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AHRQ Research Studies Date
Topics
- Arthritis (1)
- Care Management (2)
- Case Study (1)
- Chronic Conditions (2)
- Comparative Effectiveness (1)
- Decision Making (2)
- Education: Patient and Caregiver (3)
- Elderly (4)
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- Healthcare Cost and Utilization Project (HCUP) (2)
- Healthcare Costs (1)
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- Healthcare Utilization (1)
- Health Information Technology (HIT) (2)
- Health Literacy (1)
- Injuries and Wounds (7)
- Medication (4)
- (-) Osteoporosis (16)
- Patient-Centered Healthcare (1)
- Patient-Centered Outcomes Research (1)
- Patient and Family Engagement (1)
- Prevention (1)
- Racial and Ethnic Minorities (1)
- Risk (4)
- Screening (2)
- U.S. Preventive Services Task Force (USPSTF) (1)
- Women (4)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 16 of 16 Research Studies DisplayedAdami G, Saag KG, Mudano G, Saag KG, Mudano AS
Factors associated with the contemplative stage of readiness to initiate osteoporosis treatment.
Osteoporos Int 2020 Jul;31(7):1283-90. doi: 10.1007/s00198-020-05312-4.
AHRQ-funded; HS023009.
Citation: Adami G, Saag KG, Mudano G, Saag KG, Mudano AS .
Factors associated with the contemplative stage of readiness to initiate osteoporosis treatment.
Osteoporos Int 2020 Jul;31(7):1283-90. doi: 10.1007/s00198-020-05312-4..
Keywords: Osteoporosis, Women, Decision Making
Chovatiya R, Silverberg JI
Association of pemphigus and pemphigoid with osteoporosis and pathological fractures.
Researchers sought to determine whether pemphigus and bullous pemphigoid (BP) are associated with osteoporosis and fractures in the US. Subjects for this cross-sectional study included adults with pemphigus or with BP from the 2006-2012 National Emergency Department Sample. The researchers found that, when compared to BP, pemphigus was associated with higher odds of osteopenia, osteoporosis, and fractures, particularly of the ulna and radius. Patients with pemphigus or BP as well as long-term systemic corticosteroid use had the highest odds of osteoporosis and fractures. The researchers suggested that patients with these conditions may benefit from increased screening for osteoporosis and interventions to prevent fractures.
AHRQ-funded; HS023011.
Citation: Chovatiya R, Silverberg JI .
Association of pemphigus and pemphigoid with osteoporosis and pathological fractures.
Arch Dermatol Res 2020 May;312(4):263-71. doi: 10.1007/s00403-019-02010-y..
Keywords: Healthcare Cost and Utilization Project (HCUP), Osteoporosis, Injuries and Wounds, Emergency Department
Lopez-Olivo MA, des Bordes JKA, Lin H
Comparison of multimedia and printed patient education tools for patients with osteoporosis: a 6-month randomized controlled trial.
Researchers compared the efficacy of adding a multimedia patient education tool involving video modeling to a printed educational booklet on osteoporosis. Participants in the randomized controlled trial were post-menopausal women with osteoporosis. The researchers found that both multimedia and printed tools increased knowledge and decreased decisional conflict to the same extent, and neither of the educational materials proved to be better than the other. For women with limited health literacy, receiving the booklet alone was more effective in reducing decisional conflict after 6 months than the addition of the multimedia tool.
AHRQ-funded; HS019354.
Citation: Lopez-Olivo MA, des Bordes JKA, Lin H .
Comparison of multimedia and printed patient education tools for patients with osteoporosis: a 6-month randomized controlled trial.
Osteoporos Int 2020 May;31(5):857-66. doi: 10.1007/s00198-019-05210-4..
Keywords: Education: Patient and Caregiver, Osteoporosis, Chronic Conditions, Women
Shaheen MS, Silverberg JI
Association of asthma with osteopenia, osteoporosis, osteomalacia, and fractures.
Previous studies that examined the relationship between asthma, osteoporosis, and pathologic fractures found conflicting results. The objective of this study was to determine whether asthma was associated with osteopenia, osteoporosis, osteomalacia, and fractures in U.S. adults. The investigators concluded that ED visits with asthma were associated with osteopenia, osteoporosis, osteomalacia, and pathologic fractures.
Citation: Shaheen MS, Silverberg JI .
Association of asthma with osteopenia, osteoporosis, osteomalacia, and fractures.
Allergy Asthma Proc 2020 Mar 1;41(2):112-19. doi: 10.2500/aap.2020.41.190035.
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Keywords: Healthcare Cost and Utilization Project (HCUP), Osteoporosis, Injuries and Wounds, Emergency Department
Fan T, Duffy M
Screening for osteoporosis to prevent fractures.
This case study provides case questions and answers related to the U.S. Preventive Services Task Force recommendations on screening for osteoporosis to prevent fractures. It is part of the “Putting Prevention into Practice” series.
AHRQ-authored.
Citation: Fan T, Duffy M .
Screening for osteoporosis to prevent fractures.
Am Fam Physician 2018 Nov 15;98(10):593-94..
Keywords: Case Study, Injuries and Wounds, Osteoporosis, Prevention, Screening
Hall SF, Wright NC, Wolinsky FD
The prevalence of overtreatment of osteoporosis: results from the PAADRN trial.
There is a robust body of literature addressing undertreatment in osteoporosis, but limited data addressing overtreatment. In this study, the investigators sought to understand overtreatment as this understanding is important to minimizing harm and decrease costs. The investigators found that in their sample of older adults, overuse of osteoporosis pharmacotherapy was only 8.1%. Nevertheless, they concluded, overtreatment exposed patients to possible risk with negligible chance of benefit and should be minimized.
AHRQ-funded; HS023009.
Citation: Hall SF, Wright NC, Wolinsky FD .
The prevalence of overtreatment of osteoporosis: results from the PAADRN trial.
Arch Osteoporos 2018 Sep 28;13(1):103. doi: 10.1007/s11657-018-0517-6..
Keywords: Osteoporosis, Decision Making, Medication, Elderly, Patient-Centered Healthcare, Patient and Family Engagement, Care Management
Danila MI, Outman RC, Rahn EJ
Evaluation of a multimodal, direct-to-patient educational intervention targeting barriers to osteoporosis care: a randomized clinical trial.
Osteoporosis treatment rates are declining, even among those with past fractures. Novel, low-cost approaches are needed to improve osteoporosis care. In this study, the investigators conducted a parallel group, controlled, randomized clinical trial evaluating a behavioral intervention for improving osteoporosis medication use. They found that the primary study outcome was self-report of osteoporosis medication use at 6 months. Other outcomes included calcium and vitamin D supplementation, bone mineral density (BMD) testing, readiness for behavioral change, and barriers to treatment.
AHRQ-funded; HS023009.
Citation: Danila MI, Outman RC, Rahn EJ .
Evaluation of a multimodal, direct-to-patient educational intervention targeting barriers to osteoporosis care: a randomized clinical trial.
J Bone Miner Res 2018 May;33(5):763-72. doi: 10.1002/jbmr.3395..
Keywords: Care Management, Education: Patient and Caregiver, Elderly, Healthcare Delivery, Osteoporosis
Noel SE, Mangano KM, Griffith JL
Prevalence of osteoporosis and low bone mass among Puerto Rican older adults.
The authors aimed to determine the prevalence of osteoporosis and low bone mass (LBM) among 953 Puerto Rican adults, aged 47 to 79 years and living on the US mainland, using data from the Boston Puerto Rican Osteoporosis Study (BPROS). They found that the overall prevalence of osteoporosis and LBM were 10.5% and 43.3% for participants in the BPROS, respectively. They conclude that their findings indicate a need to understand specific factors contributing to osteoporosis in Puerto Rican adults, particularly younger men, in order to provide important information to guide the development of culturally- and linguistically-tailored interventions to improve bone health in this understudied and high-risk population.
AHRQ-funded; HS023009.
Citation: Noel SE, Mangano KM, Griffith JL .
Prevalence of osteoporosis and low bone mass among Puerto Rican older adults.
J Bone Miner Res 2018 Mar;33(3):396-403. doi: 10.1002/jbmr.3315..
Keywords: Osteoporosis, Elderly, Racial and Ethnic Minorities
Lopez-Olivo MA, Ingleshwar A, Volk RJ
Development and pilot testing of multimedia patient education tools for patients with knee osteoarthritis, osteoporosis, and rheumatoid arthritis.
Researched developed multimedia educational tools that incorporated videos to help patients understand their chronic diseases including osteoporosis, osteoarthritis, and rheumatoid arthritis. Tools were developed in English and Spanish. A total of 60 patients (20 per disease) were recruited to see the videos and were interviewed after all. All participants gave them a favorable rating and felt it helped them understand the disease, the importance of taking their medications, and seeing their doctor regularly. They found the videos and accompanying materials easy to use and easy to understand.
AHRQ-funded; HS019354.
Citation: Lopez-Olivo MA, Ingleshwar A, Volk RJ .
Development and pilot testing of multimedia patient education tools for patients with knee osteoarthritis, osteoporosis, and rheumatoid arthritis.
Arthritis Care Res 2018 Feb;70(2):213-20. doi: 10.1002/acr.23271..
Keywords: Arthritis, Chronic Conditions, Education: Patient and Caregiver, Osteoporosis, Health Literacy
Amarnath AL, Franks P, Robbins JA
Underuse and overuse of osteoporosis screening in a regional health system: a retrospective cohort study.
The researchers aimed to determine the extent to which dual-energy x-ray absorptiometry (DXA) screening is used in accordance with USPSTF recommendations within a regional health system. They concluded that DXA screening was underused in women at increased fracture risk, including women age 65 and over. Meanwhile, DXA screening was common among women at low fracture risk, such as younger women without osteoporosis risk factors.
AHRQ-funded; HS022236.
Citation: Amarnath AL, Franks P, Robbins JA .
Underuse and overuse of osteoporosis screening in a regional health system: a retrospective cohort study.
J Gen Intern Med 2015 Dec;30(12):1733-40. doi: 10.1007/s11606-015-3349-8.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Screening, Osteoporosis, Healthcare Utilization, Risk
Crandall CJ, Hovey KM, Andrews CA
Bone mineral density as a predictor of subsequent wrist fractures: findings from the Women's Health Initiative Study.
This paper's objective was to examine associations between the Fracture Risk Assessment Tool (FRAX)-predicted risk of major osteoporotic fracture (MOF), bone mineral density (BMD), BMD change, and wrist fracture. Results showed that lumbar spine and femoral neck BMDs were associated with incident wrist fracture, but the FRAX threshold recommended to identify screening candidates did not identify the majority of women who subsequently experienced wrist fracture.
AHRQ-funded; HS023009.
Citation: Crandall CJ, Hovey KM, Andrews CA .
Bone mineral density as a predictor of subsequent wrist fractures: findings from the Women's Health Initiative Study.
J Clin Endocrinol Metab 2015 Nov;100(11):4315-24. doi: 10.1210/jc.2015-2568.
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Keywords: Injuries and Wounds, Osteoporosis, Risk, Women
Hernandez I, Zhang Y
Comparing clinical and economic outcomes of biologic and conventional medications in postmenopausal women with osteoporosis.
This study compared clinical and economic outcomes between teriparatide (monthly costs $1120) and bisphosphonates (monthly costs $14) among postmenopausal women with osteoporosis. It found that teriparatide users had higher risk of fracture and higher costs, compared with similar bisphosphonates users. The hazard ratios of fracture for teriparatide relative to bisphosphonates ranged from 1.37 to 2.12, depending on methods.
AHRQ-funded; HS018657.
Citation: Hernandez I, Zhang Y .
Comparing clinical and economic outcomes of biologic and conventional medications in postmenopausal women with osteoporosis.
J Eval Clin Pract 2015 Oct;21(5):840-7. doi: 10.1111/jep.12389.
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Keywords: Medication, Women, Osteoporosis, Healthcare Costs
LaFleur J, DuVall SL, Wilson T
Analysis of osteoporosis treatment patterns with bisphosphonates and outcomes among postmenopausal veterans.
This study evaluated bisphosphonate change behaviors (switching, discontinuing, or reinitiating) over time, as well as fractures and costs, among a large, national cohort of postmenopausal veterans. It found that most bisphosphonate patients discontinue treatment at some point, which did not significantly increase the risk of fracture in this majority non-high risk population. Bisphosphonate change behaviors were associated with significantly lower osteoporosis costs, but significantly higher total costs.
AHRQ-funded; HS018582.
Citation: LaFleur J, DuVall SL, Wilson T .
Analysis of osteoporosis treatment patterns with bisphosphonates and outcomes among postmenopausal veterans.
Bone 2015 Sep;78:174-85. doi: 10.1016/j.bone.2015.04.022..
Keywords: Osteoporosis, Medication, Elderly, Injuries and Wounds
LaFleur J, Steenhoek CL, Horne J
Comparing fracture absolute risk assessment (FARA) tools: an osteoporosis clinical informatics tool to improve identification and care of men at high risk of first fracture.
The researchers compared 2 fracture absolute risk assessment (FARA) tools for use with electronic health records (EHRs) to determine which would more accurately identify patients known to be high risk for fracture. They found that absolute fracture risk estimation with the VA-FARA is more predictive of a first fracture than the WHO’s eFRAX in male veterans when used in an EHR-based population screening tool.
AHRQ-funded; HS018582.
Citation: LaFleur J, Steenhoek CL, Horne J .
Comparing fracture absolute risk assessment (FARA) tools: an osteoporosis clinical informatics tool to improve identification and care of men at high risk of first fracture.
Ann Pharmacother 2015 May;49(5):506-14. doi: 10.1177/1060028015572819..
Keywords: Electronic Health Records (EHRs), Health Information Technology (HIT), Injuries and Wounds, Osteoporosis, Risk
Yun H, Delzell E, Saag KG
Fractures and mortality in relation to different osteoporosis treatments.
The researchers aimed to determine if fracture and mortality rates vary among patients initiating different osteoporosis medications. They found that IV ibandronate and calcitonin were associated with higher rates of some types of fracture when compared to IV zolendronic acid. The relatively high mortality associated with use of calcitonin may reflect the poorer health of users of this agent.
AHRQ-funded; HS018517.
Citation: Yun H, Delzell E, Saag KG .
Fractures and mortality in relation to different osteoporosis treatments.
Clin Exp Rheumatol 2015 May-Jun;33(3):302-9..
Keywords: Osteoporosis, Medication, Comparative Effectiveness, Patient-Centered Outcomes Research
Unni S, Yao Y, Milne N
An evaluation of clinical risk factors for estimating fracture risk in postmenopausal osteoporosis using an electronic medical record database.
The researchers sought to identify variables in an EMR database for calculating fracture risk Assessment (FRAX) score in a cohort of postmenopausal women, to estimate absolute fracture risk. They found that mean 10-year risk for any major fracture was 11.1 percent when bone mineral density (BMD) was used and 11.2 percent when BMI was used.
AHRQ-funded; HS0018582.
Citation: Unni S, Yao Y, Milne N .
An evaluation of clinical risk factors for estimating fracture risk in postmenopausal osteoporosis using an electronic medical record database.
Osteoporos Int 2015 Feb;26(2):581-7. doi: 10.1007/s00198-014-2899-7..
Keywords: Electronic Health Records (EHRs), Injuries and Wounds, Risk, Osteoporosis, Health Information Technology (HIT)