National Healthcare Quality and Disparities Report
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
3901 to 3925 of 12214 Research Studies DisplayedKubi B, Enumah ZO, Lee KT
Theory-based development of an implementation intervention using community health workers to increase palliative care use.
This study used the Behavior Change Wheel and Theoretical Domains Framework models to help design an implementation intervention using community health workers (CHWs) to increase palliative care use in African American communities. There were two phases to the study. In Phase 1, focus group sessions were conducted to identify barriers and facilitators of palliative care use. Phase 2 consisted of a stakeholder meeting to select intervention content and prioritize modes of delivery after applying the framework. There were 15 stakeholders total that participated in the study. Interventions identified were designed to improve patient capability and motivation, physician capability and motivation, and increase patient opportunities to use palliative care services. The strategies were all facilitated by CHWs and included creation and dissemination of brochures, empowerment and activation of patients to initiate goals-of-care discussions, outreach to community churches, and expanding patient social support.
AHRQ-funded; HS024736.
Citation: Kubi B, Enumah ZO, Lee KT .
Theory-based development of an implementation intervention using community health workers to increase palliative care use.
J Pain Symptom Manage 2020 Jul;60(1):10-19. doi: 10.1016/j.jpainsymman.2020.02.009..
Keywords: Community-Based Practice, Palliative Care, Healthcare Utilization, Racial and Ethnic Minorities, Implementation, Disparities, Healthcare Delivery
Papaleontiou M, Haymart MR
Thyroid nodules and cancer during pregnancy, post-partum and preconception planning: addressing the uncertainties and challenges.
This article describes the challenges of treating thyroid nodules and thyroid cancer during pregnancy, in the postpartum period, and during preconception planning. The benefits and risk of treatment are discussed based on current knowledge and controversies surrounding management during pregnancy.
AHRQ-funded; HS024512.
Citation: Papaleontiou M, Haymart MR .
Thyroid nodules and cancer during pregnancy, post-partum and preconception planning: addressing the uncertainties and challenges.
Best Pract Res Clin Endocrinol Metab 2020 Jul;34(4):101363. doi: 10.1016/j.beem.2019.101363..
Keywords: Cancer, Pregnancy, Maternal Care, Women
Gerber DE, Hamann HA, Chavez C
Tracking the nonenrolled: lung cancer screening patterns among individuals not accrued to a clinical trial.
Researchers investigated lung cancer screening patterns among individuals eligible for, but not enrolled in, a screening trial. They found that, in their single-center study, demographic factors did not predict for participation in a lung cancer screening trial; lung cancer screening adherence rates were substantially lower for those not enrolled in a screening trial, especially for those who could not be contacted. The researchers conclude that these findings may inform the broader implementation of screening programs.
AHRQ-funded; HS022418.
Citation: Gerber DE, Hamann HA, Chavez C .
Tracking the nonenrolled: lung cancer screening patterns among individuals not accrued to a clinical trial.
Clin Lung Cancer 2020 Jul;21(4):326-32. doi: 10.1016/j.cllc.2020.02.010..
Keywords: Cancer: Lung Cancer, Cancer, Screening
Dombrowski M, Illuzzi JL, Reddy UM
Trial of labor after two prior cesarean deliveries: patient and hospital characteristics and birth outcomes.
This study’s goal was to examine utilization, success rate, and maternal and neonatal outcomes of trial of labor among women with two prior cesarean deliveries. Linked hospital discharge and birth certificate data were used for a retrospective analyses of a cohort of women in California with nonanomalous, term, singleton live births, two prior cesarean deliveries, and no clear contraindications for trial of labor. Findings showed that, among women with two prior cesarean deliveries, trial of labor was rarely attempted and was successful in 39.4% of attempts. Trial of labor in this population was associated with a modest increase in severe neonatal morbidity.
AHRQ-funded; HS023801.
Citation: Dombrowski M, Illuzzi JL, Reddy UM .
Trial of labor after two prior cesarean deliveries: patient and hospital characteristics and birth outcomes.
Obstet Gynecol 2020 Jul;136(1):109-17. doi: 10.1097/aog.0000000000003845.
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Keywords: Labor and Delivery, Pregnancy, Women, Maternal Care, Outcomes
Varley AL, Kripalani S, Spain T
Understanding factors influencing quality improvement capacity among ambulatory care practices across the MidSouth region: an exploratory qualitative study.
Success in choosing and implementing quality metrics, necessary in a value-based care model, depends on quality improvement (QI) capacity-the shared knowledge, understanding, and commitment to continuous improvement. In this study, the investigators set out to explore factors influencing QI capacity among ambulatory care practices in the MidSouth Practice Transformation Network. Their findings provide insight into factors influencing the adoption and implementation of QI metrics across a diverse group of ambulatory care practices.
AHRQ-funded; HS013852.
Citation: Varley AL, Kripalani S, Spain T .
Understanding factors influencing quality improvement capacity among ambulatory care practices across the MidSouth region: an exploratory qualitative study.
Qual Manag Health Care 2020 Jul/Sep;29(3):136-41. doi: 10.1097/qmh.0000000000000255..
Keywords: Quality Improvement, Quality of Care, Ambulatory Care and Surgery, Practice Improvement
Atkins M, Castro I, Sharifi M
Unmet social needs and adherence to pediatric weight management interventions: Massachusetts, 2017-2019.
This study examined the effects of housing insecurity and unmet social needs on adherence to pediatric weight management intervention (PWMI) programs. The authors used data from children enrolled in a 2017-2019 comparative effectiveness trial for 2 high-intensive PWMIs in Massachusetts. Families with housing security had higher contact hours with the program than families without. Children with 3 to 4 unmet social needs (parental stress, parental depression, food insecurity, and housing insecurity) also attended less hours of the program than those without.
AHRQ-funded; HS024332.
Citation: Atkins M, Castro I, Sharifi M .
Unmet social needs and adherence to pediatric weight management interventions: Massachusetts, 2017-2019.
Am J Public Health 2020 Jul;110(S2):S251-s57. doi: 10.2105/ajph.2020.305772..
Keywords: Children/Adolescents, Obesity: Weight Management, Obesity, Patient Adherence/Compliance, Social Determinants of Health, Family Health and History
Fiori KP, Heller CG, Rehm CD
Unmet social needs and no-show visits in primary care in a US Northeastern urban health system, 2018-2019.
This study used results from a 10-item social needs screener conducted across 19 primary care practices in Bronx County, New York to determine reasons for no-show appointments between April 2018 and July 2019. They examined the association between unmet needs and a 2-year history of missed appointments from 41,637 patients. Overall, the no-show appointment rate was 26.6%. Patients with 1 or more unmet social needs had a significantly higher no-show proportion (31.5%) than those without (26.3%). The strongest association with no-shows was with transportation problems.
AHRQ-funded; HS026396.
Citation: Fiori KP, Heller CG, Rehm CD .
Unmet social needs and no-show visits in primary care in a US Northeastern urban health system, 2018-2019.
Am J Public Health 2020 Jul;110(S2):S242-s50. doi: 10.2105/ajph.2020.305717..
Keywords: Urban Health, Primary Care, Access to Care, Social Determinants of Health
Utter GH, Dhillon TS, Danielsen BH
Use of statewide administrative data to assess clinical outcomes: a retrospective cohort study of therapeutic anticoagulation for isolated calf vein thrombosis.
Single-center comparative effectiveness studies evaluating outcomes that can occur posthospitalization may become biased if outcomes diagnosed at other facilities are not ascertained. Administrative datasets that link patients' records across facilities may improve outcome ascertainment. The purpose of this study was to determine whether use of linked administrative data significantly augmented thromboembolic outcome ascertainment. The investigators concluded that use of linked hospital administrative data augmented detection of outcomes but imperfect linkage, nonspecific diagnoses, and documentation/coding errors introduced uncertainty regarding the accuracy of outcome ascertainment.
AHRQ-funded; HS022236.
Citation: Utter GH, Dhillon TS, Danielsen BH .
Use of statewide administrative data to assess clinical outcomes: a retrospective cohort study of therapeutic anticoagulation for isolated calf vein thrombosis.
Med Care 2020 Jul;58(7):658-62. doi: 10.1097/mlr.0000000000001347.
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Keywords: Blood Clots, Blood Thinners, Medication, Research Methodologies, Patient-Centered Outcomes Research
Franc BL, Thombley R, Luo Y
Using diagnosis codes in claims data to identify cohorts of breast cancer patients following initial treatment.
This article describes how researchers trying to study patterns of care and medical service utilization can use diagnosis codes to help identify patients who had undergone initial breast cancer treatment during the first 5 years after treatment for the primary cancer. The authors used claims data of 51,278 newly diagnosed breast cancer (BC) patients from the BC subset of the 2000-2014 SEER-Medicare linked database. From that database they determined the fraction of BC patients who could be identified using BC-specific does 174.x and v10.3 during the year of diagnosis/treatment and during each of the following 5 years after treatment. They then developed a list of diagnosis codes that were found more often in claims from BC patients than in claims of a cohort of patients without a BC diagnosis. They were able to identify BC patients as belonging to 5 different subgroups. In any single year 72.8-99.1% of BC patients had a claim with a174.x diagnosis code. Another 0-11% of BC patients had a v10.3 code. From their findings they concluded that BC patients can be robustly identified within claims databases.
AHRQ-funded; HS024936.
Citation: Franc BL, Thombley R, Luo Y .
Using diagnosis codes in claims data to identify cohorts of breast cancer patients following initial treatment.
Breast J 2020 Jul;26(7):1472-74. doi: 10.1111/tbj.13758..
Keywords: Cancer: Breast Cancer, Cancer, Diagnostic Safety and Quality, Women, Research Methodologies
Ferguson MC, Morgan MJ, O'Shea KJ
Using simulation modeling to guide the design of the Girl Scouts Fierce & Fit Program.
The goal of this study was to see if computational modeling would help to revise the design of the Girl Scouts Fierce & Fit Program. The Girl Scouts of Central Maryland worked with the researchers to develop a computational simulation model representing the 250 adolescent girls who were participating in the program to determine how their diets and physical activity affected their BMI and subsequent outcomes, including costs. As a result, the program changed from 6 weeks meeting twice a week with 5 minutes of physical activity each session to meeting 12 weeks with 30 minutes of physical activity each session. Cost savings were estimated at an additional $84,828 in lifetime direct medical costs, $81,365 in lifetime productivity losses, and 7.85 quality-adjusted life-years.
AHRQ-funded; HS023317.
Citation: Ferguson MC, Morgan MJ, O'Shea KJ .
Using simulation modeling to guide the design of the Girl Scouts Fierce & Fit Program.
Using simulation modeling to guide the design of the Girl Scouts Fierce & Fit Program.
Obesity 2020 Jul;28(7):1317-24. doi: 10.1002/oby.22827..
Obesity 2020 Jul;28(7):1317-24. doi: 10.1002/oby.22827..
Keywords: Children/Adolescents, Obesity: Weight Management, Obesity, Lifestyle Changes
Homco J, Carabin H, Nagykaldi Z
Validity of medical record abstraction and electronic health record-generated reports to assess performance on cardiovascular quality measures in primary care.
The purpose of this study was to compare observed performance scores measured using 2 imperfect reference standard data sources with misclassification-adjusted performance scores obtained using bayesian latent class analysis. Using aspirin, blood pressure, and smoking performance data from the Healthy Hearts for Oklahoma Project, researchers found that extracting information for the same individuals using different data sources generated different performance score estimates. Recommendations included further research to identify the sources of these differences.
AHRQ-funded; HS023919.
Citation: Homco J, Carabin H, Nagykaldi Z .
Validity of medical record abstraction and electronic health record-generated reports to assess performance on cardiovascular quality measures in primary care.
JAMA Netw Open 2020 Jul;3(7):e209411. doi: 10.1001/jamanetworkopen.2020.9411..
Keywords: Electronic Health Records (EHRs), Health Information Technology (HIT), Cardiovascular Conditions, Quality Measures, Quality of Care, Primary Care, Provider Performance, Evidence-Based Practice
Nanji KC, Merry AF, Shaikh SD KC, Merry AF, Shaikh SD
Global PRoMiSe (Perioperative Recommendations for Medication Safety): protocol for a mixed-methods study.
Medication errors (MEs), which occur commonly in the perioperative period, have the potential to cause patient harm or death. Many published recommendations exist for preventing perioperative MEs; however, many of these recommendations conflict and are often not applicable to middle-income and low-income countries. The goal of this study was to develop and disseminate consensus-based recommendations for perioperative medication safety that were tailored to country income level.
AHRQ-funded; HS024764.
Citation: Nanji KC, Merry AF, Shaikh SD KC, Merry AF, Shaikh SD .
Global PRoMiSe (Perioperative Recommendations for Medication Safety): protocol for a mixed-methods study.
BMJ Open 2020 Jun 30;10(6):e038313. doi: 10.1136/bmjopen-2020-038313..
Keywords: Medication, Medication: Safety, Patient Safety, Adverse Drug Events (ADE), Adverse Events, Medical Errors
Brach C, Borsky A
AHRQ Author: Brach C, Borsky A
How the U.S. Agency for Healthcare Research and Quality promotes health literate health care.
This AHRQ-authored study traces the history of the AHRQ Health Literacy Action Plan to promote health literate health care delivery systems. This Plan has been developed and implemented for almost 15 years and serves as the framework for AHRQ’s efforts to 1) Develop measures; 2) Improve the evidence base and create implementation tools; 3) Create and support change; 4) Disseminate and transfer knowledge and tools; and 5) Practice what we preach.
AHRQ-authored.
Citation: Brach C, Borsky A .
How the U.S. Agency for Healthcare Research and Quality promotes health literate health care.
Stud Health Technol Inform 2020 Jun 25;269:313-23. doi: 10.3233/shti200046..
Keywords: Health Literacy, Healthcare Delivery, Health Services Research (HSR), Implementation
Abreo A, Wu P, Donovan BM
Infant respiratory syncytial virus bronchiolitis and subsequent risk of pneumonia, otitis media, and antibiotic utilization.
This study looked at infant respiratory syncytial virus (RSV) bronchiolitis and its association with increased odds of pneumonia, otitis media, and antibiotic utilization in infants 7-12 months. The data suggested the potential value of future RSV vaccination programs on subsequent respiratory health.
AHRQ-funded; HS026395.
Citation: Abreo A, Wu P, Donovan BM .
Infant respiratory syncytial virus bronchiolitis and subsequent risk of pneumonia, otitis media, and antibiotic utilization.
Clin Infect Dis 2020 Jun 24;71(1):211-14. doi: 10.1093/cid/ciz1033..
Keywords: Newborns/Infants, Antibiotics, Medication, Respiratory Conditions, Pneumonia
Kwah JH, Somani SN, Stevens WW
Clinical factors associated with acute exacerbations of chronic rhinosinusitis.
The objective of this retrospective cohort study was to identify clinical factors associated with frequent acute exacerbation of chronic rhinosinusitis (AECRS). Findings showed that patients with frequent episodes of AECRS were characterized by a higher prevalence of asthma, allergic rhinitis, eosinophil count of at least 150 cells per microliter, autoimmune disease, and other allergic and immunologic diseases. These findings identified a high-risk phenotype of patients with chronic rhinosinusitis for preventive interventions to reduce exacerbation frequency.
AHRQ-funded; HS023011.
Citation: Kwah JH, Somani SN, Stevens WW .
Clinical factors associated with acute exacerbations of chronic rhinosinusitis.
J Allergy Clin Immunol 2020 Jun;145(6):1598-605. doi: 10.1016/j.jaci.2020.01.023..
Keywords: Respiratory Conditions, Chronic Conditions
Lacson R, Healey MJ, Cochon LR
Unscheduled radiologic examination orders in the electronic health record: a novel resource for targeting ambulatory diagnostic errors in radiology.
The purpose of this study was to assess the prevalence of unscheduled radiologic examination orders in an electronic health record and to assess the proportion of unscheduled orders that are clinically necessary. Unscheduled radiologic examination orders were retrieved for seven modalities: computed tomography, magnetic resonance imaging, ultrasound, obstetric ultrasound, bone densitometry, mammography, and fluoroscopy. Findings showed that large numbers of radiologic examination orders remain unscheduled in the electronic health record. Identifying and performing clinically necessary unscheduled radiologic examination orders may help reduce diagnostic errors related to diagnosis and treatment delays and enhance patient safety.
AHRQ-funded; HS024722.
Citation: Lacson R, Healey MJ, Cochon LR .
Unscheduled radiologic examination orders in the electronic health record: a novel resource for targeting ambulatory diagnostic errors in radiology.
J Am Coll Radiol 2020 Jun;17(6):765-72. doi: 10.1016/j.jacr.2019.12.021..
Keywords: Electronic Health Records (EHRs), Health Information Technology (HIT), Diagnostic Safety and Quality, Imaging, Patient Safety
Wallace AS, Luther B, Guo JW
Implementing a social determinants screening and referral infrastructure during routine emergency department visits, Utah, 2017-2018.
Emergency departments see a disproportionate share of low-income and uninsured patients. In this study, the investigators developed and evaluated a process for identifying social needs among emergency department patients, for facilitating access to community-based resources, and for integrating clinical and community-based data. They leveraged an academic-community partnership to develop a social needs screening tool and referral process.
AHRQ-funded; HS026505.
Citation: Wallace AS, Luther B, Guo JW .
Implementing a social determinants screening and referral infrastructure during routine emergency department visits, Utah, 2017-2018.
Prev Chronic Dis 2020 Jun 18;17:E45. doi: 10.5888/pcd17.190339..
Keywords: Social Determinants of Health, Emergency Department, Screening, Community-Based Practice, Community Partnerships
Sutherland BL, Pecanac K, Bartels CM
Expect delays: poor connections between rural and urban health systems challenge
Rural Americans with diabetic foot ulcers (DFUs) face a 50% increased risk of major amputation compared to their urban counterparts. In this study, the investigators sought to identify health system barriers contributing to this disparity. The investigators concluded that poor connections across rural and urban healthcare systems were described as the primary health system barrier driving the rural disparity in major amputations.
AHRQ-funded; HS026279.
Citation: Sutherland BL, Pecanac K, Bartels CM .
Expect delays: poor connections between rural and urban health systems challenge
J Foot Ankle Res 2020 Jun 16;13(1):32. doi: 10.1186/s13047-020-00395-y..
Keywords: Rural Health, Health Systems, Disparities, Diabetes, Chronic Conditions, Healthcare Delivery
Gliklich RE, Leavy MB, Cosgrove L
AHRQ Author: Berliner E
Harmonized outcome measures for use in depression patient registries and clinical practice.
This project’s goal was to develop a minimum set of standardized outcome measures relevant to both patients and clinicians that can be collected in depression registries and clinical practice. A multi-stakeholder panel categorized the 27 identified measures using AHRQ's supported Outcome Measures Framework. The panel then identified 10 broadly relevant measures and harmonized definitions for these measures. These harmonized measures represent a minimum set of outcomes that are relevant to clinicians and patients and appropriate for use in depression research and clinical practice.
AHRQ-authored; AHRQ-funded; 290201400004C.
Citation: Gliklich RE, Leavy MB, Cosgrove L .
Harmonized outcome measures for use in depression patient registries and clinical practice.
Ann Intern Med 2020 Jun 16;172(12):803-09. doi: 10.7326/m19-3818..
Keywords: Registries, Depression, Behavioral Health, Outcomes, Patient-Centered Outcomes Research
Stone CA, Stollings JL, Lindsell CJ
Risk-stratified management to remove low-risk penicillin allergy labels in the ICU.
Patients admitted to a medical ICU (MICU) often have chronic illnesses or altered immunity, increasing their need for immediate antibiotic use. In this study, the investigators sought to determine whether MICU patients with low-risk penicillin allergy history could be challenged directly with amoxicillin to have their allergy label safely removed during an acute inpatient stay.
Citation: Stone CA, Stollings JL, Lindsell CJ .
Risk-stratified management to remove low-risk penicillin allergy labels in the ICU.
Am J Respir Crit Care Med 2020 Jun 15;201(12):1572-75. doi: 10.1164/rccm.202001-0089LE..
Keywords: Intensive Care Unit (ICU), Antibiotics, Medication, Medication: Safety, Adverse Drug Events (ADE), Adverse Events, Risk, Diagnostic Safety and Quality
H H, Caton Gilstrap L
AHRQ Author: Tracer H
Screening for cognitive impairment in older adults.
This evidence-based approach paper focuses on putting prevention into action. It discusses screening for cognitive impairment in older adults. It provides case study, case study questions and a discussion.
AHRQ-authored.
Citation: H H, Caton Gilstrap L .
Screening for cognitive impairment in older adults.
Am Fam Physician 2020 Jun 15;101(12):753-54..
Keywords: U.S. Preventive Services Task Force (USPSTF), Dementia, Neurological Disorders, Elderly, Screening, Prevention, Case Study, Evidence-Based Practice, Guidelines
Di Tosto G, McAlearney AS, Fareed N
Metrics for outpatient portal use based on log file analysis: algorithm development.
This study’s goal was to document the functionality of an outpatient portal in the context of outpatient care by mining portal usage data and to provide insights into how patients use this tool. The authors developed a taxonomy of functions and actions and computed analytic metrics, including frequency and comprehensiveness of use. They found that function use was comprehensive at the patient level, while each session was instead limited to the use of one specific function. They hope to promote the replicability of their study at other institutions and to contribute to the establishment of best practices that can facilitate the adoption of behavioral metrics that enable the measurement of patient engagement based on the outpatient portal use.
AHRQ-funded; HS024091; HS024349; HS024379.
Citation: Di Tosto G, McAlearney AS, Fareed N .
Metrics for outpatient portal use based on log file analysis: algorithm development.
J Med Internet Res 2020 Jun 12;22(6):e16849. doi: 10.2196/16849..
Keywords: Electronic Health Records (EHRs), Health Information Technology (HIT), Ambulatory Care and Surgery, Health Services Research (HSR), Research Methodologies
Krist AH, O'Loughlin K, Woolf SH
Enhanced care planning and clinical-community linkages versus usual care to address basic needs of patients with multiple chronic conditions: a clinician-level randomized controlled trial.
This paper describes the beginning of a clinician-level cluster-randomized controlled trial to evaluate how primary care clinicians can participate in community and hospital solutions to connecting patients with needed services and whether doing so is effective in controlling multiple chronic conditions. Electronic health records will be used to identify patients with these conditions, including cardiovascular disease or risks, diabetes, obesity, or depression.
AHRQ-funded; HS026223.
Citation: Krist AH, O'Loughlin K, Woolf SH .
Enhanced care planning and clinical-community linkages versus usual care to address basic needs of patients with multiple chronic conditions: a clinician-level randomized controlled trial.
Trials 2020 Jun 11;21(1):517. doi: 10.1186/s13063-020-04463-3..
Keywords: Chronic Conditions, Primary Care, Health Promotion, Access to Care
Simione M, Sharifi M, Gerber MW
Family-centeredness of childhood obesity interventions: psychometrics & outcomes of the family-centered care assessment tool.
The purpose of this study was to evaluate the psychometric properties of a modified version of the Family Centered-Care Assessment (mFCCA) tool and to assess the family-centeredness of two clinical-community childhood obesity interventions. Using the mFCCA which demonstrated good psychometric properties for the assessment of family-centered care among parents of children with obesity, the investigators found that individualized health coaching is a family-centered approach to pediatric weight management.
AHRQ-funded; HS024332; HS022986.
Citation: Simione M, Sharifi M, Gerber MW .
Family-centeredness of childhood obesity interventions: psychometrics & outcomes of the family-centered care assessment tool.
Health Qual Life Outcomes 2020 Jun 11;18(1):179. doi: 10.1186/s12955-020-01431-y..
Keywords: Children/Adolescents, Obesity: Weight Management, Obesity, Patient-Centered Healthcare, Family Health and History
Fritz SA, Shapiro DJ, Hersh AL
National trends in incidence of purulent skin and soft tissue infections in patients presenting to ambulatory and emergency department settings, 2000-2015.
This study looked at national trends in the incidence of outpatient visits for skin infections from 2000-2015, which peaked in 2010-2013, followed by a plateau in 2014 and 2015. Cephalexin was the most frequently prescribed antibiotic at the beginning of the study, with trimethoprim-sulfamethoxazole then becoming the most frequently prescribed by the end of the study period.
AHRQ-funded; HS021736; HS024269.
Citation: Fritz SA, Shapiro DJ, Hersh AL .
National trends in incidence of purulent skin and soft tissue infections in patients presenting to ambulatory and emergency department settings, 2000-2015.
Clin Infect Dis 2020 Jun 10;70(12):2715-18. doi: 10.1093/cid/ciz977..
Keywords: Skin Conditions, Ambulatory Care and Surgery, Emergency Department, Antibiotics, Medication