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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 10 of 10 Research Studies DisplayedGuise JM, Savitz LA, Friedman CP
Mind the gap: putting evidence into practice in the era of learning health systems.
This paper discusses two main mechanisms to close the evidence-to-practice gap: (1) integrating Learning Health System (LHS) results with existing systematic review evidence and (2) providing this combined evidence in a standardized, computable data format.
AHRQ-funded; 29020120004C.
Citation: Guise JM, Savitz LA, Friedman CP .
Mind the gap: putting evidence into practice in the era of learning health systems.
J Gen Intern Med 2018 Dec;33(12):2237-39. doi: 10.1007/s11606-018-4633-1..
Keywords: Evidence-Based Practice, Healthcare Delivery, Learning Health Systems, Implementation
Davis MM, Lindberg P, Cross S
Aligning systems science and community-based participatory research: a case example of the Community Health Advocacy and Research Alliance (CHARA).
In this article, the investigators explored opportunities to utilize concepts from systems science to understand the development, evolution, and sustainability of 1 community-based participatory research partnership: The Community Health Advocacy and Research Alliance (CHARA). Their goal was to highlight CHARA as a case for applying the complementary approaches of CBPR and systems science to (1) improve academic/community partnership functioning and sustainability, (2) ensure that research addresses the priorities and needs of end users, and (3) support more timely application of scientific discoveries into routine practice.
AHRQ-funded; HS022981.
Citation: Davis MM, Lindberg P, Cross S .
Aligning systems science and community-based participatory research: a case example of the Community Health Advocacy and Research Alliance (CHARA).
J Clin Transl Sci 2018 Oct;2(5):280-88. doi: 10.1017/cts.2018.334..
Keywords: Learning Health Systems, Research Methodologies
Harrison MI, Grantham S
AHRQ Author: Harrison MI
Learning from implementation setbacks: identifying and responding to contextual challenges.
The authors addressed organizational learning about implementation context during setbacks to primary care redesign in an ambulatory system. They found that redesigned teams were not implemented as widely or rapidly as anticipated and did not deliver hoped-for gains in operational metrics; however, team redesign was leading to improvements in chronic care and prevention and eased provider burden. Redesign and system leaders engaged in more thorough organizational learning. Their responses to challenges helped to strengthen the redesign's prospects, improved the delivery system's position in its labor market, and helped the system prepare to meet emerging requirements for value-based care and population health.
AHRQ-authored; AHRQ-funded; 2902010000341.
Citation: Harrison MI, Grantham S .
Learning from implementation setbacks: identifying and responding to contextual challenges.
Learn Health Syst 2018 Oct;2(4):e10068. doi: 10.1002/lrh2.10068..
Keywords: Organizational Change, Learning Health Systems, Health Systems, Primary Care: Models of Care, Primary Care, Ambulatory Care and Surgery, Implementation
Forrest CB, Chesley FD, Tregear ML
AHRQ Author: Chesley FD, Mistry KB
Development of the learning health system researcher core competencies.
The purpose of this study was to develop core competencies for learning health system (LHS) researchers to guide the development of training programs. The investigators found that the iterative development process yielded seven competency domains: (1) systems science; (2) research questions and standards of scientific evidence; (3) research methods; (4) informatics; (5) ethics of research and implementation in health systems; (6) improvement and implementation science; and (7) engagement, leadership, and research management.
AHRQ-authored; AHRQ-funded; 290201200017I.
Citation: Forrest CB, Chesley FD, Tregear ML .
Development of the learning health system researcher core competencies.
Health Serv Res 2018 Aug;53(4):2615-32. doi: 10.1111/1475-6773.12751..
Keywords: Education: Continuing Medical Education, Learning Health Systems, Training
Moffatt-Bruce S, Huerta T, Gaughan A
IDEA4PS: the development of a research-oriented learning healthcare system.
In this paper, the authors present the approach of one academic medical center in becoming a research-oriented Learning Healthcare System (ro-LHS). By reframing the role of research in improving outcomes, the organization was able to move beyond its focus on quality improvement to foster a culture in which feedback informs practice and research drives improvement.
AHRQ-funded; HS024091.
Citation: Moffatt-Bruce S, Huerta T, Gaughan A .
IDEA4PS: the development of a research-oriented learning healthcare system.
Am J Med Qual 2018 Jul;33(4):420-25. doi: 10.1177/1062860617751044..
Keywords: Health Services Research (HSR), Learning Health Systems, Outcomes, Quality Improvement
Mullins CD, Wingate LT, Edwards HA
Transitioning from learning healthcare systems to learning health care communities.
The learning healthcare system (LHS) model framework has three core, foundational components. These include an infrastructure for health-related data capture, care improvement targets and a supportive policy environment. This paper discusses transitioning from learning healthcare systems to learning healthcare communities.
AHRQ-funded; HS022135.
Citation: Mullins CD, Wingate LT, Edwards HA .
Transitioning from learning healthcare systems to learning health care communities.
J Comp Eff Res 2018 Jun;7(6):603-14. doi: 10.2217/cer-2017-0105..
Keywords: Community-Based Practice, Healthcare Delivery, Learning Health Systems, Patient-Centered Healthcare
Kamal AH, Kirkland KB, Meier DE
A person-centered, registry-based learning health system for palliative care: a path to coproducing better outcomes, experience, value, and science.
In this paper, the authors discuss measurement of the impact of palliative care, which is critical for determining what works for which patients in what settings, to learn, improve care, and ensure access to high value care for people with serious illness. The authors described an approach to codesigning and implementing a palliative care registry that functions as a learning health system, by combining patient and family inputs and clinical data to support person-centered care, quality improvement, accountability, transparency, and scientific research.
AHRQ-funded; HS023681.
Citation: Kamal AH, Kirkland KB, Meier DE .
A person-centered, registry-based learning health system for palliative care: a path to coproducing better outcomes, experience, value, and science.
J Palliat Med 2018 Mar;21(S2):S61-s67. doi: 10.1089/jpm.2017.0354..
Keywords: Palliative Care, Patient-Centered Healthcare, Patient-Centered Outcomes Research, Outcomes, Learning Health Systems, Registries, Patient and Family Engagement
Nix M, McNamara P, Genevro J
AHRQ Author: Nix M, McNamara P, Genevro J, Vargas N, Mistry K, Fournier A, Shofer M, Lomotan E, Miller T, Ricciardi R, Bierman AS
Learning collaboratives: Insights and a new taxonomy from AHRQ's two decades of experience.
The authors examined AHRQ's experience with learning collaboratives to characterize their attributes, identify factors that might contribute to their success or failure, and assess the challenges they encountered. Building on the literature and insights from AHRQ's experience, they propose a taxonomy that can offer guidance to decision makers and funders about the factors they should consider in developing collaboratives.
AHRQ-authored.
Citation: Nix M, McNamara P, Genevro J .
Learning collaboratives: Insights and a new taxonomy from AHRQ's two decades of experience.
Health Aff 2018 Feb;37(2):205-12. doi: 10.1377/hlthaff.2017.1144.
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Keywords: Learning Health Systems, Health Systems, Quality Improvement, Quality of Care, Healthcare Delivery
Franklin P, Chenok K, Lavalee D
Framework to guide the collection and use of patient-reported outcome measures in the learning healthcare system.
Web-based collection of patient-reported outcome measures (PROMs) in clinical practice is expanding rapidly as electronic health records include web portals for patients to report standardized assessments of their symptoms. As the value of PROMs in patient care expands, a framework to guide the implementation planning, collection, and use of PROs to serve multiple goals and stakeholders is needed. In this study, researchers identified diverse clinical, quality, and research settings where PROMs have been successfully integrated into care and routinely collected and analyzed drivers of successful implementation.
AHRQ-funded; HS022789.
Citation: Franklin P, Chenok K, Lavalee D .
Framework to guide the collection and use of patient-reported outcome measures in the learning healthcare system.
eGEMS 2017 Sep 4;5(1):17. doi: 10.5334/egems.227..
Keywords: Learning Health Systems, Health Systems, Electronic Health Records (EHRs), Health Information Technology (HIT), Web-Based, Patient-Centered Healthcare
Ramsey LB, Mizuno T, Vinks AA
Learning health systems as facilitators of precision medicine.
To illustrate the concept of the Learning Health System, the authors of this paper describe the example of the ImproveCareNow Network and use a network case study to illustrate how the concept of precision medicine can be achieved through a Learning Health System in a real-world clinical environment.
AHRQ-funded; HS020024; HS016957.
Citation: Ramsey LB, Mizuno T, Vinks AA .
Learning health systems as facilitators of precision medicine.
Clin Pharmacol Ther 2017 Mar;101(3):359-67. doi: 10.1002/cpt.594..
Keywords: Learning Health Systems, Research Methodologies