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- Behavioral Health (1)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 8 of 8 Research Studies DisplayedAxeen S
Trends in opioid use and prescribing in Medicare, 2006-2012.
The purpose of this study was to determine characteristics and trends in opioid use, questionable use, and prescribing in Medicare. The investigators conducted a retrospective analysis of a 20 percent sample of Medicare claims data. Estimates were adjusted using multivariable regression analysis. They found that opioid utilization and prescribing were increasingly heterogeneous from 2006 to 2012.
AHRQ-funded; HS024251.
Citation: Axeen S .
Trends in opioid use and prescribing in Medicare, 2006-2012.
Health Serv Res 2018 Oct;53(5):3309-28. doi: 10.1111/1475-6773.12846..
Keywords: Medicare, Medication, Opioids, Practice Patterns
Sekhri S, Arora NS, Cottrell H
Probability of opioid prescription refilling after surgery: does initial prescription dose matter?
In this study, the investigators sought to determine the correlation between the probability of postoperative opioid prescription refills and the amount of opioid prescribed, hypothesizing that a greater initial prescription yields a lower probability of refill. The investigators concluded that the probability of refilling prescription opioids after surgery was not correlated with initial prescription strength, suggesting surgeons could prescribe smaller prescriptions without influencing refill requests.
AHRQ-funded; HS023313.
Citation: Sekhri S, Arora NS, Cottrell H .
Probability of opioid prescription refilling after surgery: does initial prescription dose matter?
Ann Surg 2018 Aug;268(2):271-76. doi: 10.1097/sla.0000000000002308..
Keywords: Medication, Opioids, Pain, Practice Patterns, Substance Abuse, Surgery
Lee JS, Parashar V, Miller JB
Opioid prescribing after curative-intent surgery: a qualitative study using the theoretical domains framework.
To identify targets for intervention, researchers performed a qualitative study of opioid prescribing after curative-intent surgery using the Theoretical Domains Framework, a well-established implementation science method for identifying factors influencing healthcare provider behavior. They concluded that key determinants of opioid prescribing behavior after curative-intent surgery include environmental and social factors. Interventions targeting these factors are likely to improve opioid prescribing in surgical oncology.
AHRQ-funded; HS023313.
Citation: Lee JS, Parashar V, Miller JB .
Opioid prescribing after curative-intent surgery: a qualitative study using the theoretical domains framework.
Ann Surg Oncol 2018 Jul;25(7):1843-51. doi: 10.1245/s10434-018-6466-x.
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Keywords: Medication, Opioids, Practice Patterns, Surgery
Axeen S, Seabury SA, Menchine M
Emergency department contribution to the prescription opioid epidemic.
The investigators used MEPS data to characterize the relative contribution of emergency departments (EDs) to national opioid prescribing, to estimate trends in opioid prescribing by site of care, and to examine whether higher-risk opioid users receive a disproportionate quantity of their opioids from ED settings. During the study period, they found that the relative contribution of EDs to the prescription opioid problem was modest and declining. They therefore recommended that further efforts to reduce the quantity of opioids prescribed focus on office-based settings.
AHRQ-funded; HS024251.
Citation: Axeen S, Seabury SA, Menchine M .
Emergency department contribution to the prescription opioid epidemic.
Ann Emerg Med 2018 Jun;71(6):659-67.e3. doi: 10.1016/j.annemergmed.2017.12.007..
Keywords: Behavioral Health, Emergency Department, Medical Expenditure Panel Survey (MEPS), Medication, Opioids, Practice Patterns, Substance Abuse
Raji MA, Kuo YF, Adhikari D
Decline in opioid prescribing after federal rescheduling of hydrocodone products.
This study examined differences in opioid prescribing by patient characteristics and variation in hydrocodone combination product (HCP) prescribing attributed to states, before and after the 2014 Drug Enforcement Administration's reclassification of HCP from schedule III to the more restrictive schedule II. It found that HCP prescribing decreased by 26 percent from June 2013 to June 2015; the rate of prescriptions for any opioid decreased by 11 percent.
AHRQ-funded; HS022134.
Citation: Raji MA, Kuo YF, Adhikari D .
Decline in opioid prescribing after federal rescheduling of hydrocodone products.
Pharmacoepidemiol Drug Saf 2018 May;27(5):513-19. doi: 10.1002/pds.4376.
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Keywords: Policy, Opioids, Practice Patterns, Policy
Kuo YF, Raji MA, Liaw V
Opioid prescriptions in older Medicare beneficiaries after the 2014 federal rescheduling of hydrocodone products.
The authors sought to examine how an October 2014 Drug Enforcement Administration policy reclassified hydrocodone product from schedule III to II has affected older adults. They found that the 2014 change in hydrocodone from schedule III to schedule II was associated with modest decreases in rates of opioid use in the elderly. They also found an unexpected increase in opioid-related hospitalizations without documented opioid prescriptions, which may represent an increase in illegal use.
AHRQ-funded; HS022134.
Citation: Kuo YF, Raji MA, Liaw V .
Opioid prescriptions in older Medicare beneficiaries after the 2014 federal rescheduling of hydrocodone products.
J Am Geriatr Soc 2018 May;66(5):945-53. doi: 10.1111/jgs.15332.
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Keywords: Elderly, Medicare, Opioids, Policy, Practice Patterns
Howard R, Waljee J, Brummett C
Reduction in opioid prescribing through evidence-based prescribing guidelines.
The authors evaluated the effect of evidence-based postoperative prescribing guidelines in an effort to reduce overprescribing. The post-intervention group received opioid prescriptions for reduced dosages compared to the pre-intervention group. In the post-intervention group, 2.5% requested refills compared with 4.1% in the pre-intervention group. The authors indicated that this work will be used as a template for statewide practice transformation, which may serve as a platform for other states.
AHRQ-funded; HS023313.
Citation: Howard R, Waljee J, Brummett C .
Reduction in opioid prescribing through evidence-based prescribing guidelines.
JAMA Surg 2018 Mar;153(3):285-87. doi: 10.1001/jamasurg.2017.4436.
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Keywords: Evidence-Based Practice, Guidelines, Opioids, Practice Patterns, Surgery
Kim HS, McCarthy DM, Hoppe JA
Emergency department provider perspectives on benzodiazepine-opioid coprescribing: a qualitative study.
This study examined attitudes of emergency department residents, attending physicians, and pharmacists from three hospitals on coprescribing benzodiazepines and opioids. There is mounting evidence that this increases overdose risk. Focus groups were conducted using semistructured interviews which were audio-recorded and transcribed. Participants were reluctant to admit coprescribing and said when they did that specific discharge instructions were provided. The decision was also influenced by a provider’s belief in the efficacy of combination therapy as well as self-imposed pressure to escalate care or avoid hospital admission. They did not like the idea of using computerized alerts, but were support of pharmacist-assisted interventions.
AHRQ-funded; HS023011; HS000078.
Citation: Kim HS, McCarthy DM, Hoppe JA .
Emergency department provider perspectives on benzodiazepine-opioid coprescribing: a qualitative study.
Acad Emerg Med 2018 Jan;25(1):15-24. doi: 10.1111/acem.13273..
Keywords: Emergency Department, Guidelines, Medication, Opioids, Practice Patterns, Provider: Clinician, Provider: Pharmacist, Provider: Physician