159. Treatment Recommendations: Medications-Relative Effectiveness (Continued)
Treating Tobacco Use and Dependence: 2008 Update
Text version of slide presentation.
Meta-analysis (2008): Effectiveness and abstinence rates of medications relative to the nicotine patch (n = 86 studies).
| Medication | Number of arms | Estimated odds ratio (95% C. I.) |
|---|---|---|
| Nicotine Patch (reference group) | 32 | 1.0 |
| Combination therapies | ||
| Patch (long-term; > 14 weeks) + NRT (gum or spray) | 3 | 1.9 (1.3, 2.7) |
| Patch + Bupropion SR | 3 | 1.3 (1.0, 1.8) |
| Patch + Nortriptyline | 2 | 0.9 (0.6, 1.4) |
| Patch + Inhaler | 2 | 1.1 (0.7, 1.9) |
| Second-generation antidepressants & Patch | 3 | 1.0 (0.6, 1.7) |
| Medications not shown to be effective | ||
| Selective Serotonin Reuptake Inhibitors (SSRIs) | 3 | 0.5 (0.4, 0.7) |
| Naltrexone | 2 | 0.3 (0.1, 0.6) |
