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Search All Research Studies
AHRQ Research Studies Date
Topics
- Adverse Events (1)
- Cancer: Colorectal Cancer (1)
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- Comparative Effectiveness (1)
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- Diagnostic Safety and Quality (1)
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- (-) Patient-Centered Outcomes Research (5)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 5 of 5 Research Studies DisplayedFlory JH, Ukena JK, Floyd JS
Novel anti-glycemic drugs and reduction of cardiovascular risk in diabetes: expectations realized, promises unmet.
The researchers review evidence on cardiovascular risks and benefits of new treatments for type 2 diabetes mellitus. Their review reports new evidence suggesting that the newest diabetes drugs are safe from a cardiovascular perspective. Evidence on benefit from at least some members of the GLP-1 receptor agonist and SGLT-2 inhibitor classes is encouraging but not yet decisive.
AHRQ-funded; HS023898.
Citation: Flory JH, Ukena JK, Floyd JS .
Novel anti-glycemic drugs and reduction of cardiovascular risk in diabetes: expectations realized, promises unmet.
Curr Atheroscler Rep 2016 Dec;18(12):79. doi: 10.1007/s11883-016-0633-y.
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Keywords: Patient-Centered Outcomes Research, Medication, Diabetes, Cardiovascular Conditions, Risk
Dimou FM, Mehta HB, Adhikari D
The role of extended criteria donors in liver transplantation for nonalcoholic steatohepatitis.
The authors' objective was to determine the use of extended criteria donors (ECD) in patients with nonalcoholic steatohepatitis undergoing liver transplantation to stimulate a liver-specific predictive model for ECD use. They found that ECDs in nonalcoholic steatohepatitis were associated with similar overall survival but increased risk of graft failure. The authors concluded that creation of an easily calculated, liver-specific model similar to the Kidney Donor Profile Index may help risk stratify patients and improve organ allocation.
AHRQ-funded; HS022134.
Citation: Dimou FM, Mehta HB, Adhikari D .
The role of extended criteria donors in liver transplantation for nonalcoholic steatohepatitis.
Surgery 2016 Dec;160(6):1533-43. doi: 10.1016/j.surg.2016.06.051.
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Keywords: Transplantation, Patient-Centered Outcomes Research, Risk, Mortality, Outcomes
Simianu VV, Flum DR
Rethinking elective colectomy for diverticulitis: a strategic approach to population health.
The authors argue that a rethinking of elective colectomy should come from a patient-centered approach that considers the risks of recurrence, quality of life, patient wishes and experiences about surgical and medical treatment options as well as operative morbidity and risks.
AHRQ-funded; HS020025.
Citation: Simianu VV, Flum DR .
Rethinking elective colectomy for diverticulitis: a strategic approach to population health.
World J Gastroenterol 2014 Nov 28;20(44):16609-14. doi: 10.3748/wjg.v20.i44.16609..
Keywords: Patient-Centered Outcomes Research, Comparative Effectiveness, Surgery, Adverse Events, Risk
Desai RJ, Glynn RJ, Wang S
Performance of disease risk score matching in nested case-control studies: a simulation study.
The authors investigate whether or not matching on a disease risk score (DRS), which includes many confounders, results in greater precision than matching on only a few confounders. Their results suggest that DRS matching might increase the statistical efficiency of case-control studies, particularly when the outcome is rare.
AHRQ-funded; HS022193.
Citation: Desai RJ, Glynn RJ, Wang S .
Performance of disease risk score matching in nested case-control studies: a simulation study.
Am J Epidemiol 2016 May 15;183(10):949-57. doi: 10.1093/aje/kwv269.
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Keywords: Research Methodologies, Risk, Patient-Centered Outcomes Research
Abdelsattar ZM, Wong SL, Regenbogen SE
Colorectal cancer outcomes and treatment patterns in patients too young for average-risk screening.
The researchers investigated the national treatment patterns and outcomes of patients younger than 50 with colorectal cancer (CRC). They found that patients with CRC diagnosed at age <50 years are more likely to present with advanced-stage disease. However, they receive more aggressive therapy and achieve longer disease-specific survival, despite the greater percentage of patients with advanced-stage disease.
AHRQ-funded; HS000053; HS020937.
Citation: Abdelsattar ZM, Wong SL, Regenbogen SE .
Colorectal cancer outcomes and treatment patterns in patients too young for average-risk screening.
Cancer 2016 Mar 15;122(6):929-34. doi: 10.1002/cncr.29716.
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Keywords: Cancer: Colorectal Cancer, Diagnostic Safety and Quality, Patient-Centered Outcomes Research, Risk, Screening