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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 4 of 4 Research Studies DisplayedStillman AE, Gatsonis C, Lima JA
Rationale and design of the Randomized Evaluation of patients with Stable angina Comparing Utilization of noninvasive Examinations (RESCUE) trial.
This article describes the RESCUE trial, which is based on the hypothesis that coronary computed tomography angiography as a diagnostic tool is associated with no increase in cardiac risk, decreased cost, and reduced radiation exposure compared with single photon emission computed tomography myocardial perfusion imaging.
AHRQ-funded; HS019403.
Citation: Stillman AE, Gatsonis C, Lima JA .
Rationale and design of the Randomized Evaluation of patients with Stable angina Comparing Utilization of noninvasive Examinations (RESCUE) trial.
Am Heart J 2016 Sep;179:19-28. doi: 10.1016/j.ahj.2016.06.003.
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Keywords: Comparative Effectiveness, Imaging, Cardiovascular Conditions
Ladapo JA, Blecker S, O'Donnell M
Appropriate use of cardiac stress testing with imaging: a systematic review and meta-analysis.
The authors systematically reviewed studies of appropriate use criteria (AUC), evaluated trends over time, and characterized leading indications for inappropriate testing. They found that rates of appropriate use tend to be lower for stress echocardiography compared to myocardial perfusion imaging, and updated AUC reduced unclassified stress echocardiograms. They concluded that there is no conclusive evidence that AUC improved appropriate use over time.
AHRQ-funded; HS023683.
Citation: Ladapo JA, Blecker S, O'Donnell M .
Appropriate use of cardiac stress testing with imaging: a systematic review and meta-analysis.
PLoS One 2016 Aug 18;11(8):e0161153. doi: 10.1371/journal.pone.0161153.
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Keywords: Cardiovascular Conditions, Decision Making, Imaging, Guidelines
Ladapo JA, Blecker S, Douglas PS
Appropriateness of cardiac stress test use among primary care physicians and cardiologists in the United States.
In this study, the researchers used nationally-representative data to examine differences in appropriate use of cardiac stress testing between cardiologists and primary care physicians (PCPs) in the US. Using permissive criteria to determine appropriateness, they found that primary care physicians are more likely to order or perform a rarely appropriate cardiac stress test than cardiologists.
AHRQ-funded; HS023683.
Citation: Ladapo JA, Blecker S, Douglas PS .
Appropriateness of cardiac stress test use among primary care physicians and cardiologists in the United States.
Int J Cardiol 2016 Jan 15;203:584-6. doi: 10.1016/j.ijcard.2015.10.238.
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Keywords: Cardiovascular Conditions, Diagnostic Safety and Quality, Imaging, Primary Care, Decision Making
Patel R, Lim RP, Saric M
Diagnostic performance of cardiac magnetic resonance imaging and echocardiography in evaluation of cardiac and paracardiac masses.
The researchers evaluated the predictive value of echocardiography and cardiac magnetic resonance (CMR) imaging parameters to identify tumors and malignancy and to provide histopathologic diagnosis of cardiac masses. They found that CMR identified 6 masses missed on transthoracic echocardiography (4 of which were outside the heart) and provided significantly more correct histopathologic diagnoses compared to echocardiography (77 percent vs 43 percent).
AHRQ-funded; HS019473.
Citation: Patel R, Lim RP, Saric M .
Diagnostic performance of cardiac magnetic resonance imaging and echocardiography in evaluation of cardiac and paracardiac masses.
Am J Cardiol 2016 Jan;117(1):135-40. doi: 10.1016/j.amjcard.2015.10.014..
Keywords: Diagnostic Safety and Quality, Cardiovascular Conditions, Imaging, Cancer, Comparative Effectiveness