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AHRQ Research Studies Date
Topics
- Arthritis (2)
- Cancer (1)
- Chronic Conditions (1)
- Decision Making (1)
- Diagnostic Safety and Quality (1)
- Disparities (2)
- Education: Patient and Caregiver (1)
- Elderly (1)
- Electronic Health Records (EHRs) (1)
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- (-) Osteoporosis (12)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 12 of 12 Research Studies DisplayedAdami G, Saag KG, Mudano G, Saag KG, Mudano AS
Factors associated with the contemplative stage of readiness to initiate osteoporosis treatment.
Osteoporos Int 2020 Jul;31(7):1283-90. doi: 10.1007/s00198-020-05312-4.
AHRQ-funded; HS023009.
Citation: Adami G, Saag KG, Mudano G, Saag KG, Mudano AS .
Factors associated with the contemplative stage of readiness to initiate osteoporosis treatment.
Osteoporos Int 2020 Jul;31(7):1283-90. doi: 10.1007/s00198-020-05312-4..
Keywords: Osteoporosis, Women, Decision Making
Chovatiya R, Silverberg JI
Association of pemphigus and pemphigoid with osteoporosis and pathological fractures.
Researchers sought to determine whether pemphigus and bullous pemphigoid (BP) are associated with osteoporosis and fractures in the US. Subjects for this cross-sectional study included adults with pemphigus or with BP from the 2006-2012 National Emergency Department Sample. The researchers found that, when compared to BP, pemphigus was associated with higher odds of osteopenia, osteoporosis, and fractures, particularly of the ulna and radius. Patients with pemphigus or BP as well as long-term systemic corticosteroid use had the highest odds of osteoporosis and fractures. The researchers suggested that patients with these conditions may benefit from increased screening for osteoporosis and interventions to prevent fractures.
AHRQ-funded; HS023011.
Citation: Chovatiya R, Silverberg JI .
Association of pemphigus and pemphigoid with osteoporosis and pathological fractures.
Arch Dermatol Res 2020 May;312(4):263-71. doi: 10.1007/s00403-019-02010-y..
Keywords: Healthcare Cost and Utilization Project (HCUP), Osteoporosis, Injuries and Wounds, Emergency Department
Lopez-Olivo MA, des Bordes JKA, Lin H
Comparison of multimedia and printed patient education tools for patients with osteoporosis: a 6-month randomized controlled trial.
Researchers compared the efficacy of adding a multimedia patient education tool involving video modeling to a printed educational booklet on osteoporosis. Participants in the randomized controlled trial were post-menopausal women with osteoporosis. The researchers found that both multimedia and printed tools increased knowledge and decreased decisional conflict to the same extent, and neither of the educational materials proved to be better than the other. For women with limited health literacy, receiving the booklet alone was more effective in reducing decisional conflict after 6 months than the addition of the multimedia tool.
AHRQ-funded; HS019354.
Citation: Lopez-Olivo MA, des Bordes JKA, Lin H .
Comparison of multimedia and printed patient education tools for patients with osteoporosis: a 6-month randomized controlled trial.
Osteoporos Int 2020 May;31(5):857-66. doi: 10.1007/s00198-019-05210-4..
Keywords: Education: Patient and Caregiver, Osteoporosis, Chronic Conditions, Women
Shaheen MS, Silverberg JI
Association of asthma with osteopenia, osteoporosis, osteomalacia, and fractures.
Previous studies that examined the relationship between asthma, osteoporosis, and pathologic fractures found conflicting results. The objective of this study was to determine whether asthma was associated with osteopenia, osteoporosis, osteomalacia, and fractures in U.S. adults. The investigators concluded that ED visits with asthma were associated with osteopenia, osteoporosis, osteomalacia, and pathologic fractures.
Citation: Shaheen MS, Silverberg JI .
Association of asthma with osteopenia, osteoporosis, osteomalacia, and fractures.
Allergy Asthma Proc 2020 Mar 1;41(2):112-19. doi: 10.2500/aap.2020.41.190035.
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Keywords: Healthcare Cost and Utilization Project (HCUP), Osteoporosis, Injuries and Wounds, Emergency Department
Wright NC, Melton ME, Sohail M
Race plays a role in the knowledge, attitudes, and beliefs of women with osteoporosis.
This study examined racial disparities in knowledge of osteoporosis among women aged 65 and over with osteoporosis. Focus groups were created with a total of 48 women (36 white, 12 African American) enrolled. A knowledge scale called “Osteoporosis & You” was used to compare scores. White women had a mean score of 7.8 versus African American women who scored a mean of 6.6 out of 10 on the scale. The “powerful others” domain was significantly higher among African Americans versus white women as well. These racial differences can impact bone health and indicated a need to improve education and awareness about osteoporosis among African American women.
AHRQ-funded; HS023009.
Citation: Wright NC, Melton ME, Sohail M .
Race plays a role in the knowledge, attitudes, and beliefs of women with osteoporosis.
J Racial Ethn Health Disparities 2019 Aug;6(4):707-18. doi: 10.1007/s40615-019-00569-w..
Keywords: Disparities, Racial and Ethnic Minorities, Osteoporosis, Women
Fink HA, MacDonald R, Forte ML
Long-term drug therapy and drug discontinuations and holidays for osteoporosis fracture prevention: a systematic review.
Optimal long-term osteoporosis drug treatment (ODT) is uncertain. The purpose of this study was to summarize the effects of long-term ODT and ODT discontinuation and holidays. The investigators concluded that: long-term alendronate and zoledronic acid therapies reduce fracture risk in women with osteoporosis; long-term bisphosphonate treatment may increase risk for rare adverse events, and continuing treatment beyond 3 to 5 years may reduce risk for vertebral fractures; and long-term hormone therapy reduces hip fracture risks but has serious harms.
AHRQ-funded; 290201500008I.
Citation: Fink HA, MacDonald R, Forte ML .
Long-term drug therapy and drug discontinuations and holidays for osteoporosis fracture prevention: a systematic review.
Ann Intern Med 2019 Jul 2;171(1):37-50. doi: 10.7326/m19-0533.
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Keywords: Evidence-Based Practice, Injuries and Wounds, Medication, Osteoporosis, Outcomes, Patient-Centered Outcomes Research, Prevention
Cram P, Saag KG, Lou Y
Racial differences and disparities in osteoporosis-related bone health: results from the PAADRN randomized controlled trial.
The researchers examined whether providing dual-energy x-ray absorptiometry (DXA) test results directly to patients might reduce or eliminate racial differences in osteoporosis-related health care. They found that black women were still less likely to know their actual DXA result and less likely to be on guideline-concordant therapy, but black women had greater patient activation.
AHRQ-funded; HS023009.
Citation: Cram P, Saag KG, Lou Y .
Racial differences and disparities in osteoporosis-related bone health: results from the PAADRN randomized controlled trial.
Med Care 2017 Jun;55(6):561-68. doi: 10.1097/mlr.0000000000000718.
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Keywords: Racial and Ethnic Minorities, Disparities, Osteoporosis, Health Status
Wright NC, Delzell ES, Smith WK
Improving medical record retrieval for validation studies in Medicare data.
The purpose of the study is to describe medical record retrieval for a study validating claims-based algorithms used to identify seven adverse events of special interest (AESI) in a Medicare population. It concluded that the national medical record validation study of claims-based algorithms produced a modest retrieval rate. The medical record procedures outlined in this paper could have led to the improved retrieval from the researchers’ previous medical record retrieval study.
AHRQ-funded; HS023009.
Citation: Wright NC, Delzell ES, Smith WK .
Improving medical record retrieval for validation studies in Medicare data.
Pharmacoepidemiol Drug Saf 2017 Apr;26(4):393-401. doi: 10.1002/pds.4131.
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Keywords: Medicare, Electronic Health Records (EHRs), Osteoporosis, Elderly
Wright NC, Saag KG, Dawson-Hughes B
The impact of the new National Bone Health Alliance (NBHA) diagnostic criteria on the prevalence of osteoporosis in the USA.
This study evaluated the prevalence of osteoporosis using the osteoporosis diagnostic criteria developed by the National Bone Health Alliance (NBHA), which includes qualified fractures, FRAX score in addition to bone mineral density (BMD). The study found that 16% of men and 29.9% of women 50+ have osteoporosis based on the NBHA diagnostic criteria.
AHRQ-funded; HS023009.
Citation: Wright NC, Saag KG, Dawson-Hughes B .
The impact of the new National Bone Health Alliance (NBHA) diagnostic criteria on the prevalence of osteoporosis in the USA.
Osteoporos Int 2017 Apr;28(4):1225-32. doi: 10.1007/s00198-016-3865-3..
Keywords: Diagnostic Safety and Quality, Injuries and Wounds, Osteoporosis
Kathuria P, Gordon KB, Silverberg JI
Association of psoriasis and psoriatic arthritis with osteoporosis and pathological fractures.
This study investigated whether psoriasis (Pso) and psoriatic arthritis (PsA) are associated with osteoporosis and fractures in US adults. Using records of 183,725 persons with Pso and 28,765 with PsA from the 2006-2012 National Emergency Department Sample, including 20 percent of the emergency care visits throughout the United States, it found that Pso and PsA were associated with osteopenia, osteoporosis, ankylosing spondylitis, and pathologic fractures.
AHRQ-funded; HS023011.
Citation: Kathuria P, Gordon KB, Silverberg JI .
Association of psoriasis and psoriatic arthritis with osteoporosis and pathological fractures.
J Am Acad Dermatol 2017 Mar 14;76(6):1045-53.e3. doi: 10.1016/j.jaad.2016.11.046.
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Keywords: Healthcare Cost and Utilization Project (HCUP), Osteoporosis, Injuries and Wounds, Arthritis
Franklin PD, Miozzari H, Christofilopoulos P
Important patient characteristics differ prior to total knee arthroplasty and total hip arthroplasty between Switzerland and the United States.
The researchers compared preoperative patient and clinical characteristics from two large cohorts who underwent either total knee (TKA) or hip (THA) arthroplasty, one in Switzerland, the other in the US. They found substantial differences between US and Swiss cohorts in pre-operative patient characteristics and pain levels, which has potentially important implications for cross-cultural comparison of TKA/THA outcomes.
AHRQ-funded; HS018910.
Citation: Franklin PD, Miozzari H, Christofilopoulos P .
Important patient characteristics differ prior to total knee arthroplasty and total hip arthroplasty between Switzerland and the United States.
BMC Musculoskelet Disord 2017 Jan 11;18(1):14. doi: 10.1186/s12891-016-1372-5.
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Keywords: Surgery, Pain, Patient-Centered Outcomes Research, Osteoporosis, Arthritis
Goodwin JS, Zhou J, Kuo YF
Risk of jaw osteonecrosis after intravenous bisphosphonates in cancer patients and patients without cancer.
The researchers compared the risk of jaw osteonecrosis after intravenous (IV) bisphosphonate administered to patients with cancer vs patients without cancer. During follow-up, 40 (0.42 percent) out of 9,482 patients with cancer developed probable jaw osteonecrosis compared with 8 (0.05 percent) out of 16,046 patients without cancer.
AHRQ-funded; HS022134.
Citation: Goodwin JS, Zhou J, Kuo YF .
Risk of jaw osteonecrosis after intravenous bisphosphonates in cancer patients and patients without cancer.
Mayo Clin Proc 2017 Jan;92(1):106-13. doi: 10.1016/j.mayocp.2016.09.015.
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Keywords: Cancer, Osteoporosis, Risk, Medication, Patient-Centered Outcomes Research