National Healthcare Quality and Disparities Report
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- (-) Women (32)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 25 of 32 Research Studies DisplayedGartlehner G, Patel SV, Feltner C
Hormone therapy for the primary prevention of chronic conditions in postmenopausal women: evidence report and systematic review for the US Preventive Services Task Force.
This review updated evidence for the US Preventive Services Task Force on the benefits and harms of hormone therapy in reducing risks for chronic conditions. It concluded that hormone therapy for the primary prevention of chronic conditions in menopausal women is associated with some beneficial effects but also with a substantial increase of risks for harms. The available evidence regarding benefits and harms of early initiation of hormone therapy is inconclusive.
AHRQ-funded; 290201200015I.
Citation: Gartlehner G, Patel SV, Feltner C .
Hormone therapy for the primary prevention of chronic conditions in postmenopausal women: evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2017 Dec 12;318(22):2234-49. doi: 10.1001/jama.2017.16952.
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Keywords: Chronic Conditions, Evidence-Based Practice, Guidelines, Prevention, U.S. Preventive Services Task Force (USPSTF), Women
Childers CP, Childers KK, Maggard-Gibbons M
National estimates of genetic testing in women with a history of breast or ovarian cancer.
In the United States, 3.8 million women have a history of breast (BC) or ovarian cancer (OC). Up to 15 percent of cases are attributable to heritable mutations, which, if identified, provide critical knowledge for treatment and preventive care. This study found that fewer than one in five individuals with a history of BC or OC meeting select National Cancer Comprehensive Network criteria have undergone genetic testing.
AHRQ-funded; HS025079.
Citation: Childers CP, Childers KK, Maggard-Gibbons M .
National estimates of genetic testing in women with a history of breast or ovarian cancer.
J Clin Oncol 2017 Dec 1;35(34):3800-06. doi: 10.1200/jco.2017.73.6314.
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Keywords: Cancer, Cancer: Breast Cancer, Cancer: Ovarian Cancer, Family Health and History, Genetics, Quality of Care, Screening, Women
Borah BJ, Yao X, Laughlin-Tommaso SK
Comparative effectiveness of uterine leiomyoma procedures using a large insurance claims database.
The objective of this retrospective analysis of administrative claims from a large U.S. commercial insurance database, was to compare risk of reintervention, long-term clinical outcomes, and health care utilization among women who have bulk symptoms from leiomyoma and who underwent the following procedures: hysterectomy, myomectomy, uterine artery embolization, and magnetic resonance-guided, focused ultrasound surgery.
AHRQ-funded; HS023418.
Citation: Borah BJ, Yao X, Laughlin-Tommaso SK .
Comparative effectiveness of uterine leiomyoma procedures using a large insurance claims database.
Obstet Gynecol 2017 Nov;130(5):1047-56. doi: 10.1097/AOG.0000000000002331..
Keywords: Cancer, Comparative Effectiveness, Health Insurance, Outcomes, Patient-Centered Outcomes Research, Surgery, Women
Baiocchi M, Omondi B, Langat N
A behavior-based intervention that prevents sexual assault: the results of a matched-pairs, cluster-randomized study in Nairobi, Kenya.
This study was a cluster-randomized, matched-pairs, parallel trial of a behavior-based sexual assault prevention intervention in the informal settlements in Nairobi, Kenya. The study intervention combined parallel training for young adolescent girls and boys in school settings and showed significant reduction in the rate of sexual assault among girls in this population.
AHRQ-funded; HS022192.
Citation: Baiocchi M, Omondi B, Langat N .
A behavior-based intervention that prevents sexual assault: the results of a matched-pairs, cluster-randomized study in Nairobi, Kenya.
Prev Sci 2017 Oct;18(7):818-27. doi: 10.1007/s11121-016-0701-0..
Keywords: Children/Adolescents, Education, Prevention, Women
Rauscher GH, Dabbous F, Dolecek TA
Absence of an anticipated racial disparity in interval breast cancer within a large health care organization.
The researchers sought to estimate the extent of an anticipated racial disparity in interval breast cancer (IBC) within a single, large health care organization. Contrary to expectation, in patient-adjusted models, there was no IBC racial disparity. The sorting of patients by race across facilities appears to have mitigated an otherwise anticipated disparity in IBC.
AHRQ-funded; HS018366.
Citation: Rauscher GH, Dabbous F, Dolecek TA .
Absence of an anticipated racial disparity in interval breast cancer within a large health care organization.
Ann Epidemiol 2017 Oct;27(10):654-58. doi: 10.1016/j.annepidem.2017.09.002.
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Keywords: Cancer: Breast Cancer, Cancer, Disparities, Racial and Ethnic Minorities, Women, Screening, Screening, Imaging
Ehrlich SF, Hedderson MM, Brown SD
Moderate intensity sports and exercise is associated with glycaemic control in women with gestational diabetes.
The aim of the study was to assess the association of regular, unsupervised sports and exercise during pregnancy, by intensity level, with glycaemic control in women with gestational diabetes (GDM). The study concluded that higher volumes of moderate intensity sports and exercise, reported shortly after GDM diagnosis, were significantly associated with increased odds of achieving glycaemic control.
AHRQ-funded; HS019367.
Citation: Ehrlich SF, Hedderson MM, Brown SD .
Moderate intensity sports and exercise is associated with glycaemic control in women with gestational diabetes.
Diabetes Metab 2017 Oct;43(5):416-23. doi: 10.1016/j.diabet.2017.01.006..
Keywords: Diabetes, Lifestyle Changes, Outcomes, Patient-Centered Outcomes Research, Pregnancy, Women
Offorjebe OA, Wynn A, Moshashane N
Partner notification and treatment for sexually transmitted infections among pregnant women in Gaborone, Botswana.
This paper describes a prospective cohort study which was conducted among 300 pregnant women presenting to the antenatal clinic at Princess Marina Hospital in Gaborone, Botswana who enrolled in an STI screening study. The authors specifically examine partner notification and treatment. They conclude that their findings suggest that pregnant women are willing to utilize patient-based partner notification, but actual partner treatment might be lower than intended.
AHRQ-funded; HS000046.
Citation: Offorjebe OA, Wynn A, Moshashane N .
Partner notification and treatment for sexually transmitted infections among pregnant women in Gaborone, Botswana.
Int J STD AIDS 2017 Oct;28(12):1184-89. doi: 10.1177/0956462417692455..
Keywords: Infectious Diseases, Pregnancy, Screening, Women
Ross WT, Meister MR, Shepherd JP
Utilization of apical vaginal support procedures at time of inpatient hysterectomy performed for benign conditions: a national estimate.
The researchers sought to estimate trends and factors associated with use of apical support procedures at time of inpatient hysterectomy for benign indications in a large national database. Their study demonstrated that apical support procedures are not routinely performed at time of inpatient hysterectomy regardless of presence of prolapse diagnosis.
AHRQ-funded; HS019455.
Citation: Ross WT, Meister MR, Shepherd JP .
Utilization of apical vaginal support procedures at time of inpatient hysterectomy performed for benign conditions: a national estimate.
Am J Obstet Gynecol 2017 Oct;217(4):436.e1-36.e8. doi: 10.1016/j.ajog.2017.07.010.
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Keywords: Healthcare Utilization, Practice Patterns, Surgery, Women
Cook SC, Gunter KE, Lopez FY
Establishing effective health care partnerships with sexual and gender minority patients: recommendations for obstetrician gynecologists.
Sexual and gender minority patients have historically experienced high rates of inappropriate and low-quality care, disrespect, and discrimination in health care settings, as well as significant health disparities. This article documented multiple suggestions and resources that health care teams can use to improve the health and health care of their sexual and gender minority patients.
AHRQ-funded; HS023050.
Citation: Cook SC, Gunter KE, Lopez FY .
Establishing effective health care partnerships with sexual and gender minority patients: recommendations for obstetrician gynecologists.
Semin Reprod Med 2017 Sep;35(5):397-407. doi: 10.1055/s-0037-1604464..
Keywords: Racial and Ethnic Minorities, Patient-Centered Healthcare, Clinician-Patient Communication, Women
Calderwood MS, Huang SS, Keller V
Variable case detection and many unreported cases of surgical-site infection following colon surgery and abdominal hysterectomy in a statewide validation.
This study assesses hospital surgical-site infection (SSI) identification and reporting following colon surgery and abdominal hysterectomy via a statewide external validation. The authors concluded that claims-based surveillance is a standardized approach that hospitals can use to augment traditional surveillance methods and health departments can use for external validation.
AHRQ-funded; HS021424.
Citation: Calderwood MS, Huang SS, Keller V .
Variable case detection and many unreported cases of surgical-site infection following colon surgery and abdominal hysterectomy in a statewide validation.
Infect Control Hosp Epidemiol 2017 Sep;38(9):1091-97. doi: 10.1017/ice.2017.134..
Keywords: Healthcare-Associated Infections (HAIs), Surgery, Injuries and Wounds, Patient Safety, Women, Adverse Events, Diagnostic Safety and Quality, Hospitals
Fan T, Amobi A
AHRQ Author: Fan T
Screening for gynecologic conditions with pelvic examination.
A 37-year-old woman presents to your office for her annual wellness visit. She is not due for a Papanicolaou (Pap) smear this year. She is not pregnant, reports no problems, and has no risk factors for sexually transmitted infections. She asks if she should have a pelvic examination today. The case study asks a series of three questions based on the USPSTF recommendation statement. Answers are provided.
AHRQ-authored.
Citation: Fan T, Amobi A .
Screening for gynecologic conditions with pelvic examination.
Am Fam Physician 2017 Aug 15;96(4):253-54.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Women, Case Study, Decision Making, Screening
Metz TD, Gonzalez C, Allshouse AA
Influence of patient-level factors on mode of delivery among operative vaginal delivery candidates in modern practice.
This study aimed to evaluate which patient-level factors influence mode of delivery among candidates for operative vaginal delivery. Odds of forceps versus vacuum were higher with induction, nulliparity, epidural, maternal indication, older maternal age, and longer second stage. Odds of cesarean versus operative vaginal delivery were higher with maternal indication, a perinatologist, longer second stage, older gestational age and longer labor.
AHRQ-funded; HS022143.
Citation: Metz TD, Gonzalez C, Allshouse AA .
Influence of patient-level factors on mode of delivery among operative vaginal delivery candidates in modern practice.
Am J Perinatol 2017 Aug;34(10):974-81. doi: 10.1055/s-0037-1601441.
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Keywords: Adverse Events, Healthcare Delivery, Labor and Delivery, Pregnancy, Women
Thomas HN, Hamm M, Hess R
Patient-centered outcomes and treatment preferences regarding sexual problems: a qualitative study among midlife women.
This study sought a better understanding of the sexual function outcomes that were most important to sexually active women 45 to 60 years old and the types of treatments they would prefer from individual interviews and focus groups. It found that many midlife women in the sample expressed a preference for behavioral approaches over pharmaceutical approaches for the treatment of sexual dysfunction.
AHRQ-funded; HS022989.
Citation: Thomas HN, Hamm M, Hess R .
Patient-centered outcomes and treatment preferences regarding sexual problems: a qualitative study among midlife women.
J Sex Med 2017 Aug;14(8):1011-17. doi: 10.1016/j.jsxm.2017.05.014..
Keywords: Sexual Health, Women, Patient-Centered Outcomes Research, Quality of Life
Masinter LM, Dina B, Kjerulff K
Short interpregnancy intervals: results from the first baby study.
Short interpregnancy interval (SIPI), defined as 18 months or fewer between delivery and subsequent conception, has become an independent marker of maternal and child health. The authors of this study performed a secondary analysis of 18 months of data from The First Baby Study, a prospective cohort of women followed from pregnancy through 3 years after their first birth.
AHRQ-funded; HS000078.
Citation: Masinter LM, Dina B, Kjerulff K .
Short interpregnancy intervals: results from the first baby study.
Womens Health Issues 2017 Jul - Aug;27(4):426-33. doi: 10.1016/j.whi.2017.02.011..
Keywords: Pregnancy, Labor and Delivery, Women
Epstein DA, Lee NB, Kang JH
Examining menstrual tracking to inform the design of personal informatics tools.
The researchers considered why and how women track their menstrual cycles, examining their experiences to extend the field's understanding of personal informatics tools. They found that women track their menstrual cycle for varied reasons that include remembering and predicting their period. Participants described six methods of tracking their menstrual cycles, including use of technology, awareness of their premenstrual physiological states, and simply remembering.
AHRQ-funded; HS023654.
Citation: Epstein DA, Lee NB, Kang JH .
Examining menstrual tracking to inform the design of personal informatics tools.
Proc SIGCHI Conf Hum Factor Comput Syst 2017 May 02;2017:6876-88. doi: 10.1145/3025453.3025635.
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Keywords: Health Information Technology (HIT), Patient Self-Management, Women
Attanasio LB, Kozhimannil KB, Srinivas SK
Concordance between women's self-reported reasons for cesarean delivery and hospital discharge records.
Researchers compared women's self-reported reasons for cesarean with their hospital discharge records and examined correlates of variability in agreement between sources. Ninety-one percent of women reported a reason for their cesarean that was present in the discharge data. Positive predictive value (PPV), the probability that women's self-reported reasons for cesarean varied by reason for cesarean, with high PPV for dystocia, macrosomia, and cephalopelvic disproportion (91.1 percent), and lower PPV for malposition (81.7 percent).
AHRQ-funded; HS024215.
Citation: Attanasio LB, Kozhimannil KB, Srinivas SK .
Concordance between women's self-reported reasons for cesarean delivery and hospital discharge records.
Womens Health Issues 2017 May - Jun;27(3):329-35. doi: 10.1016/j.whi.2016.12.006.
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Keywords: Hospital Discharge, Labor and Delivery, Pregnancy, Women
Brousseau EC, Danilack V, Cai F
Emergency department visits for postpartum hypertension.
The purpose of this study was to describe the characteristics of women diagnosed with postpartum hypertension in an emergency department (ED) to better inform postpartum care. The investigators compared women with an ED diagnosis of hypertension to women with all other ED diagnoses and concluded that postpartum surveillance may not prevent readmission for hypertension.
AHRQ-funded; HS025013.
Citation: Brousseau EC, Danilack V, Cai F .
Emergency department visits for postpartum hypertension.
Hypertens Pregnancy 2017 May;36(2):212-16. doi: 10.1080/10641955.2017.1299171..
Keywords: Emergency Department, Blood Pressure, Maternal Care, Women
Kozhimannil KB, Graves AJ, Jarlenski M
Non-medical opioid use and sources of opioids among pregnant and non-pregnant reproductive-aged women.
This study characterized non-medical use (NMU) of prescription opioids among reproductive-age U.S. women, with a focus on pregnancy status. Nearly 1 percent of pregnant women and 2.3 percent of non-pregnant reproductive-age women reported opioid NMU in the past 30 days. Forty-six percent of pregnant women identified a doctor as their source compared with 27.6 percent of non-pregnant women reporting NMU.
AHRQ-funded; HS000029.
Citation: Kozhimannil KB, Graves AJ, Jarlenski M .
Non-medical opioid use and sources of opioids among pregnant and non-pregnant reproductive-aged women.
Drug Alcohol Depend 2017 May 1;174:201-08. doi: 10.1016/j.drugalcdep.2017.01.003.
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Keywords: Medication, Opioids, Pregnancy, Substance Abuse, Women
Darney BG, Biel FM, Quigley BP
Primary cesarean delivery patterns among women with physical, sensory, or intellectual disabilities.
This study sought to determine whether physical, sensory, or intellectual and developmental disabilities are independently associated with primary cesarean delivery. It found that women across disability subgroups have higher odds of cesarean delivery, and there is heterogeneity by disability type.
AHRQ-funded; HS022981.
Citation: Darney BG, Biel FM, Quigley BP .
Primary cesarean delivery patterns among women with physical, sensory, or intellectual disabilities.
Womens Health Issues 2017 May - Jun;27(3):336-44. doi: 10.1016/j.whi.2016.12.007.
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Keywords: Disabilities, Labor and Delivery, Patient-Centered Outcomes Research, Pregnancy, Women
Henderson JT, Thompson JH, Burda BU
Preeclampsia screening: evidence report and systematic review for the US Preventive Services Task Force.
The researchers systematically reviewed the benefits and harms of preeclampsia screening and risk assessment for the US Preventive Services Task Force. Their review of 21 studies concluded that evidence to estimate benefits and harms of preeclampsia screening and the test performance of different screening approaches over the course of pregnancy was limited. Externally validated risk prediction models had limited applicability.
AHRQ-funded; 290201200151I.
Citation: Henderson JT, Thompson JH, Burda BU .
Preeclampsia screening: evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2017 Apr 25;317(16):1668-83. doi: 10.1001/jama.2016.18315.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Pregnancy, Blood Pressure, Screening, Evidence-Based Practice, Guidelines, Women, Prevention
Guirguis-Blake JM, Henderson JT, Perdue LA
Periodic screening pelvic examination: evidence report and systematic review for the US Preventive Services Task Force.
The researchers systematically reviewed literature on health benefits, accuracy, and harms of the screening pelvic examination for gynecologic conditions for the US Preventive Services Task Force (USPSTF). : No direct evidence was identified for overall benefits and harms of the pelvic examination as a 1-time or periodic screening test. Limited evidence was identified regarding the diagnostic accuracy and harms of routine screening pelvic examinations in asymptomatic primary care populations.
AHRQ-funded.
Citation: Guirguis-Blake JM, Henderson JT, Perdue LA .
Periodic screening pelvic examination: evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2017 Mar 7;317(9):954-66. doi: 10.1001/jama.2016.12819.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Screening, Evidence-Based Practice, Women, Prevention
Dabbous FM, Dolecek TA, Berbaum ML
Impact of a false-positive screening mammogram on subsequent screening behavior and stage at breast cancer diagnosis.
Researchers sought to examine the impact of a false positive (FP) screening mammogram on the subsequent screening mammography behavior. They found that experiencing a FP mammogram increases the risk of late stage at diagnosis compared with prior true negative (TN) mammogram Also, women with a FP mammogram were more likely to delay their subsequent screening compared with women with a TN mammogram.
AHRQ-funded; HS018366.
Citation: Dabbous FM, Dolecek TA, Berbaum ML .
Impact of a false-positive screening mammogram on subsequent screening behavior and stage at breast cancer diagnosis.
Cancer Epidemiol Biomarkers Prev 2017 Mar;26(3):397-403. doi: 10.1158/1055-9965.epi-16-0524.
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Keywords: Cancer: Breast Cancer, Cancer, Imaging, Screening, Diagnostic Safety and Quality, Women, Prevention
Harowicz MR, Robinson TJ, Dinan MA
Algorithms for prediction of the Oncotype DX recurrence score using clinicopathologic data: a review and comparison using an independent dataset.
This study analyzed 305 patients with invasive breast cancer who had Oncotype DX recurrence scores (ODX RS) available. Five equations were selected that provide a surrogate measure of ODX by Klein (Magee equations 1-3), Gage et al., and Tang et al. Although commonly available surrogates for ODX appear to predict high-risk ODX RS, the study was unable to reliably rule out the presence of patients with intermediate-risk disease by ODX.
AHRQ-funded; HS022189.
Citation: Harowicz MR, Robinson TJ, Dinan MA .
Algorithms for prediction of the Oncotype DX recurrence score using clinicopathologic data: a review and comparison using an independent dataset.
Breast Cancer Res Treat 2017 Feb;162(1):1-10. doi: 10.1007/s10549-016-4093-4.
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Keywords: Cancer, Cancer: Breast Cancer, Genetics, Women
Lu Y, Zhou S, Dreyer RP
Sex differences in lipid profiles and treatment utilization among young adults with acute myocardial infarction: results from the VIRGO study.
This study characterized sex differences in lipid profiles and treatment utilization among young adults with acute myocardial infarction (AMI). Young women with AMI had slightly favorable lipid and lipoprotein profiles compared with men, suggesting that difference in lipid and lipoprotein may not be a major contributor to sex differences in outcomes after AMI.
AHRQ-funded; HS023000.
Citation: Lu Y, Zhou S, Dreyer RP .
Sex differences in lipid profiles and treatment utilization among young adults with acute myocardial infarction: results from the VIRGO study.
Am Heart J 2017 Jan;183:74-84. doi: 10.1016/j.ahj.2016.09.012.
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Keywords: Sex Factors, Heart Disease and Health, Healthcare Utilization, Women, Patient-Centered Outcomes Research
Taylor BD, Zheng X, Darville T
Whole-exome sequencing to identify novel biological pathways associated with infertility after pelvic inflammatory disease.
The researchers used whole-exome sequencing to identify biological pathways that may be associated with STI-related infertility. Pathway analysis revealed that focus genes were enriched in canonical pathways including, IL-1 signaling, P2Y purinergic receptor signaling, and bone morphogenic protein signaling. Targeted sequencing of biological pathways identified in this study may provide insight into STI-related infertility.
AHRQ-funded; HS008358.
Citation: Taylor BD, Zheng X, Darville T .
Whole-exome sequencing to identify novel biological pathways associated with infertility after pelvic inflammatory disease.
Sex Transm Dis 2017 Jan;44(1):35-41. doi: 10.1097/olq.0000000000000533.
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Keywords: Genetics, Sexual Health, Women