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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 5 of 5 Research Studies DisplayedBartsch SM, Taitel MS, DePasse JV
Epidemiologic and economic impact of pharmacies as vaccination locations during an influenza epidemic.
During an influenza epidemic, where early vaccination is crucial, pharmacies may be a resource to increase vaccine distribution reach and capacity. In this paper, the investigators utilized an agent-based model of the US and a clinical and economics outcomes model to simulate the impact of different influenza epidemics and the impact of utilizing pharmacies in addition to traditional (hospitals, clinic/physician offices, and urgent care centers) locations for vaccination for the year 2017.
AHRQ-funded; HS023317.
Citation: Bartsch SM, Taitel MS, DePasse JV .
Epidemiologic and economic impact of pharmacies as vaccination locations during an influenza epidemic.
Vaccine 2018 Nov 12;36(46):7054-63. doi: 10.1016/j.vaccine.2018.09.040..
Keywords: Healthcare Costs, Influenza, Provider: Pharmacist, Public Health, Vaccination
Wedlock PT, Mitgang EA, Siegmund SS
Dual-chamber injection device for measles-rubella vaccine: the potential impact of introducing varying sizes of the devices in 3 countries.
The purpose of this study was to identify the ideal size for dual-chamber injection devices used in routine immunization programs. Vaccine supply chain models of the Republic of Benin, the Republic of Mozambique, and Bihar were generated using the HERMES modeling software to simulate the effects of replacing a 10-dose lyophilized measles-rubella vaccine with single-dose, dual-chamber injection devices of varying sizes and prices. Optimal volume-per-dose was identified as either improving or causing no change in vaccine availability, wastage, or supply-chain costs in comparison to the existing program. The study concludes that a single-dose, dual-chamber measles-rubella injection device would need to be no larger than 5.2cm(3) to not significantly impair the flow of other vaccines.
AHRQ-funded; HS023317.
Citation: Wedlock PT, Mitgang EA, Siegmund SS .
Dual-chamber injection device for measles-rubella vaccine: the potential impact of introducing varying sizes of the devices in 3 countries.
Vaccine 2018 Sep 18;36(39):5879-85. doi: 10.1016/j.vaccine.2018.08.026..
Keywords: Public Health, Vaccination
de Montigny S, Adamson BJS, Masse BR
Projected effectiveness and added value of HIV vaccination campaigns in South Africa: a modeling study.
Sci Rep 2018 Apr 17;8(1):6066. doi: 10.1038/s41598-018-24268-4.
In this paper, the authors estimated the potential epidemiological and economic impact of HIV vaccine campaigns compared to continuous vaccination, assuming that vaccine efficacy was transient and dependent on immune response. The investigators concluded that results suggested a partially effective HIV vaccine would have substantial impact on the HIV epidemic in South Africa and offer good value if priced less than $105 for a five-dose series. They suggested that vaccination campaigns every two years may offer greater value for money than continuous vaccination reaching the same coverage level.
In this paper, the authors estimated the potential epidemiological and economic impact of HIV vaccine campaigns compared to continuous vaccination, assuming that vaccine efficacy was transient and dependent on immune response. The investigators concluded that results suggested a partially effective HIV vaccine would have substantial impact on the HIV epidemic in South Africa and offer good value if priced less than $105 for a five-dose series. They suggested that vaccination campaigns every two years may offer greater value for money than continuous vaccination reaching the same coverage level.
AHRQ-funded; HS013853.
Citation: de Montigny S, Adamson BJS, Masse BR .
Projected effectiveness and added value of HIV vaccination campaigns in South Africa: a modeling study.
Sci Rep 2018 Apr 17;8(1):6066. doi: 10.1038/s41598-018-24268-4..
Keywords: Health Services Research (HSR), Healthcare Costs, Human Immunodeficiency Virus (HIV), Public Health, Vaccination
Szilagyi PG, Schaffer S, Rand CM
School-located influenza vaccinations for adolescents: a randomized controlled trial.
In this study, the investigators aimed to evaluate the effect of school-located influenza vaccination (SLIV) on adolescents' influenza vaccination rates. In 2015-2016, they performed a cluster-randomized trial of adolescent SLIV in middle/high schools. They concluded that SLIV in this community increased influenza vaccination rates among adolescents attending suburban schools.
AHRQ-funded; HS021163.
Citation: Szilagyi PG, Schaffer S, Rand CM .
School-located influenza vaccinations for adolescents: a randomized controlled trial.
J Adolesc Health 2018 Feb;62(2):157-63. doi: 10.1016/j.jadohealth.2017.09.021..
Keywords: Children/Adolescents, Education, Influenza, Prevention, Public Health, Vaccination
Glanz JM, Kraus CR, Daley MF
Addressing parental vaccine concerns: engagement, balance, and timing.
The recent United States measles epidemic has sparked another contentious national discussion about childhood vaccination. Interventions to address this emerging public health issue are needed. The authors describe a framework by which web-based interventions can be used to help parents make evidence-based decisions about childhood vaccinations.
AHRQ-funded; HS021492.
Citation: Glanz JM, Kraus CR, Daley MF .
Addressing parental vaccine concerns: engagement, balance, and timing.
PLoS Biol 2015 Aug;13(8):e1002227. doi: 10.1371/journal.pbio.1002227..
Keywords: Vaccination, Children/Adolescents, Public Health, Education: Patient and Caregiver