National Healthcare Quality and Disparities Report
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AHRQ Research Studies Date
Topics
- Access to Care (1)
- Behavioral Health (1)
- Brain Injury (1)
- Caregiving (2)
- Case Study (1)
- Children/Adolescents (6)
- Chronic Conditions (3)
- Clinician-Patient Communication (1)
- Comparative Effectiveness (2)
- Decision Making (2)
- Disparities (1)
- Education: Patient and Caregiver (1)
- Elderly (2)
- Evidence-Based Practice (6)
- Guidelines (2)
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- Injuries and Wounds (1)
- Lifestyle Changes (2)
- Long-Term Care (1)
- Medication (3)
- Neurological Disorders (1)
- Nursing Homes (1)
- Obesity (1)
- Obesity: Weight Management (1)
- Outcomes (1)
- Patient-Centered Healthcare (1)
- Patient-Centered Outcomes Research (2)
- Patient Adherence/Compliance (1)
- Patient Experience (1)
- Patient Self-Management (1)
- Quality of Care (2)
- Quality of Life (1)
- Racial and Ethnic Minorities (1)
- Respiratory Conditions (8)
- Risk (1)
- Screening (2)
- Skin Conditions (3)
- (-) Sleep Problems (22)
- Surgery (1)
- Tobacco Use (1)
- U.S. Preventive Services Task Force (USPSTF) (2)
- Urban Health (1)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 22 of 22 Research Studies DisplayedWickwire EM, Schnyer DM, Germain A
Sleep, sleep disorders, and circadian health following mild traumatic brain injury in adults: review and research agenda.
A rapidly expanding scientific literature supports the frequent co-occurrence of sleep and circadian disturbances following mild traumatic brain injury (mTBI). In this paper, the authors review relevant literature and present a research agenda to 1) advance understanding of the reciprocal relationships between sleep and circadian factors and mTBI sequelae and 2) advance rapidly the development of sleep-related treatments in this population.
AHRQ-funded; HS024560.
Citation: Wickwire EM, Schnyer DM, Germain A .
Sleep, sleep disorders, and circadian health following mild traumatic brain injury in adults: review and research agenda.
J Neurotrauma 2018 Nov 15;35(22):2615-31. doi: 10.1089/neu.2017.5243..
Keywords: Sleep Problems, Brain Injury, Evidence-Based Practice
Hirayama A, Goto T, Faridi MK
Association of obstructive sleep apnoea with acute severity of chronic obstructive pulmonary disease exacerbation: a population-based study.
This retrospective cohort study investigated the association of coexistent obstructive sleep apnoea with acute severity markers (i.e. invasive positive pressure ventilation use and hospital length of stay) among adults hospitalised for acute exacerbation of chronic obstructive pulmonary disease.
AHRQ-funded; HS023305.
Citation: Hirayama A, Goto T, Faridi MK .
Association of obstructive sleep apnoea with acute severity of chronic obstructive pulmonary disease exacerbation: a population-based study.
Intern Med J 2018 Sep;48(9):1150-53. doi: 10.1111/imj.14016..
Keywords: Respiratory Conditions, Hospitalization, Sleep Problems, Chronic Conditions
Kline CE, Burke LE, Sereika SM
Bidirectional relationships between weight change and sleep apnea in a behavioral weight loss intervention.
This study examined the relationship between weight change and obstructive sleep apnea (OSA) in the context of behavioral weight loss intervention. A total of 114 adults who were overweight or obese participated in a 12-month behavioral weight loss intervention program from April 2012 to February 2015. Over half (58%) had OSA at the baseline. Those with OSA were found to lose less weight and were less adherent to daily calorie and activity goals. The results suggest that OSA screening should be used before attempting weight loss and also may indicate additional behavioral counseling.
AHRQ-funded; HS022989.
Citation: Kline CE, Burke LE, Sereika SM .
Bidirectional relationships between weight change and sleep apnea in a behavioral weight loss intervention.
Mayo Clin Proc 2018 Sep;93(9):1290-98. doi: 10.1016/j.mayocp.2018.04.026..
Keywords: Sleep Problems, Obesity: Weight Management, Obesity, Lifestyle Changes, Respiratory Conditions
Li JC, Fishbein A, Singam V
Sleep disturbance and sleep-related impairment in adults with atopic dermatitis: a cross-sectional study.
The aim of this prospective online questionnaire-based study was to determine the relationship between atopic dermatitis (AD) severity, sleep disturbance (SD), and sleep-related impairment (SRI). The investigators concluded that their study suggests that SD and SRI are common in adults with AD, particularly those with severe diseases. They suggest that sleep disturbances and SRI should be considered when assessing burden of AD and therapeutic decisions.
AHRQ-funded; HS023011.
Citation: Li JC, Fishbein A, Singam V .
Sleep disturbance and sleep-related impairment in adults with atopic dermatitis: a cross-sectional study.
Dermatitis 2018 Sep/Oct;29(5):270-77. doi: 10.1097/der.0000000000000401..
Keywords: Skin Conditions, Sleep Problems
Barone Gibbs B, Kline CE
When does sedentary behavior become sleep? A proposed framework for classifying activity during sleep-wake transitions.
The Sedentary Behavior Research Network recently published a consensus definition for sedentary. The authors of this paper indicated that further clarity around issues of classifying sedentary behavior while in bed is needed, specifically during sleep-wake transitions. In this paper they propose a framework for classifying activity during sleep-wake transitions.
AHRQ-funded; HS021162.
Citation: Barone Gibbs B, Kline CE .
When does sedentary behavior become sleep? A proposed framework for classifying activity during sleep-wake transitions.
Int J Behav Nutr Phys Act 2018 Aug 22;15(1):81. doi: 10.1186/s12966-018-0712-2..
Keywords: Lifestyle Changes, Sleep Problems
Harris VC, Links AR, Kim JM
Follow-up and time to treatment in an urban cohort of children with sleep-disordered breathing.
The purpose of this study was to evaluate follow-up and timing of sleep-disordered breathing diagnosis and treatment in urban children referred from primary care. Researchers found that half of the children referred for sleep-disordered breathing evaluation are lost to follow-up from primary care. Obstructive sleep apnea severity did not predict follow-up or timeliness of treatment. They conclude that these findings suggest social determinants may pose barriers to care in addition to the clinical burden of sleep-disordered breathing.
AHRQ-funded; HS022932.
Citation: Harris VC, Links AR, Kim JM .
Follow-up and time to treatment in an urban cohort of children with sleep-disordered breathing.
Otolaryngol Head Neck Surg 2018 Aug;159(2):371-78. doi: 10.1177/0194599818772035..
Keywords: Access to Care, Children/Adolescents, Disparities, Healthcare Delivery, Patient-Centered Healthcare, Quality of Care, Respiratory Conditions, Sleep Problems, Urban Health
Ye L, Richards KC
Sleep and long-term care.
This review describes the nature and consequences of sleep disturbances in long-term care (LTC), clinical assessment and management of sleep disturbances in LTC, and implications for future research and clinical practice.
AHRQ-funded; HS024330.
Citation: Ye L, Richards KC .
Sleep and long-term care.
Sleep Med Clin 2018 Mar;13(1):117-25. doi: 10.1016/j.jsmc.2017.09.011..
Keywords: Quality of Care, Long-Term Care, Nursing Homes, Sleep Problems
Fishbein AB, Mueller K, Kruse L
Sleep disturbance in children with moderate/severe atopic dermatitis: a case-control study.
The researchers sought to characterize sleep in a cohort of children with moderate-to-severe atopic dermatitis (AD) and to determine methods for assessment of sleep disturbance. In nineteen patients and nineteen controls, they found that patients with AD experienced wake after sleep onset (WASO) for 103 plus or minus 55 minutes as compared with 50 plus or minus 27 minutes in the controls. They had a higher frequency of restless sleep, daytime sleepiness, difficulty falling back to sleep at night, and teacher-reported daytime sleepiness. They concluded that children with moderate-to-severe AD experience more WASO and lower sleep efficiency than healthy controls but similar bedtime and wake time, sleep duration, and sleep onset latency.
AHRQ-funded; HS023011.
Citation: Fishbein AB, Mueller K, Kruse L .
Sleep disturbance in children with moderate/severe atopic dermatitis: a case-control study.
J Am Acad Dermatol 2018 Feb;78(2):336-41. doi: 10.1016/j.jaad.2017.08.043.
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Keywords: Children/Adolescents, Children/Adolescents, Skin Conditions, Sleep Problems
Sylvia LG, Chang WC, Kamali M
Sleep disturbance may impact treatment outcome in bipolar disorder: a preliminary investigation in the context of a large comparative effectiveness trial.
The purpose of this paper is to explore the potential impact of poor sleep at baseline on outcomes in a randomized effectiveness trial of quetiapine and lithium. Sixty-three percent of patients had baseline sleep disturbance. Individuals with sleep disturbance had worse bipolar illness severity, greater severity of depression, mania, anxiety, irritability, and psychosis, were less likely to have sustained response, and had more necessary clinical adjustments.
AHRQ-funded; HS019371.
Citation: Sylvia LG, Chang WC, Kamali M .
Sleep disturbance may impact treatment outcome in bipolar disorder: a preliminary investigation in the context of a large comparative effectiveness trial.
J Affect Disord 2018 Jan 1;225:563-68. doi: 10.1016/j.jad.2017.08.056.
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Keywords: Medication, Comparative Effectiveness, Behavioral Health, Patient-Centered Outcomes Research, Sleep Problems
Donovan LM, Rise PJ, Carson SS
Sleep disturbance in smokers with preserved pulmonary function and chronic obstructive pulmonary disease.
This study compared the magnitude and correlates of sleep disturbance between smokers with preserved pulmonary function and those with airflow obstruction. It found that among smokers with clinically identified chronic obstructive pulmonary disease (COPD), the severity of sleep disturbance is greater among those with preserved pulmonary function compared to those with airflow obstruction. Non-respiratory symptoms, such as depression, were associated with sleep disturbance in both groups.
AHRQ-funded; HS017894.
Citation: Donovan LM, Rise PJ, Carson SS .
Sleep disturbance in smokers with preserved pulmonary function and chronic obstructive pulmonary disease.
Ann Am Thorac Soc 2017 Dec;14(12):1836-43. doi: 10.1513/AnnalsATS.201706-453OC.
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Keywords: Respiratory Conditions, Sleep Problems, Tobacco Use, Chronic Conditions
McNellis RJ, Thomas S
AHRQ Author: McNellis RJ
Screening for obstructive sleep apnea in adults.
This case study involves a 52-year-old white man who presents to your office for a preventive health visit. He is overweight and has a history of hypertension and hyperlipidemia, which are stable and well controlled with medication. The study poses three multiple choice questions together with the U.S. Preventive Services Task Force recommendations and related background information.
AHRQ-authored.
Citation: McNellis RJ, Thomas S .
Screening for obstructive sleep apnea in adults.
Am Fam Physician 2017 Jul 15;96(2):123-24.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Sleep Problems, Screening, Evidence-Based Practice, Case Study, Guidelines
Fogelberg DJ, Leland NE, Blanchard J
Qualitative experience of sleep in individuals with spinal cord injury.
The objective of this study was to examine the experience of sleep among individuals with spinal cord injury (SCI). Sleep-related data were found in transcripts for 90 percent of the sample. Participants described diminished sleep duration and irregular sleep patterns. Several factors contributing to poor sleep were identified, including SCI-related circumstances and sleep environment. Participants also discussed how poor sleep affected occupational engagement.
AHRQ-funded; HS022907.
Citation: Fogelberg DJ, Leland NE, Blanchard J .
Qualitative experience of sleep in individuals with spinal cord injury.
OTJR 2017 Apr;37(2):89-97. doi: 10.1177/1539449217691978.
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Keywords: Sleep Problems, Quality of Life, Injuries and Wounds
Boss EF, Links AR, Saxton R
Parent experience of care and decision making for children who snore.
The researchers identified factors associated with parental experience and decision making in pediatric sleep-disordered breathing (SDB) and adenotonsillectomy (AT) surgery. They found that while clinical factors were influential for decision making, interpersonal factors helped parents feel comfortable and influenced their overall experience
AHRQ-funded; HS022932.
Citation: Boss EF, Links AR, Saxton R .
Parent experience of care and decision making for children who snore.
JAMA Otolaryngol Head Neck Surg 2017 Mar;143(3):218-25. doi: 10.1001/jamaoto.2016.2400.
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Keywords: Children/Adolescents, Sleep Problems, Caregiving, Patient Experience, Decision Making, Clinician-Patient Communication
Chinnadurai S, Jordan AK, Sathe NA
Tonsillectomy for obstructive sleep-disordered breathing: a meta-analysis.
This meta-analysis compared sleep, cognitive or behavioral, and health outcomes of tonsillectomy versus watchful waiting with supportive care in children with sleep-disordered breathing. It determined that, relative to watchful waiting, most studies reported better sleep-related outcomes in children who had a tonsillectomy.
AHRQ-funded; 290201500003I.
Citation: Chinnadurai S, Jordan AK, Sathe NA .
Tonsillectomy for obstructive sleep-disordered breathing: a meta-analysis.
Pediatrics 2017 Feb;139(2). doi: 10.1542/peds.2016-3491.
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Keywords: Children/Adolescents, Sleep Problems, Surgery, Evidence-Based Practice, Respiratory Conditions, Patient-Centered Outcomes Research, Evidence-Based Practice, Outcomes
Jonas DE, Amick HR, Feltner C
Screening for obstructive sleep apnea in adults: evidence report and systematic review for the US Preventive Services Task Force.
The effectiveness of stool-based colorectal cancer (CRC) screening is contingent on colonoscopy completion in patients with an abnormal fecal immunochemical test (FIT). This study found that FIT positive patients never referred to gastroenterology or who missed their appointment after referrals were more likely to have comorbid conditions and documented illicit substance use compared with patients who completed a colonoscopy.
AHRQ-funded; 290201200015I.
Citation: Jonas DE, Amick HR, Feltner C .
Screening for obstructive sleep apnea in adults: evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2017 Jan 24;317(4):415-33. doi: 10.1001/jama.2016.19635.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Screening, Sleep Problems, Evidence-Based Practice, Respiratory Conditions
Links AR, Tunkel DE, Boss EF
Stakeholder-engaged measure development for pediatric obstructive sleep-disordered breathing: the obstructive sleep-disordered breathing and adenotonsillectomy knowledge scale for parents.
The researchers developed a measure of parental knowledge about obstructive sleep-disordered breathing (oSDB) and adenotonsillectomy (AT). An 85-item prototype measure and 39-item modified measure were evaluated for consensus/approval and psychometric integrity Five themes (oSDB symptoms, treatment options, AT risks, anesthesia, and AT benefits) and 39 items composed the final scale.
AHRQ-funded; HS022932.
Citation: Links AR, Tunkel DE, Boss EF .
Stakeholder-engaged measure development for pediatric obstructive sleep-disordered breathing: the obstructive sleep-disordered breathing and adenotonsillectomy knowledge scale for parents.
JAMA Otolaryngol Head Neck Surg 2017 Jan;143(1):46-54. doi: 10.1001/jamaoto.2016.2681.
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Keywords: Children/Adolescents, Sleep Problems, Respiratory Conditions, Education: Patient and Caregiver, Decision Making
Riley K, Nazareno J, Malish S
24-hour care: work and sleep conditions of migrant Filipino live-in caregivers in Los Angeles.
The authors examined sleeping conditions and outcomes for live-in formal caregivers. They found that caregivers rated sleep quality as lower while at work and that over 40% reported excessive daytime sleepiness. They concluded that impacts on sleep quality pose risks for work-related injury and errors in patient care.
AHRQ-funded; HS000011.
Citation: Riley K, Nazareno J, Malish S .
24-hour care: work and sleep conditions of migrant Filipino live-in caregivers in Los Angeles.
Am J Ind Med 2016 Dec;59(12):1120-29. doi: 10.1002/ajim.22647.
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Keywords: Caregiving, Racial and Ethnic Minorities, Sleep Problems
Carballo NJ, Alessi CA, Martin JL
Perceived effectiveness, self-efficacy, and social support for oral appliance therapy among older veterans with obstructive sleep apnea.
Adherence to oral appliance therapy may be influenced by patients' perceived effectiveness of the therapy, self-efficacy, and availability of social support. The researchers examined these perceptions among older adults with obstructive sleep apnea who were prescribed oral appliance therapy. They concluded that only about one third of older adults perceived it as an effective treatment, were confident about oral appliance use, and/or believed that they would receive needed support.
AHRQ-funded; HS024379.
Citation: Carballo NJ, Alessi CA, Martin JL .
Perceived effectiveness, self-efficacy, and social support for oral appliance therapy among older veterans with obstructive sleep apnea.
Clin Ther 2016 Nov;38(11):2407-15. doi: 10.1016/j.clinthera.2016.09.008.
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Keywords: Elderly, Patient Adherence/Compliance, Sleep Problems, Patient Self-Management
Wilt TJ, MacDonald R, Brasure M
Pharmacologic treatment of insomnia disorder: an evidence report for a clinical practice guideline by the American College of Physicians.
The researchers assessed the benefits, harms, and comparative effectiveness of pharmacologic treatments for adults with insomnia disorder. Their review concluded that eszopiclone, zolpidem, and suvorexant may improve short-term global and sleep outcomes for adults with insomnia disorder, but the comparative effectiveness and long-term efficacy of pharmacotherapies for insomnia are not known.
AHRQ-funded; 290201200016I.
Citation: Wilt TJ, MacDonald R, Brasure M .
Pharmacologic treatment of insomnia disorder: an evidence report for a clinical practice guideline by the American College of Physicians.
Ann Intern Med 2016 Jul 18;165(2):103-12. doi: 10.7326/m15-1781.
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Keywords: Sleep Problems, Comparative Effectiveness, Medication, Evidence-Based Practice
Booth JN, 3rd, Behring M, Cantor RS
Zolpidem use and motor vehicle collisions in older drivers.
The association between current use of zolpidem-containing medications and motor vehicle collisions (MVCs) was evaluated among drivers of advanced age. Current zolpidem users, specifically women and individuals aged 80 years or more, had higher MVC rates than nonusers. Practitioners should consider behavioral treatment before initiating low doses of zolpidem.
AHRQ-funded; HS013852.
Citation: Booth JN, 3rd, Behring M, Cantor RS .
Zolpidem use and motor vehicle collisions in older drivers.
Sleep Med 2016 Apr;20:98-102. doi: 10.1016/j.sleep.2015.12.004.
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Keywords: Elderly, Medication, Sleep Problems
Wilson KC, Gould MK, Krishnan JA
An official American Thoracic Society workshop report. A framework for addressing multimorbidity in clinical practice guidelines for pulmonary disease, critical illness, and sleep disorders.
The American Thoracic Society convened a workshop to establish a strategy to address multimorbidity within clinical practice guidelines. This report describes a framework that addresses multimorbidity in each of the key steps of guideline development: topic selection, panel composition, identifying clinical questions, searching for and synthesizing evidence, rating the quality of that evidence, summarizing benefits and harms, formulating recommendations, and rating the strength of the recommendations.
AHRQ-funded; HS020672.
Citation: Wilson KC, Gould MK, Krishnan JA .
An official American Thoracic Society workshop report. A framework for addressing multimorbidity in clinical practice guidelines for pulmonary disease, critical illness, and sleep disorders.
Ann Am Thorac Soc 2016 Mar;13(3):S12-21. doi: 10.1513/AnnalsATS.201601-007ST.
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Keywords: Sleep Problems, Guidelines, Evidence-Based Practice, Chronic Conditions, Respiratory Conditions
Silverberg JI
Association between childhood eczema and headaches: an analysis of 19 US population-based studies.
The researchers sought to determine whether childhood eczema is associated with increased headaches and whether such association is related to fatigue or sleep disturbance. After analyzing national survey data from 401,002 children and adolescents, they found that eczema is associated with increased headaches in childhood, particularly in patients with severe disease accompanied by atopy, fatigue, and sleep disturbances.
AHRQ-funded; HS023011.
Citation: Silverberg JI .
Association between childhood eczema and headaches: an analysis of 19 US population-based studies.
J Allergy Clin Immunol 2016 Feb;137(2):492-99.e5. doi: 10.1016/j.jaci.2015.07.020.
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Keywords: Children/Adolescents, Neurological Disorders, Sleep Problems, Risk, Skin Conditions