Since rotavirus vaccine introduction, hospitalizations for treatment of acute gastroenteritis have decreased. Researchers assessed whether there has been an associated decrease in seizure-associated hospitalizations. Their analysis provides evidence for a decrease in seizure hospitalizations following rotavirus vaccine introduction in the United States, with the greatest impact in age groups with a high rotavirus-associated disease burden and during rotavirus infection season.
AHRQ-authored.
Citation: Pringle KD, Burke RM, Steiner CA .
Trends in rate of seizure-associated hospitalizations among children <5 years old before and after rotavirus vaccine introduction in the United Sates, 2000-2013.
J Infect Dis 2018 Jan 30;217(4):581-88. doi: 10.1093/infdis/jix589.
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Keywords: Adverse Drug Events (ADE), Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Vaccination
Leshem E, Tate JE, Steiner CA
AHRQ Author: Steiner. CA
National estimates of reductions in acute gastroenteritis-related hospitalizations and associated costs in US children after implementation of rotavirus vaccines.
The study compared acute gastroenteritis (AGE)-related hospitalization rates among children <5 years of age during the pre-rotavirus vaccine (2000-2006) and post-rotavirus vaccine (2008-2013) periods to estimate national reductions in AGE-related hospitalizations and associated costs.
AHRQ-authored
Citation: Leshem E, Tate JE, Steiner CA .
National estimates of reductions in acute gastroenteritis-related hospitalizations and associated costs in US children after implementation of rotavirus vaccines.
J Pediatric Infect Dis Soc 2017 Aug 17;7(3):257-60. doi: 10.1093/jpids/pix057..
Keywords: Children/Adolescents, Healthcare Costs, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Vaccination
Wiese AD, Griffin MR, Zhu Y
Changes in empyema among U.S. children in the pneumococcal conjugate vaccine era.
The authors assessed changes in the incidence of empyema hospitalizations among U.S. children after the PCV13 vaccine introduction. They found that although empyema hospitalization rates among U.S. children peaked after the PCV7 vaccine introduction, rates decreased substantially following the introduction of PCV13.
AHRQ-funded; HS022342.
Citation: Wiese AD, Griffin MR, Zhu Y .
Changes in empyema among U.S. children in the pneumococcal conjugate vaccine era.
Vaccine 2016 Dec 7;34(50):6243-49. doi: 10.1016/j.vaccine.2016.10.062.
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Keywords: Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Vaccination
Tate JE, Yen C, Steiner CA
AHRQ Author: Steiner CA
Intussusception rates before and after the introduction of rotavirus vaccine.
The researchers examined trends in intussusception hospitalizations before (2000-2005) and after (2007-2013) rotavirus vaccine introduction to assess whether this observed temporal risk translates into more hospitalized cases at the population level. They concluded that, given the magnitude of declines in rotavirus disease compared with this small increase in intussusception, the benefits of rotavirus vaccination outweigh the increase risk of intussusception.
AHRQ-authored.
Citation: Tate JE, Yen C, Steiner CA .
Intussusception rates before and after the introduction of rotavirus vaccine.
Pediatrics 2016 Sep;138(3). doi: 10.1542/peds.2016-1082.
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Keywords: Healthcare Cost and Utilization Project (HCUP), Vaccination, Adverse Drug Events (ADE), Hospitalization
Shah MP, Tate JE, Steiner CA
AHRQ Author: Steiner CA
Decline in emergency department visits for acute gastroenteritis among children in 10 US states after implementation of rotavirus vaccination, 2003-2013.
The researchers compared the rates of gastroenteritis- and rotavirus-coded ED visits among children <5 years of age in pre-rotavirus vaccine (2003 to 2006) with those in postvaccine (2008-2013) years; 2007 was excluded as a transition year They concluded that. ED visits for gastroenteritis in US children have declined since the introduction of rotavirus vaccine.
AHRQ-authored.
Citation: Shah MP, Tate JE, Steiner CA .
Decline in emergency department visits for acute gastroenteritis among children in 10 US states after implementation of rotavirus vaccination, 2003-2013.
Pediatr Infect Dis J 2016 Jul;35(7):782-6. doi: 10.1097/inf.0000000000001175.
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Keywords: Healthcare Cost and Utilization Project (HCUP), Children/Adolescents, Vaccination, Emergency Medical Services (EMS), Digestive Disease and Health
Leshem E, Tate JE, Steiner CA
AHRQ Author: Steiner CA
Acute gastroenteritis hospitalizations among US children following implementation of the rotavirus vaccine.
Because laboratory testing and coding for rotavirus are not routinely performed for patients with diarrhea, the researchers examined both all-cause acute gastroenteritis and rotavirus-coded hospitalizations among children younger than 5 years from 2000 through 2012. They found that, in 2012, when vaccine coverage was highest, the greatest reductions were observed for all-cause acute gastroenteritis (55 percent) and rotavirus-coded (94 percent) hospitalizations.
AHRQ-authored.
Citation: Leshem E, Tate JE, Steiner CA .
Acute gastroenteritis hospitalizations among US children following implementation of the rotavirus vaccine.
JAMA 2015 Jun 9;313(22):2282-4. doi: 10.1001/jama.2015.5571..
Keywords: Healthcare Cost and Utilization Project (HCUP), Hospitalization, Vaccination, Children/Adolescents, Adverse Events