152. Treatment Recommendations: Medications-Clonidine (Continued)

Treating Tobacco Use and Dependence: 2008 Update

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Oral—Prescription only.

Transdermal—Prescription only.

Prescribing instructions

Initiate—Initiate clonidine shortly before (up to 3 days), or on, the quit date.

Dosing information—If the patient is using transdermal clonidine, at the start of each week, he or she should place a new patch on a relatively hairless location between the neck and waist. Users should not discontinue clonidine therapy abruptly.


Oral—.1 mg box of 60 = $13.00 (daily dosage determines how long supply lasts)

Transdermal—4 pack-TTS = $106.00

a. Cost data were established by averaging the retail price of the medication at national chain pharmacies in Atlanta, GA, Los Angeles, CA, Milwaukee, WI, Sunnyside, NY and listed on-line during January 2008 and may not reflect discounts available to health plans and others.

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Page last reviewed October 2014
Page originally created September 2012
Internet Citation: 152. Treatment Recommendations: Medications-Clonidine (Continued). Content last reviewed October 2014. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/professionals/clinicians-providers/guidelines-recommendations/tobacco/clinicians/presentations/2008update-full/slide152.html