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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 3 of 3 Research Studies DisplayedKaplan J, Somohano VC, Zaccari B
Randomized controlled trials of mind-body interventions for posttraumatic stress disorder: a systematic review.
This systematic review examined strength of evidence for use of mind-body interventions (MBIs), including mindfulness-based interventions (MiBIs), meditation- and mantra-based interventions (MMIs), and movement-based interventions (MoBIs) for treatment of post-traumatic stress disorder (PTSD). The authors used the AHRQ-funded evidence tables for the PTSD-Repository to identify relevant studies and assess the risk of bias. The search was conducted between June 2018 and June 2022 using a number of relevant databases. They found 26 randomized controlled trials that met their inclusion criteria. Strength of evidence was rated as low for MiBIs and MMIs, largely due to contradicting results, inconsistent use of active versus passive comparators, and high risk of bias. It was rated as moderate for MoBIs due to individual studies consistently favoring the intervention and a relatively large number of studies and participants. Only two of the included studies had objective outcome measures.
AHRQ-funded; HS026370.
Citation: Kaplan J, Somohano VC, Zaccari B .
Randomized controlled trials of mind-body interventions for posttraumatic stress disorder: a systematic review.
Front Psychol 2024 Jan 24; 14:1219296. doi: 10.3389/fpsyg.2023.1219296.
Keywords: Complementary and Alternative Medicine, Behavioral Health
Gartlehner G, Gaynes BN, Amick HR
Comparative benefits and harms of antidepressant, psychological, complementary, and exercise treatments for major depression: An evidence report for a clinical practice guideline from the American College of Physicians.
This evidence report compared the benefits and harms of second-generation antidepressants and psychological, complementary and alternative medicine (CAM), and exercise treatments as first- and second-step interventions for adults with acute major depressive disorder (MDD). It concluded tht, given their similar efficacy, cognitive behavioral therapy and antidepressants are both viable choices for initial treatment of MDD.
AHRQ-funded.
Citation: Gartlehner G, Gaynes BN, Amick HR .
Comparative benefits and harms of antidepressant, psychological, complementary, and exercise treatments for major depression: An evidence report for a clinical practice guideline from the American College of Physicians.
Ann Intern Med 2016 Mar 1;164(5):331-41. doi: 10.7326/m15-1813.
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Keywords: Medication, Comparative Effectiveness, Complementary and Alternative Medicine, Depression, Behavioral Health
Goyal M, Singh S, Sibinga EM
Meditation programs for psychological stress and well-being: a systematic review and meta-analysis.
Many people meditate to reduce psychological stress and stress-related health problems. To counsel people appropriately, clinicians need to know what the evidence says about the health benefits of meditation. The objective of this study was to determine the efficacy of meditation programs in improving stress-related outcomes (anxiety, depression, stress/distress, positive mood, mental health-related quality of life, attention, substance use, eating habits, sleep, pain, and weight) in diverse adult clinical populations.
AHRQ-funded; 290200710061.
Citation: Goyal M, Singh S, Sibinga EM .
Meditation programs for psychological stress and well-being: a systematic review and meta-analysis.
JAMA Intern Med 2014 Mar;174(3):357-68. doi: 10.1001/jamainternmed.2013.13018..
Keywords: Behavioral Health, Complementary and Alternative Medicine, Evidence-Based Practice