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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 1 of 1 Research Studies DisplayedNewman TB, Wu YW, Kuzniewicz MW
Childhood seizures after phototherapy.
A recent Danish study found an increased risk of childhood epilepsy only in boys after phototherapy; researchers investigated this association in a Kaiser Permanente Northern California cohort of infants born after at least 35 weeks' gestation in 1995-2011. The mean follow-up period was 8.1 years. Primary outcome was at least 1 encounter with a seizure diagnosis plus at least 1 prescription for an antiepileptic drug. Results indicated that boys were at higher risk of seizures overall, and had a higher adjusted hazard ratio for phototherapy than girls, although effect modification by sex was not statistically significant. The researchers conclude that infant phototherapy is associated with a small increased risk of childhood seizures, and the risk is more significant in boys.
AHRQ-funded; HS020618.
Citation: Newman TB, Wu YW, Kuzniewicz MW .
Childhood seizures after phototherapy.
Pediatrics 2018 Oct;142(4):pii: e20180648. doi: 10.1542/peds.2018-0648..
Keywords: Adverse Events, Children/Adolescents, Neurological Disorders, Risk