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AHRQ Research Studies Date
Topics
- Adverse Events (2)
- Blood Clots (1)
- Blood Pressure (1)
- Cancer: Breast Cancer (1)
- (-) Cardiovascular Conditions (11)
- Children/Adolescents (1)
- Diabetes (2)
- Heart Disease and Health (4)
- Medication (2)
- Mortality (1)
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- Racial and Ethnic Minorities (2)
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- (-) Risk (11)
- Stroke (2)
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- U.S. Preventive Services Task Force (USPSTF) (1)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 11 of 11 Research Studies DisplayedYakoob MY, Micha R, Khatibzadeh S
Impact of dietary and metabolic risk factors on cardiovascular and diabetes mortality in South Asia: analysis from the 2010 Global Burden of Disease Study.
This article's objective is to quantify cardiovascular disease and diabetes deaths attributable to dietary and metabolic risks by country, age, sex, and time in South Asian countries. The authors used the 2010 Global Burden of Disease national surveys to characterize risk factor levels by age and sex. They found suboptimal diet to be the leading cuase of cardiometabolic mortality in 4 of 5 countries. They concluded that important similarities and differences are evident in cardiometabolic mortality burdens of modifiable dietary and metabolic risks across these countries, informing health policy and program priorities.
AHRQ-funded; HS000062.
Citation: Yakoob MY, Micha R, Khatibzadeh S .
Impact of dietary and metabolic risk factors on cardiovascular and diabetes mortality in South Asia: analysis from the 2010 Global Burden of Disease Study.
Am J Public Health 2016 Dec;106(12):2113-25. doi: 10.2105/ajph.2016.303368.
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Keywords: Cardiovascular Conditions, Diabetes, Mortality, Risk
Flory JH, Ukena JK, Floyd JS
Novel anti-glycemic drugs and reduction of cardiovascular risk in diabetes: expectations realized, promises unmet.
The researchers review evidence on cardiovascular risks and benefits of new treatments for type 2 diabetes mellitus. Their review reports new evidence suggesting that the newest diabetes drugs are safe from a cardiovascular perspective. Evidence on benefit from at least some members of the GLP-1 receptor agonist and SGLT-2 inhibitor classes is encouraging but not yet decisive.
AHRQ-funded; HS023898.
Citation: Flory JH, Ukena JK, Floyd JS .
Novel anti-glycemic drugs and reduction of cardiovascular risk in diabetes: expectations realized, promises unmet.
Curr Atheroscler Rep 2016 Dec;18(12):79. doi: 10.1007/s11883-016-0633-y.
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Keywords: Patient-Centered Outcomes Research, Medication, Diabetes, Cardiovascular Conditions, Risk
Strobel RJ, Liang Q, Zhang M
A preoperative risk model for postoperative pneumonia after coronary artery bypass grafting.
The authors developed a preoperative prediction model for postoperative pneumonia after coronary artery bypass grafting (CABG). In this article, they describe and discuss their model, which may be used to provide individualized risk estimation and to identify opportunities to reduce a patient's preoperative risk of pneumonia through prehabilitation.
AHRQ-funded; HS022535.
Citation: Strobel RJ, Liang Q, Zhang M .
A preoperative risk model for postoperative pneumonia after coronary artery bypass grafting.
Ann Thorac Surg 2016 Oct;102(4):1213-9. doi: 10.1016/j.athoracsur.2016.03.074.
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Keywords: Cardiovascular Conditions, Pneumonia, Adverse Events, Risk, Patient Safety
Kabra R, Girotra S, Vaughan Sarrazin M
Refining stroke prediction in atrial fibrillation patients by addition of African-American ethnicity to CHA2DS2-VASc score.
The authors hypothesized that the addition of African-American ethnicity to the CHA2DS2-VASc score might improve stroke prediction in patients with atrial fibrillation (AF). They found that, in patients over age 65 with newly diagnosed AF, the addition of ethnicity to CHA2DS2-VASc score significantly improved stroke prediction.
AHRQ-funded; HS023104.
Citation: Kabra R, Girotra S, Vaughan Sarrazin M .
Refining stroke prediction in atrial fibrillation patients by addition of African-American ethnicity to CHA2DS2-VASc score.
J Am Coll Cardiol 2016 Aug 2;68(5):461-70. doi: 10.1016/j.jacc.2016.05.044.
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Keywords: Stroke, Heart Disease and Health, Racial and Ethnic Minorities, Risk, Cardiovascular Conditions
Guirguis-Blake JM, Evans CV, Senger CA
Aspirin for the primary prevention of cardiovascular events: a systematic evidence review for the U.S. Preventive Services Task Force.
This is an update of a systematic review about the benefits of aspirin for the primary prevention of cardiovascular events in adults aged 40 years or older and to evaluate effect modification in subpopulations. It concluded that the beneficial effect of aspirin for the primary prevention of CVD is modest and also occurs at doses of 100 mg or less per day. Older adults seem to achieve a greater relative MI benefit.
AHRQ-funded; 290201200015.
Citation: Guirguis-Blake JM, Evans CV, Senger CA .
Aspirin for the primary prevention of cardiovascular events: a systematic evidence review for the U.S. Preventive Services Task Force.
Ann Intern Med 2016 Jun 21;164(12):804-13. doi: 10.7326/m15-2113.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Cardiovascular Conditions, Medication, Risk, Prevention
Bangalore S, Guo Y, Samadashvili Z
Revascularization in patients with multivessel coronary artery disease and severe left ventricular systolic dysfunction: everolimus-eluting stents versus coronary artery bypass graft surgery.
This study compared outcomes for patients with multivessel disease and severe left ventricular systolic dysfunction (ejection fraction </=35%) who underwent either percutaneous coronary intervention (PCI) with everolimus-eluting stent or coronary artery bypass graft surgery (CABG). It found that PCI with everolimus-eluting stent had comparable long-term survival in comparison with CABG. PCI was associated with higher risk of myocardial infarction (in those with incomplete revascularization) and repeat revascularization.
AHRQ-funded; HS023683.
Citation: Bangalore S, Guo Y, Samadashvili Z .
Revascularization in patients with multivessel coronary artery disease and severe left ventricular systolic dysfunction: everolimus-eluting stents versus coronary artery bypass graft surgery.
Circulation 2016 May 31;133(22):2132-40. doi: 10.1161/circulationaha.115.021168.
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Keywords: Cardiovascular Conditions, Heart Disease and Health, Surgery, Outcomes, Risk
O'Donoghue ML, Morrow DA, Cannon CP
Multimarker risk stratification in patients with acute myocardial infarction.
In this study, the investigators examined multimarker risk stratification in patients with acute myocardial infarction. They found that in patients with ST-elevation MI, a multimarker strategy that combines biomarkers across pathobiological axes of myocardial stress, myocyte necrosis, and inflammation provided incremental prognostic information for prediction of cardiovascular death or heart failure.
AHRQ-funded; HS023000.
Citation: O'Donoghue ML, Morrow DA, Cannon CP .
Multimarker risk stratification in patients with acute myocardial infarction.
J Am Heart Assoc 2016 May 20;5(5). doi: 10.1161/jaha.115.002586..
Keywords: Cardiovascular Conditions, Heart Disease and Health, Risk
Du XL, Zhang Y, Hardy D
Associations between hematopoietic growth factors and risks of venous thromboembolism, stroke, ischemic heart disease and myelodysplastic syndrome: findings from a large population-based cohort of women with breast cancer.
The researchers sought to determine the risk of venous thromboembolism (VTE), stroke, ischemic heart disease, and myelodysplastic syndrome (MDS) in association with the receipt of colony-stimulating factors (CSFs) and/or erythropoiesis-stimulating agents (ESAs) in women with breast cancer. They found that receipts of CSFs and ESAs were significantly associated with an increased risk of VTE in women with breast cancer.
AHRQ-funded; HS018956.
Citation: Du XL, Zhang Y, Hardy D .
Associations between hematopoietic growth factors and risks of venous thromboembolism, stroke, ischemic heart disease and myelodysplastic syndrome: findings from a large population-based cohort of women with breast cancer.
Cancer Causes Control 2016 May;27(5):695-707. doi: 10.1007/s10552-016-0742-5.
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Keywords: Blood Clots, Cancer: Breast Cancer, Cardiovascular Conditions, Risk, Stroke
Holcomb CN, Graham LA, Richman JS
The incremental risk of coronary stents on postoperative adverse events: a matched cohort study.
The objective of this study was to determine the incremental risk of coronary stents on adverse events in surgical patients and whether it varies over time from stent placement. It concluded that surgery after coronary stent placement is associated with an approximate 2 percent absolute risk for postoperative heart attack but no difference in mortality compared with nonstented matched controls.
AHRQ-funded; HS013852.
Citation: Holcomb CN, Graham LA, Richman JS .
The incremental risk of coronary stents on postoperative adverse events: a matched cohort study.
Ann Surg 2016 May;263(5):924-30. doi: 10.1097/sla.0000000000001246..
Keywords: Adverse Events, Risk, Surgery, Patient Safety, Heart Disease and Health, Cardiovascular Conditions
Silverberg JI
Atopic disease and cardiovascular risk factors in US children.
The researcher examined the impact of atopic disease on cardiovascular risk in children. He found that in multivariable models, pediatric asthma and hay fever were associated with higher odds of overweight and obesity, hypertension, and hyperlipidemia, but not diabetes. However, eczema was associated with higher odds of overweight and obesity, but not hypertension, hyperlipidemia, or diabetes.
AHRQ-funded; HS023011.
Citation: Silverberg JI .
Atopic disease and cardiovascular risk factors in US children.
J Allergy Clin Immunol 2016 Mar;137(3):938-40.e1. doi: 10.1016/j.jaci.2015.09.012.
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Keywords: Cardiovascular Conditions, Risk, Children/Adolescents, Children/Adolescents, Children/Adolescents
Booth JN, 3rd, Redmond N, Sims M
The association of reduced lung function with blood pressure variability in African Americans: data from the Jackson Heart Study.
The reseaerchers evaluated the association between percent predicted lung-function and 24-hour blood pressure variability (BPV) in 1008 African Americans enrolled in the Jackson Heart Study who underwent ambulatory blood pressure (BP) monitoring. They found that lung-function was not associated with increased 24-hour BPV.
AHRQ-funded; HS023009.
Citation: Booth JN, 3rd, Redmond N, Sims M .
The association of reduced lung function with blood pressure variability in African Americans: data from the Jackson Heart Study.
BMC Cardiovasc Disord 2016 Jan 12;16:6. doi: 10.1186/s12872-015-0182-2.
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Keywords: Cardiovascular Conditions, Blood Pressure, Racial and Ethnic Minorities, Risk, Respiratory Conditions