National Healthcare Quality and Disparities Report
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Topics
- Antibiotics (1)
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- (-) Women (14)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 14 of 14 Research Studies DisplayedTeixeira da Silva D, Makeneni S, Wall H
Measuring quality STI care among adolescent female primary care patients in Philadelphia.
The purpose of this study was to develop and apply a cross-setting, sexually transmitted infection (STI) Care Continuum to improve STI care quality, to assess adherence to guideline-recommended care, and to standardize progress measurement toward National Strategic goals. Review of the CDC STI treatment guidelines identified seven distinct steps of care for gonorrhea, chlamydia, and syphilis; researchers used Youth Risk Behavior Surveillance Survey data to estimate step 1, and electronic health record data for steps 2, 3, 4, 6 and 7. The researchers concluded that local application of an STI Care Continuum identified STI testing, retesting, and HIV testing as areas for improvement. Similar methods may be applied to target resources, standardize data collection and reporting, and improve STI care quality.
AHRQ-funded; HS026116.
Citation: Teixeira da Silva D, Makeneni S, Wall H .
Measuring quality STI care among adolescent female primary care patients in Philadelphia.
Sex Transm Infect 2023 Jun; 99(4):272-75. doi: 10.1136/sextrans-2022-055623..
Keywords: Children/Adolescents, Sexual Health, Infectious Diseases, Primary Care, Women, Human Immunodeficiency Virus (HIV), Quality Measures, Quality of Care
Glenn BA, Nonzee NJ, Tieu L
Human papillomavirus (HPV) vaccination in the transition between adolescence and adulthood.
This study looked at the barriers to human papillomavirus (HPV) vaccination among young adults receiving care at the student health center of a large public university. The authors conducted semi-structured interviews (n=27) and four focus groups with undergraduate and graduate students (n=18) and semi-structured interviews with 6 health care providers. The interviews and focus groups explored perceived risk of HPV infection, benefits of the HPV vaccine, and motivations for and barriers to HPV vaccination. Many students cited their parents’ views and recommendations from their medical providers as influential on their decision-making process. Cervical cancer prevention was considered the main benefit of the HPV vaccine and sexual activity was a risk factor for HPV infection. Students often lacked knowledge about the vaccine’s benefit for males. Safety and side effects of the vaccine perceived as new were also cited. Providers’ vaccine recommendations were impacted by health system factors including clinical infrastructure, office visit priorities, and processes for recommending and documentation vaccination. Providers suggested various promotion strategies including improving the timing and messaging of outreach efforts on campus and bolstering clinical infrastructure.
AHRQ-funded; HS000046.
Citation: Glenn BA, Nonzee NJ, Tieu L .
Human papillomavirus (HPV) vaccination in the transition between adolescence and adulthood.
Vaccine 2021 Jun 8;39(25):3435-44. doi: 10.1016/j.vaccine.2021.04.019..
Keywords: Young Adults, Sexual Health, Infectious Diseases, Vaccination, Prevention, Cancer: Cervical Cancer, Cancer, Women
Van Gerwen OT, Tamhane A, Westfall AO
Prevalence of and factors associated with genital and extragenital chlamydia and gonorrhea among transgender women in HIV care in the United States, 2005 to 2016.
This retrospective cohort analysis included transgender women living with HIV enrolled in the US Centers for AIDS Research Network of Integrated Clinical Systems cohort between January 2005 and December 2016 with chlamydia or gonorrhea testing performed in HIV clinic. The investigators concluded that among transgender women living with HIV, testing rates for chlamydia and gonorrhea were inadequate, particularly at extragenital sites where most infections occur.
AHRQ-funded; HS013852.
Citation: Van Gerwen OT, Tamhane A, Westfall AO .
Prevalence of and factors associated with genital and extragenital chlamydia and gonorrhea among transgender women in HIV care in the United States, 2005 to 2016.
Sex Transm Dis 2021 Jun 1;48(6):410-16. doi: 10.1097/olq.0000000000001335.
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Keywords: Human Immunodeficiency Virus (HIV), Sexual Health, Infectious Diseases, Women
Barrero-Castillero A, Beam KS, Bernardini LB
COVID-19: neonatal-perinatal perspectives.
This review provides a comprehensive overview of neonatal-perinatal perspectives of COVID-19, ranging from the basic science of infection and recommendations for care of pregnant women and neonates to important psychosocial, ethical, and racial/ethnic topics emerging as a result of both the pandemic and the response of the healthcare community to the care of infected individuals.
AHRQ-funded; HS000063.
Citation: Barrero-Castillero A, Beam KS, Bernardini LB .
COVID-19: neonatal-perinatal perspectives.
J Perinatol 2021 May;41(5):940-51. doi: 10.1038/s41372-020-00874-x..
Keywords: COVID-19, Newborns/Infants, Infectious Diseases, Pregnancy, Women
Asti L, Hopley C, Avelis C
The potential clinical and economic value of a human papillomavirus primary screening test that additionally identifies genotypes 31, 45, 51, and 52 individually.
This study looked at the potential clinical and economic value of a human papillomavirus (HPV) primary screening test that additionally identified genotypes 31,45,51, and 52 along with genotypes 16 and 18. The authors developed a Markov model of the HPV disease course and evaluated the clinical and economic value of HPV primary screening with Onclarity. Currently HPV primary screening results in 25,194 invasive procedures and 48 invasive cervical cancer (ICC) cases per 100,000 women. Screening with extended genotyping and later screening women with certain genotypes averted 903 to 3163 invasive procedures and results in 0 to 3 more ICC cases compared with current primary screening tests. Extended genotyping was cost effective when costing $75 and cost saving when costing $43. When the probabilities of disease progression increased 2-4 times, it was not cost-effective because it resulted in more ICC cases and accrued fewer quality-adjusted life-years.
AHRQ-funded; HS023317.
Citation: Asti L, Hopley C, Avelis C .
The potential clinical and economic value of a human papillomavirus primary screening test that additionally identifies genotypes 31, 45, 51, and 52 individually.
Sex Transm Dis 2021 May;48(5):370-80. doi: 10.1097/olq.0000000000001327.
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Keywords: Sexual Health, Infectious Diseases, Screening, Diagnostic Safety and Quality, Genetics, Cancer: Cervical Cancer, Cancer, Women
Rodriguez PJ, Roberts DA, Meisner J
Cost-effectiveness of dual maternal HIV and syphilis testing strategies in high and low HIV prevalence countries: a modelling study.
Dual HIV and syphilis testing might help to prevent mother-to-child transmission (MTCT) of HIV and syphilis through increased case detection and treatment. In this study, the investigators aimed to model and assess the cost-effectiveness of dual testing during antenatal care in four countries with varying HIV and syphilis prevalence. The authors concluded that incorporating dual rapid diagnostic tests in antenatal care could be cost-saving across countries with varying HIV prevalence.
AHRQ-funded; HS013853.
Citation: Rodriguez PJ, Roberts DA, Meisner J .
Cost-effectiveness of dual maternal HIV and syphilis testing strategies in high and low HIV prevalence countries: a modelling study.
Lancet Glob Health 2021 Jan;9(1):e61-e71. doi: 10.1016/s2214-109x(20)30395-8..
Keywords: Human Immunodeficiency Virus (HIV), Infectious Diseases, Prevention, Pregnancy, Women, Diagnostic Safety and Quality, Healthcare Costs
Schafer R, Phillippi JC
Group B streptococcal bacteriuria in pregnancy: an evidence-based, patient-centered approach to care.
Screening and management of group B streptococcus (GBS) bacteriuria in pregnancy aims to reduce the incidence of pyelonephritis and GBS-related neonatal morbidity and mortality. This article used a case study approach to discuss evidence-based, patient-centered care for group B streptococcal bacteriuria in pregnancy as well as ethical incorporation of individual patient preferences and values.
AHRQ-funded; HS024733.
Citation: Schafer R, Phillippi JC .
Group B streptococcal bacteriuria in pregnancy: an evidence-based, patient-centered approach to care.
J Midwifery Womens Health 2020 May;65(3):376-81. doi: 10.1111/jmwh.13085..
Keywords: Infectious Diseases, Pregnancy, Women, Patient-Centered Healthcare, Evidence-Based Practice, Newborns/Infants, Sepsis, Case Study
Sun CJ, Anderson KM, Kuhn T
A sexual health promotion app for transgender women (Trans Women Connected): development and usability study.
HIV severely impacts the transgender communities in the United States, and transgender women have the highest HIV incidence rates among any identified risk group. Guided by formative research with transgender women and by an expert advisory panel of transgender women, the investigators designed a prototype mobile app to promote HIV prevention among transgender women. This study aimed to develop and test the usability and acceptability of the prototype Trans Women Connected mobile app.
AHRQ-funded; HS022981.
Citation: Sun CJ, Anderson KM, Kuhn T .
A sexual health promotion app for transgender women (Trans Women Connected): development and usability study.
JMIR Mhealth Uhealth 2020 May 12;8(5):e15888. doi: 10.2196/15888..
Keywords: Human Immunodeficiency Virus (HIV), Health Promotion, Sexual Health, Infectious Diseases, Prevention, Women
Bartsch SM, Asti L, Stokes-Cawley OJ
The potential economic value of a Zika vaccine for a woman of childbearing age.
The authors mapped the Zika vaccine and vaccination characteristic thresholds at which vaccination becomes cost effective, highly cost effective, and cost saving. They developed a Markov model to simulate a woman of childbearing age to follow the potential risk and clinical course of a Zika infection. They found that, in some cases, the vaccine was cost effective when the risk was as low as 0.015%, the cost was as high as $7,500, the efficacy was as low as 25%, and the duration of protection was 1 year. They concluded that the thresholds at which vaccination becomes cost effective and cost saving can provide targets for Zika vaccine development and implementation.
AHRQ-funded; HS023317.
Citation: Bartsch SM, Asti L, Stokes-Cawley OJ .
The potential economic value of a Zika vaccine for a woman of childbearing age.
Am J Prev Med 2020 Mar;58(3):370-77. doi: 10.1016/j.amepre.2019.10.023..
Keywords: Vaccination, Women, Infectious Diseases, Public Health, Healthcare Costs, Prevention
Muzny CA, Tamhane AR, Eaton EF
Incidence and predictors of reinfection with trichomoniasis based on nucleic acid amplification testing results in HIV-infected patients.
Trichomonas vaginalis infection contributes to HIV transmission. The purpose of this retrospective cohort study was to determine the incidence and predictors of T. vaginalis reinfection among HIV-infected women in Birmingham, Alabama. The investigators indicated that T. vaginalis reinfection was high among HIV-infected women in the sample, necessitating enhanced disease control efforts in this high-risk population.
AHRQ-funded; HS023009.
Citation: Muzny CA, Tamhane AR, Eaton EF .
Incidence and predictors of reinfection with trichomoniasis based on nucleic acid amplification testing results in HIV-infected patients.
Trichomonas vaginalis infection contributes to HIV transmission. The purpose of this retrospective cohort study was to determine the incidence and predictors of T. vaginalis reinfection among HIV-infected women in Birmingham, Alabama. The investigators indicated that T. vaginalis reinfection was high among HIV-infected women in the sample, necessitating enhanced disease control efforts in this high-risk population..
Keywords: Human Immunodeficiency Virus (HIV), Infectious Diseases, Women
Wynn A, Ramogola-Masire D, Gaolebale P
Prevalence and treatment outcomes of routine Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis testing during antenatal care, Gaborone, Botswana.
AHRQ-funded; HS000046.
Citation: Wynn A, Ramogola-Masire D, Gaolebale P .
Prevalence and treatment outcomes of routine Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis testing during antenatal care, Gaborone, Botswana.
Sex Transm Infect 2018 May;94(3):230-35. doi: 10.1136/sextrans-2017-053134..
Keywords: Antibiotics, Human Immunodeficiency Virus (HIV), Infectious Diseases, Pregnancy, Women
Silver MI, Rositch AF, Phelan-Emrick DF
Uptake of HPV testing and extended cervical cancer screening intervals following cytology alone and Pap/HPV cotesting in women aged 30-65 years.
To evaluate the adoption of HPV testing and recommended extended cervical cancer screening intervals in clinical practice, researchers described yearly uptake of Pap/HPV cotesting and estimated length of time between normal screens by patient characteristics. They concluded that increased screening intervals were observed only among cotested women, while those screened by cytology alone continued to be screened almost annually.
AHRQ-funded; HS022199.
Citation: Silver MI, Rositch AF, Phelan-Emrick DF .
Uptake of HPV testing and extended cervical cancer screening intervals following cytology alone and Pap/HPV cotesting in women aged 30-65 years.
Cancer Causes Control 2018 Jan;29(1):43-50. doi: 10.1007/s10552-017-0976-x.
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Keywords: Cancer, Infectious Diseases, Prevention, Screening, Women
Offorjebe OA, Wynn A, Moshashane N
Partner notification and treatment for sexually transmitted infections among pregnant women in Gaborone, Botswana.
This paper describes a prospective cohort study which was conducted among 300 pregnant women presenting to the antenatal clinic at Princess Marina Hospital in Gaborone, Botswana who enrolled in an STI screening study. The authors specifically examine partner notification and treatment. They conclude that their findings suggest that pregnant women are willing to utilize patient-based partner notification, but actual partner treatment might be lower than intended.
AHRQ-funded; HS000046.
Citation: Offorjebe OA, Wynn A, Moshashane N .
Partner notification and treatment for sexually transmitted infections among pregnant women in Gaborone, Botswana.
Int J STD AIDS 2017 Oct;28(12):1184-89. doi: 10.1177/0956462417692455..
Keywords: Infectious Diseases, Pregnancy, Screening, Women
Khan MJ, Massad LS, Kinney W
A common clinical dilemma: Management of abnormal vaginal cytology and human papillomavirus test results.
The researchers reviewed the literature on vaginal cytology and high-risk HPV testing and developed guidance for the management of abnormal vaginal screening tests. Since vaginal cancer is rare, the authors suggested that asymptomatic low-risk women not be screened. They further proposed an algorithm based on expert opinion for managing women with abnormal vaginal test results.
AHRQ-funded; HS023009.
Citation: Khan MJ, Massad LS, Kinney W .
A common clinical dilemma: Management of abnormal vaginal cytology and human papillomavirus test results.
J Low Genit Tract Dis 2016 Apr;20(2):119-25. doi: 10.1097/lgt.0000000000000185.
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Keywords: Cancer, Care Management, Infectious Diseases, Sexual Health, Women