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Search All Research Studies
AHRQ Research Studies Date
Topics
- Adverse Drug Events (ADE) (1)
- Antibiotics (3)
- Antimicrobial Stewardship (1)
- Anxiety (1)
- Asthma (1)
- Behavioral Health (1)
- Case Study (1)
- Children/Adolescents (2)
- Chronic Conditions (1)
- Depression (1)
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- (-) Medication (6)
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- (-) Respiratory Conditions (6)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 6 of 6 Research Studies DisplayedJones YO, Hubbell BB, Thomson J
Things we do for no reason: systemic corticosteroids for wheezing in preschool-aged children.
This installment of the “Things We Do For No Reason” series presents and discusses a case study concerning the administration of systemic corticosteroids in a 4-year-old child presenting with wheezing, tachypnea, and respiratory distress. The authors conclude that current evidence does not support the routine use of systemic corticosteroids for preschool-aged children admitted for mild to moderate wheezing episodes, and that the patient in the introductory case would likely receive no clinical benefit from dexamethasone treatment.
AHRQ-funded; HS025138.
Citation: Jones YO, Hubbell BB, Thomson J .
Things we do for no reason: systemic corticosteroids for wheezing in preschool-aged children.
J Hosp Med 2019 Dec;14(12):774-76. doi: 10.12788/jhm.3255..
Keywords: Children/Adolescents, Respiratory Conditions, Asthma, Case Study, Shared Decision Making, Medication
Ulrich RJ, McClung D, Wang BR
Introduction of procalcitonin testing and antibiotic utilization for acute exacerbations of chronic obstructive pulmonary disease.
This study measured the amount of procalcitonin testing (PCT) done for hospital inpatients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD). PCT tests for presence of bacterial infection, which the majority of AECOPD inpatients did not have. Out of 238 AECOPD admissions, 31% had PCT performed. The patients who were tested were more likely to meet systemic inflammatory response syndrome (SIRS) criteria, require intensive-care unit (ICU)-level care, and have a longer length of stay compared with those not tested. However, testing was not associated with a decrease in total antibiotic days of therapy.
AHRQ-funded.
Citation: Ulrich RJ, McClung D, Wang BR .
Introduction of procalcitonin testing and antibiotic utilization for acute exacerbations of chronic obstructive pulmonary disease.
Infect Dis 2019 Jun 12;12:1178633719852626. doi: 10.1177/1178633719852626..
Keywords: Antibiotics, Chronic Conditions, Respiratory Conditions, Medication
Gong CL, Zangwill KM, Hay JW
Behavioral economics interventions to improve outpatient antibiotic prescribing for acute respiratory infections: a cost-effectiveness analysis.
Researchers sought to determine the cost-effectiveness of three behavioral economic interventions designed to reduce inappropriate antibiotic prescriptions for acute respiratory infections (ARIs). Provider education on guidelines for the appropriate ARI treatment is compared with suggested alternatives, which use computerized clinical decision support to suggest non-antibiotic treatment choices; accountable justification, which mandates free-text justification into the patient's electronic health record when antibiotics are prescribed; and peer comparison. The authors concluded that behavioral economics interventions can be cost-effective strategies for reducing inappropriate antibiotic prescriptions by reducing healthcare resource utilization.
AHRQ-funded; HS019913.
Citation: Gong CL, Zangwill KM, Hay JW .
Behavioral economics interventions to improve outpatient antibiotic prescribing for acute respiratory infections: a cost-effectiveness analysis.
J Gen Intern Med 2019 Jun;34(6):846-54. doi: 10.1007/s11606-018-4467-x..
Keywords: Antibiotics, Antimicrobial Stewardship, Medication, Practice Patterns, Healthcare Costs, Respiratory Conditions
Vashakidze SA, Kempker JA, Jakobia NA
Pulmonary function and respiratory health after successful treatment of drug-resistant tuberculosis.
This cross-sectional study examined outcomes of patients successfully treated for drug-resistant tuberculosis (DR-TB) in Tbilisi, Georgia. Participants had a chest X-ray, St. George Respiratory Quality (SGRQ) survey, and pulmonary function tests (PFTs). Median follow-up tie was 41 months for the 58 subjects. A high proportion of subjects had residual pulmonary impairment, especially if this was a recurrence of TB or severe radiological disease. Patients who underwent surgical resection (47%) showed improved lung function.
AHRQ-funded; HS025240.
Citation: Vashakidze SA, Kempker JA, Jakobia NA .
Pulmonary function and respiratory health after successful treatment of drug-resistant tuberculosis.
Int J Infect Dis 2019 May;82:66-72. doi: 10.1016/j.ijid.2019.02.039..
Keywords: Medication, Outcomes, Respiratory Conditions
Iyer AS, Holm KE, Bhatt SP
Symptoms of anxiety and depression and use of anxiolytic-hypnotics and antidepressants in current and former smokers with and without COPD - a cross sectional analysis of the COPDGene cohort.
This study compared the frequency of anxiety/depressive symptoms of current and former smokers with and without COPD and their use of anxiolytic-hypnotics/antidepressants. A cohort of 5331 current/former smokers were surveyed. About 25% of smokers with and without COPD had anxiety/depressive symptoms. Unmedicated smokers tended to be African American, male, have no health insurance, have severe-very severe COPD and higher respiratory symptoms/exacerbation history.
AHRQ-funded; HS023009; HS013852.
Citation: Iyer AS, Holm KE, Bhatt SP .
Symptoms of anxiety and depression and use of anxiolytic-hypnotics and antidepressants in current and former smokers with and without COPD - a cross sectional analysis of the COPDGene cohort.
J Psychosom Res 2019 Mar;118:18-26. doi: 10.1016/j.jpsychores.2019.01.002..
Keywords: Anxiety, Medication, Respiratory Conditions, Depression, Behavioral Health, Anxiety, Tobacco Use
Downes KJ, Rao MB, Kahill L
Daily serum creatinine monitoring promotes earlier detection of acute kidney injury in children and adolescents with cystic fibrosis.
The purpose of this study was to determine the impact of daily serum creatinine (SCr) measurement on amino-glycoside (AG)-associated acute kidney injury detection among patients with cystic fibrosis (CF). The study included 87 patients at a children’s hospital who received a total of 227 AG courses of 3 days or more.
AHRQ-funded; HS021114
Citation: Downes KJ, Rao MB, Kahill L .
Daily serum creatinine monitoring promotes earlier detection of acute kidney injury in children and adolescents with cystic fibrosis.
J Cyst Fibros. 2014 Jul;13(4):435-41. doi: 10.1016/j.jcf.2014.03.005..
Keywords: Adverse Drug Events (ADE), Antibiotics, Children/Adolescents, Medication, Respiratory Conditions