National Healthcare Quality and Disparities Report
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Search All Research Studies
AHRQ Research Studies Date
Topics
- Adverse Events (2)
- Blood Pressure (2)
- (-) Cardiovascular Conditions (9)
- (-) Children/Adolescents (9)
- Chronic Conditions (1)
- Critical Care (1)
- Diagnostic Safety and Quality (1)
- Emergency Department (1)
- Evidence-Based Practice (1)
- Healthcare Cost and Utilization Project (HCUP) (2)
- Heart Disease and Health (1)
- Hospitalization (1)
- Inpatient Care (1)
- Intensive Care Unit (ICU) (3)
- Patient-Centered Outcomes Research (2)
- Patient Safety (2)
- Prevention (1)
- Respiratory Conditions (1)
- Risk (1)
- Screening (1)
- U.S. Preventive Services Task Force (USPSTF) (1)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 9 of 9 Research Studies DisplayedGartlehner G, Vander Schaaf EB, Orr C
Gartlehner G, Vander Schaaf EB, Orr C, Kennedy SM, Clark R, Viswanathan M. Screening for hypertension in children and adolescents: updated evidence report and systematic review for the US Preventive Services Task Force.
This paper is an evidence update that accompanies the final recommendation from the U.S. Preventive Services Task Force (USPSTF) on screening and treatment of hypertension in childhood and adolescence. The update confirmed the previous update that the evidence is inconclusive whether the diagnostic accuracy of blood pressure measurements is adequate for screening asymptomatic children and adolescents in primary care. Forty-two studies from 43 publications were included in the final review.
AHRQ-funded; 290201500011I.
Citation: Gartlehner G, Vander Schaaf EB, Orr C .
Gartlehner G, Vander Schaaf EB, Orr C, Kennedy SM, Clark R, Viswanathan M. Screening for hypertension in children and adolescents: updated evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2020 Nov 10;324(18):1884-95. doi: 10.1001/jama.2020.11119..
Keywords: Children/Adolescents, U.S. Preventive Services Task Force (USPSTF), Blood Pressure, Screening, Evidence-Based Practice, Prevention, Cardiovascular Conditions
Sosa T, Ferris S, Frese C
Comparing two proximal measures of unrecognized clinical deterioration in children.
Critical deterioration events (CDEs) and emergency transfers (ETs) are two proximal measures to cardiopulmonary arrest, and both aim to evaluate how systems recognize and respond to clinical deterioration in children. This retrospective observational study sought to (1) characterize CDEs and ETs by timing, overlap, and intervention category, and (2) evaluate the performance of the watcher identification system and the pediatric early warning score (PEWS) to identify patients who experience these events.
AHRQ-funded; HS023827.
Citation: Sosa T, Ferris S, Frese C .
Comparing two proximal measures of unrecognized clinical deterioration in children.
J Hosp Med 2020 Nov;15(11):673-76. doi: 10.12788/jhm.3515..
Keywords: Children/Adolescents, Cardiovascular Conditions, Critical Care, Inpatient Care
Dewan M, O'Halloran A, Kleinman M
eStablish and Formalize Expert Criteria for Avoidable Resuscitation Review (SAFECARR) electronic Delphi: development of a consensus framework for classifying and reviewing cardiac arrests within the PICU.
The authors sought to develop a consensus framework to guide the process of classifying and reviewing pediatric in-hospital cardiac arrest in the PICU. A multidisciplinary group of pediatric resuscitation experts generated a consensus-based framework to classify and review pediatric in-hospital cardiac arrest in the PICU. The authors recommended that future work focus on the application of this framework and further validation of these definitions and contributing factors for in-hospital cardiac arrest both within and outside the PICU.
AHRQ-funded; HS026975.
Citation: Dewan M, O'Halloran A, Kleinman M .
eStablish and Formalize Expert Criteria for Avoidable Resuscitation Review (SAFECARR) electronic Delphi: development of a consensus framework for classifying and reviewing cardiac arrests within the PICU.
Pediatr Crit Care Med 2020 Nov;21(11):992-99. doi: 10.1097/pcc.0000000000002488..
Keywords: Children/Adolescents, Intensive Care Unit (ICU), Heart Disease and Health, Cardiovascular Conditions, Diagnostic Safety and Quality
Kaelber DC, Localio AR, Ross M
Persistent hypertension in children and adolescents: a 6-year cohort study.
The purpose of this study was to determine the natural history of pediatric hypertension. The study was conducted over a 72-month period among 165 primary care sites; blood pressure measurements from two consecutive 36-month periods were compared. Findings indicated that, in a primary care cohort, most children initially meeting criteria for hypertension or elevated blood pressure had subsequent normal blood pressure levels or did not receive recommended follow-up measurements. These results highlight the need for more nuanced initial blood pressure assessment and systems to promote follow-up of abnormal results.
AHRQ-funded; HS021645.
Citation: Kaelber DC, Localio AR, Ross M .
Persistent hypertension in children and adolescents: a 6-year cohort study.
Pediatrics 2020 Oct;146(4):Oct. doi: 10.1542/peds.2019-3778..
Keywords: Children/Adolescents, Blood Pressure, Cardiovascular Conditions, Chronic Conditions
Panupattanapong S, Stwalley DL, White AJ
Epidemiology and outcomes of granulomatosis with polyangiitis in pediatric and working-age adult populations In the United States: analysis of a large national claims database.
This retrospective cohort study examined the epidemiology and outcomes of granulomatosis with polyangiitis (GPA) in pediatric and working-age adult populations in the US. The study used data from the 2006-2014 Truven Health Analytics MarketScan Commercial Claims and Encounters Database. The incidence is rare in children, with a total of 214 (3.8%) out of 5,562 cases identified as pediatric onset. The incidence rate in children was 1.8 cases per 1 million person-years as opposed to 12.8 cases per 1 million person-years in working age adults. Children were more like to have frequent hospitalizations and severe infections including leukopenia, neutropenia, and hypogammaglobulinemia than the non-elderly adults.
AHRQ-funded; HS019455.
Citation: Panupattanapong S, Stwalley DL, White AJ .
Epidemiology and outcomes of granulomatosis with polyangiitis in pediatric and working-age adult populations In the United States: analysis of a large national claims database.
Arthritis Rheumatol 2018 Dec;70(12):2067-76. doi: 10.1002/art.40577..
Keywords: Children/Adolescents, Hospitalization, Respiratory Conditions, Cardiovascular Conditions
Gradidge EA, Bakar A, Tellez D
Safety of tracheal intubation in the presence of cardiac disease in paediatric ICUs.
In this retrospective analysis the investigators sought to evaluate the occurrence of adverse tracheal-intubation-associated events in children with cardiac disease compared to children with non-cardiac disease. The authors found that the overall incidence of adverse tracheal-intubation-associated events in cardiac patients was not different from that in non-cardiac patients. However, the presence of a cardiac diagnosis was associated with a higher occurrence of both tracheal-intubation-associated cardiac arrest and oxygen desaturation.
AHRQ-funded; HS024511.
Citation: Gradidge EA, Bakar A, Tellez D .
Safety of tracheal intubation in the presence of cardiac disease in paediatric ICUs.
Cardiol Young 2018 Jul;28(7):928-37. doi: 10.1017/s1047951118000495..
Keywords: Adverse Events, Cardiovascular Conditions, Children/Adolescents, Intensive Care Unit (ICU), Patient Safety
Silverberg JI, Kwa L, Kwa MC
Cardiovascular and cerebrovascular comorbidities of juvenile dermatomyositis in US children: an analysis of the National Inpatient Sample.
Juvenile dermatomyositis (JDM) is associated with multiple potential risk factors for cardiovascular disease, however, little is known about cardiovascular risk in JDM. This study sought to examine the association between JDM and cardiovascular risk factors and disease in US children. It concluded that there are significantly higher odds of cardiovascular and cerebrovascular comorbidities among inpatients with JDM, with adolescents, girls and racial/ethnic minorities being at highest risk.
AHRQ-funded; HS023011.
Citation: Silverberg JI, Kwa L, Kwa MC .
Cardiovascular and cerebrovascular comorbidities of juvenile dermatomyositis in US children: an analysis of the National Inpatient Sample.
Rheumatology 2018 Apr;57(4):694-702. doi: 10.1093/rheumatology/kex465..
Keywords: Cardiovascular Conditions, Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Patient-Centered Outcomes Research, Risk
Gradidge EA, Bakar A, Tellez D
Effect of location on tracheal intubation safety in cardiac disease-are cardiac ICUs safer?
In this retrospective cohort study, the investigators evaluate differences in tracheal intubation-associated events and process variances (i.e., multiple intubation attempts and oxygen desaturation) between pediatric cardiac ICUs and noncardiac PICUs in children with underlying cardiac disease. The authors found that in children with underlying cardiac disease, rates of adverse tracheal intubation-associated events were not lower in cardiac ICUs as compared to noncardiac ICUs, even after adjusting for differences in patient characteristics and care models.
AHRQ-funded; HS024511.
Citation: Gradidge EA, Bakar A, Tellez D .
Effect of location on tracheal intubation safety in cardiac disease-are cardiac ICUs safer?
Pediatr Crit Care Med 2018 Mar;19(3):218-27. doi: 10.1097/pcc.0000000000001422..
Keywords: Adverse Events, Cardiovascular Conditions, Children/Adolescents, Intensive Care Unit (ICU), Patient Safety
Michelson KA, Hudgins JD, Monuteaux MC
Cardiac arrest survival in pediatric and general emergency departments.
Understanding whether pediatric emergency departments (EDs) have higher survival than general EDs may help identify ways to improve care for all patients with out-of-hospital cardiac arrest (OHCA). Researchers sought to determine if OHCA survival differs between pediatric and general EDs. In their nationally representative sample, survival from nontraumatic OHCA was higher in pediatric EDs than general EDs. Survival did not differ in traumatic OHCA.
AHRQ-funded; HS000063.
Citation: Michelson KA, Hudgins JD, Monuteaux MC .
Cardiac arrest survival in pediatric and general emergency departments.
Pediatrics 2018 Feb;141(2). doi: 10.1542/peds.2017-2741.
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Keywords: Cardiovascular Conditions, Emergency Department, Healthcare Cost and Utilization Project (HCUP), Patient-Centered Outcomes Research, Children/Adolescents