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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 2 of 2 Research Studies DisplayedGaither JR, Goulet JL, Becker WC
The effect of substance use disorders on the association between guideline-concordant long-term opioid therapy and all-cause mortality.
The objective of this study was to determine whether the presence of a substance use disorder (SUD) modifies the association between guideline-concordant care and 1-year all-cause mortality among patients receiving long-term opioid therapy (LtOT) for pain. It found that for clinicians prescribing LtOT to patients with untreated SUDs, engaging patients with psychotherapeutic and SUD treatment services may reduce mortality.
AHRQ-funded; U19 HS021112.
Citation: Gaither JR, Goulet JL, Becker WC .
The effect of substance use disorders on the association between guideline-concordant long-term opioid therapy and all-cause mortality.
J Addict Med 2016 Nov/Dec;10(6):418-28. doi: 10.1097/adm.0000000000000255.
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Keywords: Care Management, Medication, Mortality, Substance Abuse, Opioids, Patient-Centered Outcomes Research
Mukherjee JT, Beshansky JR, Ruthazer R
In-hospital measurement of left ventricular ejection fraction and one-year outcomes in acute coronary syndromes: results from the IMMEDIATE Trial.
The relationships between reduced left ventricular ejection fraction (LVEF) measured during index acute coronary syndrome (ACS) hospitalization and mortality and heart failure (HF) within 1 year are not well-defined. The researchers performed a retrospective analysis of 445 patients who had LVEF measured by left ventriculography or echocardiogram during hospitalization. They found that among patients with ACS, lower in-hospital LVEF is associated with increased 1-year mortality or hospitalization for HF.
AHRQ-funded; HS000060.
Citation: Mukherjee JT, Beshansky JR, Ruthazer R .
In-hospital measurement of left ventricular ejection fraction and one-year outcomes in acute coronary syndromes: results from the IMMEDIATE Trial.
Cardiovasc Ultrasound 2016 Aug 3;14(1):29. doi: 10.1186/s12947-016-0068-1.
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Keywords: Cardiovascular Conditions, Care Management, Heart Disease and Health, Mortality, Outcomes