16. Strength of Evidence for Recommendations
Treating Tobacco Use and Dependence: 2008 Update Overview
|Strength of Evidence = A
|Multiple well-designed randomized clinical trials, directly relevant to the recommendation, yielded a consistent pattern of findings.
|Strength of Evidence = B
|Some evidence from randomized clinical trials supported the recommendation, but the scientific support was not optimal. For instance, few randomized trials existed, the trials that did exist were somewhat inconsistent, or the trials were not directly relevant to the recommendation.
|Strength of Evidence = C
|Reserved for important clinical situations where the panel achieved consensus on the recommendation in the absence of relevant randomized controlled trials.