National Healthcare Quality and Disparities Report
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AHRQ Research Studies Date
Topics
- Adverse Drug Events (ADE) (1)
- Antibiotics (1)
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- Cancer: Colorectal Cancer (1)
- (-) Care Management (6)
- Chronic Conditions (1)
- Diabetes (1)
- Digestive Disease and Health (1)
- Elderly (1)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 6 of 6 Research Studies DisplayedZullo AR, Dore DD, Gutman R
National glucose-lowering treatment complexity is greater in nursing home residents than community-dwelling adults.
This letter describes common glucose-lowering medication usage patterns for a national cross-section of U.S. adults aged 65 and older residing in nursing home (NH) and community settings from 2007 to 2010. The study results suggest that continued efforts are warranted to improve glucose-lowering medication management and simplify treatment regimens in the NH; that the relative importance of CER questions regarding specific glucose-lowering treatments may differ according to the care setting; and that CER studies of glucose-lowering treatments in older adults must address the combination use of medications, especially in NH residents.
AHRQ-funded; HS022998.
Citation: Zullo AR, Dore DD, Gutman R .
National glucose-lowering treatment complexity is greater in nursing home residents than community-dwelling adults.
J Am Geriatr Soc 2016 Nov;64(11):e233-e35. doi: 10.1111/jgs.14485.
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Keywords: Care Management, Chronic Conditions, Diabetes, Elderly, Medication, Nursing Homes
Gaither JR, Goulet JL, Becker WC
The effect of substance use disorders on the association between guideline-concordant long-term opioid therapy and all-cause mortality.
The objective of this study was to determine whether the presence of a substance use disorder (SUD) modifies the association between guideline-concordant care and 1-year all-cause mortality among patients receiving long-term opioid therapy (LtOT) for pain. It found that for clinicians prescribing LtOT to patients with untreated SUDs, engaging patients with psychotherapeutic and SUD treatment services may reduce mortality.
AHRQ-funded; U19 HS021112.
Citation: Gaither JR, Goulet JL, Becker WC .
The effect of substance use disorders on the association between guideline-concordant long-term opioid therapy and all-cause mortality.
J Addict Med 2016 Nov/Dec;10(6):418-28. doi: 10.1097/adm.0000000000000255.
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Keywords: Care Management, Medication, Mortality, Substance Abuse, Opioids, Patient-Centered Outcomes Research
Gernant SA, Snyder ME, Jaynes H
The effectiveness of pharmacist-provided telephonic medication therapy management on emergency department utilization in home health patients.
This article's objective is to evaluate the effectiveness of a telephonic medication therapy management (MTM) service on reducing emergency department utilization within a Medicare-insured home health population. The authors found that this pharmacist-delivered telephonic medication therapy management program did not decrease emergency department utilization overall but may further reduce the such risk among patients who are at lower risk of utilization.
AHRQ-funded; HS022119.
Citation: Gernant SA, Snyder ME, Jaynes H .
The effectiveness of pharmacist-provided telephonic medication therapy management on emergency department utilization in home health patients.
J Pharm Technol 2016 Oct 1;32(5):179-84. doi: 10.1177/8755122516660376.
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Keywords: Care Management, Emergency Department, Medication, Patient-Centered Healthcare, Patient-Centered Outcomes Research, Prevention, Provider: Pharmacist, Provider
Haggerty CL, Totten PA, Tang G
Identification of novel microbes associated with pelvic inflammatory disease and infertility.
The authors examined the relationship between select novel bacteria, pelvic inflammatory disease (PID), and long-term sequelae. They demonstrated that S. sanguinegens, S. amnionii, BVAB1 and A. vaginae are associated with PID and suggested that optimal antibiotic regimens for PID may require coverage of novel bacterial vaginosis-associated microbes.
AHRQ-funded; HS008358.
Citation: Haggerty CL, Totten PA, Tang G .
Identification of novel microbes associated with pelvic inflammatory disease and infertility.
Sex Transm Infect 2016 Sep;92(6):441-6. doi: 10.1136/sextrans-2015-052285.
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Keywords: Antibiotics, Care Management, Medication, Women
Thompson KD, Connor SJ, Walls DM
Patients with ulcerative colitis are more concerned about complications of their disease than side effects of medications.
The survey’s aim was to better understand what aspects of ulcerative colitis (UC) and UC management, are most concerning to patients, and how they would like to be informed about treatment options. It found that most patients (87 percent) wanted to share treatment decision making with their doctors. Patients were most concerned about the risk of colorectal cancer (37 percent), and the possible need for an ileostomy (29 percent).
AHRQ-funded; HS021747.
Citation: Thompson KD, Connor SJ, Walls DM .
Patients with ulcerative colitis are more concerned about complications of their disease than side effects of medications.
Inflamm Bowel Dis 2016 Apr;22(4):940-7. doi: 10.1097/mib.0000000000000740.
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Keywords: Adverse Drug Events (ADE), Cancer, Cancer: Colorectal Cancer, Care Management, Medication
Stein BN, Pellish RS, Thompson KD
Using therapeutic drug monitoring to identify variable infliximab metabolism in an individual patient with ulcerative colitis.
In this case report, the authors demonstrate how therapeutic drug monitoring can be used to personalize a dosing regimen to ensure appropriate induction, and to safely deescalate therapy after remission is achieved. By identifying a change in drug clearance in an individual patient over time, they were able to attain significant cost savings despite the high price of serially measured drug and antibody concentrations.
AHRQ-funded; HS021747.
Citation: Stein BN, Pellish RS, Thompson KD .
Using therapeutic drug monitoring to identify variable infliximab metabolism in an individual patient with ulcerative colitis.
J Clin Gastroenterol 2016 Jan;50(1):66-8. doi: 10.1097/mcg.0000000000000370.
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Keywords: Care Management, Digestive Disease and Health, Quality of Care, Medication